Phenotype measure:   Naggert1   BMC_fat8

ID, description, units MPD:14314   BMC_fat8   bone mineral content (BMC)   [g]
high-fat diet study
Data set, strains Naggert1   inbred w/CC7   39 strains     sex: both     age: 15-17wks
Procedure DXA
Ontology mappings

  STRAIN COMPARISON PLOT
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Naggert1 - bone mineral content (BMC)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested39 strains38 strains
Mean of the strain means0.444   g 0.470   g
Median of the strain means0.437   g 0.483   g
SD of the strain means± 0.0939 ± 0.102
Coefficient of variation (CV)0.212 0.217
Min–max range of strain means0.264   –   0.613   g 0.226   –   0.650   g
Mean sample size per strain9.8   mice 9.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0446 0.0446 33.9248 < 0.0001
strain 35 6.5147 0.1861 141.4389 < 0.0001
sex:strain 35 0.3883 0.0111 8.4294 < 0.0001
Residuals 639 0.8409 0.0013


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.495 0.0423   8 0.0149 0.0855 0.447, 0.552 0.54
129S1/SvImJ m 0.494 0.0354   10 0.0112 0.0716 0.435, 0.55 0.23
A/J f 0.404 0.0221   10 0.00699 0.0547 0.368, 0.44 -0.43
A/J m 0.388 0.0329   10 0.0104 0.0847 0.356, 0.454 -0.81
AKR/J f 0.612 0.0425   18 0.01 0.0695 0.543, 0.704 1.79
AKR/J m 0.65 0.0574   17 0.0139 0.0883 0.549, 0.744 1.76
BALB/cByJ m 0.485 0.0538   9 0.0179 0.111 0.369, 0.536 0.14
BALB/cJ f 0.507 0.0368   9 0.0123 0.0726 0.455, 0.564 0.67
BALB/cJ m 0.533 0.0425   10 0.0134 0.0798 0.47, 0.602 0.61
BTBR T+ Itpr3tf/J f 0.606 0.0368   10 0.0116 0.0606 0.554, 0.665 1.72
BTBR T+ Itpr3tf/J m 0.592 0.0345   10 0.0109 0.0584 0.517, 0.632 1.19
BUB/BnJ f 0.539 0.0502   12 0.0145 0.093 0.466, 0.637 1.01
BUB/BnJ m 0.533 0.0302   8 0.0107 0.0568 0.494, 0.565 0.61
C3H/HeJ f 0.534 0.0271   10 0.00858 0.0508 0.492, 0.564 0.96
C3H/HeJ m 0.608 0.035   10 0.0111 0.0575 0.556, 0.666 1.35
C57BL/10J f 0.428 0.0289   9 0.00963 0.0675 0.388, 0.467 -0.17
C57BL/10J m 0.461 0.0301   12 0.00869 0.0653 0.403, 0.5 -0.09
C57BL/6J f 0.407 0.0204   10 0.00644 0.05 0.368, 0.433 -0.39
C57BL/6J m 0.463 0.0253   10 0.008 0.0546 0.431, 0.509 -0.07
C57BLKS/J f 0.374 0.0277   12 0.00799 0.0739 0.316, 0.421 -0.75
C57BLKS/J m 0.39 0.0165   10 0.00523 0.0424 0.367, 0.418 -0.79
C57BR/cdJ f 0.571 0.0509   12 0.0147 0.0892 0.5, 0.676 1.35
C57BR/cdJ m 0.522 0.034   10 0.0108 0.0651 0.47, 0.565 0.51
C57L/J f 0.516 0.0468   10 0.0148 0.0908 0.441, 0.571 0.77
C57L/J m 0.512 0.039   10 0.0123 0.0761 0.456, 0.578 0.41
C58/J f 0.425 0.0328   11 0.00989 0.0771 0.353, 0.448 -0.2
C58/J m 0.413 0.0326   9 0.0109 0.0789 0.383, 0.487 -0.56
CAST/EiJ f 0.323 0.0275   9 0.00918 0.0853 0.27, 0.362 -1.29
CAST/EiJ m 0.326 0.0292   8 0.0103 0.0898 0.288, 0.364 -1.41
CBA/J f 0.499 0.0332   10 0.0105 0.0665 0.446, 0.546 0.59
CBA/J m 0.564 0.0458   8 0.0162 0.0811 0.484, 0.632 0.92
CZECHII/EiJ f 0.338 0.0484   16 0.0121 0.143 0.279, 0.476 -1.13
CZECHII/EiJ m 0.292 0.0281   11 0.00846 0.0962 0.242, 0.328 -1.75
DBA/1J f 0.426 0.0302   12 0.00871 0.0708 0.38, 0.46 -0.19
DBA/1J m 0.414 0.0243   8 0.00858 0.0587 0.374, 0.441 -0.55
DBA/2J f 0.437 0.0186   9 0.00621 0.0427 0.416, 0.478 -0.07
DBA/2J m 0.408 0.0244   9 0.00814 0.0598 0.374, 0.442 -0.61
FVB/NJ f 0.495 0.0306   9 0.0102 0.0618 0.439, 0.54 0.54
FVB/NJ m 0.56 0.0363   10 0.0115 0.0649 0.477, 0.596 0.88
I/LnJ f 0.422 0.0287   9 0.00956 0.0679 0.351, 0.449 -0.23
I/LnJ m 0.422 0.0295   12 0.00851 0.0699 0.37, 0.466 -0.47
JF1/MsJ f 0.356 0.028   10 0.00886 0.0787 0.312, 0.4 -0.94
JF1/MsJ m 0.318 0.0869   7 0.0328 0.273 0.271, 0.514 -1.49
KK/HlJ f 0.539 0.0704   8 0.0249 0.131 0.452, 0.67 1.01
KK/HlJ m 0.606 0.05   9 0.0167 0.0825 0.545, 0.7 1.33
LP/J f 0.514 0.0474   9 0.0158 0.0922 0.46, 0.586 0.75
LP/J m 0.54 0.039   9 0.013 0.0722 0.459, 0.586 0.68
MA/MyJ f 0.447 0.0205   9 0.00682 0.0458 0.423, 0.472 0.03
MA/MyJ m 0.449 0.033   10 0.0104 0.0736 0.412, 0.522 -0.21
MOLF/EiJ f 0.295 0.0345   7 0.013 0.117 0.252, 0.353 -1.59
MOLF/EiJ m 0.316 0.0229   7 0.00864 0.0724 0.286, 0.351 -1.51
MSM/MsJ f 0.264 0.0181   8 0.00639 0.0683 0.242, 0.297 -1.92
MSM/MsJ m 0.226 0.0147   12 0.00424 0.0648 0.206, 0.25 -2.39
NOD/ShiLtJ f 0.476 0.0464   15 0.012 0.0975 0.408, 0.569 0.34
NOD/ShiLtJ m 0.482 0.0196   8 0.00694 0.0407 0.462, 0.523 0.12
NON/ShiLtJ f 0.613 0.021   10 0.00663 0.0342 0.58, 0.641 1.8
NON/ShiLtJ m 0.518 0.0253   10 0.00801 0.0489 0.481, 0.558 0.47
NZB/BlNJ m 0.636 0.0286   10 0.00904 0.045 0.605, 0.684 1.62
NZW/LacJ f 0.543 0.035   10 0.0111 0.0645 0.482, 0.586 1.05
NZW/LacJ m 0.603 0.023   10 0.00727 0.0381 0.578, 0.643 1.3
PERA/EiJ f 0.389 0.0322   9 0.0107 0.0828 0.319, 0.422 -0.59
PERA/EiJ m 0.508 0.0236   9 0.00785 0.0464 0.478, 0.543 0.37
PL/J f 0.37 0.0211   10 0.00668 0.057 0.318, 0.39 -0.79
PWK/PhJ f 0.338 0.03   7 0.0113 0.0889 0.297, 0.375 -1.13
RIIIS/J f 0.442 0.0221   9 0.00737 0.05 0.401, 0.48 -0.02
SEA/GnJ f 0.524 0.0355   9 0.0118 0.0677 0.474, 0.572 0.85
SEA/GnJ m 0.511 0.0279   10 0.00882 0.0546 0.476, 0.56 0.4
SJL/J f 0.46 0.0252   9 0.00838 0.0547 0.418, 0.499 0.17
SJL/J m 0.523 0.0273   15 0.00704 0.0522 0.478, 0.569 0.52
SM/J f 0.272 0.0367   9 0.0122 0.135 0.22, 0.343 -1.83
SM/J m 0.407 0.046   9 0.0153 0.113 0.369, 0.522 -0.62
SPRET/EiJ f 0.412 0.0407   4 0.0204 0.0989 0.356, 0.443 -0.34
SPRET/EiJ m 0.392 0.0235   6 0.00961 0.0601 0.365, 0.434 -0.77
SWR/J f 0.404 0.0379   10 0.012 0.0938 0.316, 0.443 -0.43
SWR/J m 0.464 0.0485   10 0.0153 0.105 0.364, 0.537 -0.06
WSB/EiJ f 0.3 0.027   8 0.00954 0.0898 0.261, 0.336 -1.53
WSB/EiJ m 0.341 0.0337   9 0.0112 0.0989 0.297, 0.386 -1.27


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.4948 0.0128 0.5199 0.4696
129S1/SvImJ m 0.4942 0.0115 0.5167 0.4717
A/J f 0.4043 0.0115 0.4268 0.3818
A/J m 0.3883 0.0115 0.4108 0.3658
AKR/J f 0.6122 0.0086 0.629 0.5954
AKR/J m 0.6502 0.0088 0.6675 0.6329
BALB/cJ f 0.5066 0.0121 0.5303 0.4828
BALB/cJ m 0.5328 0.0115 0.5553 0.5103
BTBR T+ Itpr3tf/J f 0.6061 0.0115 0.6286 0.5836
BTBR T+ Itpr3tf/J m 0.5915 0.0115 0.614 0.569
BUB/BnJ f 0.5392 0.0105 0.5597 0.5186
BUB/BnJ m 0.5326 0.0128 0.5578 0.5074
C3H/HeJ f 0.5341 0.0115 0.5566 0.5116
C3H/HeJ m 0.6078 0.0115 0.6303 0.5853
C57BL/10J f 0.4279 0.0121 0.4516 0.4041
C57BL/10J m 0.4612 0.0105 0.4817 0.4406
C57BL/6J f 0.4073 0.0115 0.4298 0.3848
C57BL/6J m 0.463 0.0115 0.4855 0.4405
C57BLKS/J f 0.3744 0.0105 0.395 0.3539
C57BLKS/J m 0.3903 0.0115 0.4128 0.3678
C57BR/cdJ f 0.5713 0.0105 0.5918 0.5507
C57BR/cdJ m 0.5225 0.0115 0.545 0.5
C57L/J f 0.5159 0.0115 0.5384 0.4934
C57L/J m 0.5117 0.0115 0.5342 0.4892
C58/J f 0.4255 0.0109 0.4469 0.404
C58/J m 0.4129 0.0121 0.4366 0.3891
CAST/EiJ f 0.323 0.0121 0.3467 0.2993
CAST/EiJ m 0.3257 0.0128 0.3509 0.3006
CBA/J f 0.4986 0.0115 0.5211 0.4761
CBA/J m 0.5643 0.0128 0.5894 0.5391
CZECHII/EiJ f 0.3384 0.0091 0.3562 0.3206
CZECHII/EiJ m 0.2918 0.0109 0.3133 0.2703
DBA/1J f 0.4262 0.0105 0.4467 0.4056
DBA/1J m 0.4136 0.0128 0.4388 0.3884
DBA/2J f 0.4367 0.0121 0.4604 0.4129
DBA/2J m 0.4084 0.0121 0.4322 0.3847
FVB/NJ f 0.4946 0.0121 0.5183 0.4708
FVB/NJ m 0.5598 0.0115 0.5823 0.5373
I/LnJ f 0.4224 0.0121 0.4462 0.3987
I/LnJ m 0.4217 0.0105 0.4422 0.4011
JF1/MsJ f 0.3559 0.0115 0.3784 0.3334
JF1/MsJ m 0.3183 0.0137 0.3452 0.2914
KK/HlJ f 0.5388 0.0128 0.5639 0.5136
KK/HlJ m 0.6057 0.0121 0.6294 0.5819
LP/J f 0.5137 0.0121 0.5374 0.4899
LP/J m 0.5402 0.0121 0.564 0.5165
MA/MyJ f 0.4472 0.0121 0.471 0.4235
MA/MyJ m 0.4492 0.0115 0.4717 0.4267
MOLF/EiJ f 0.2953 0.0137 0.3222 0.2684
MOLF/EiJ m 0.3157 0.0137 0.3426 0.2888
MSM/MsJ f 0.2643 0.0128 0.2894 0.2391
MSM/MsJ m 0.2264 0.0105 0.247 0.2059
NOD/ShiLtJ f 0.4757 0.0094 0.4941 0.4573
NOD/ShiLtJ m 0.4823 0.0128 0.5074 0.4571
NON/ShiLtJ f 0.6129 0.0115 0.6354 0.5904
NON/ShiLtJ m 0.5185 0.0115 0.541 0.496
NZW/LacJ f 0.5431 0.0115 0.5656 0.5206
NZW/LacJ m 0.6029 0.0115 0.6254 0.5804
PERA/EiJ f 0.3886 0.0121 0.4123 0.3648
PERA/EiJ m 0.5078 0.0121 0.5315 0.484
SEA/GnJ f 0.5236 0.0121 0.5473 0.4998
SEA/GnJ m 0.5111 0.0115 0.5336 0.4886
SJL/J f 0.4597 0.0121 0.4834 0.4359
SJL/J m 0.5231 0.0094 0.5415 0.5047
SM/J f 0.2721 0.0121 0.2959 0.2484
SM/J m 0.4067 0.0121 0.4304 0.3829
SPRET/EiJ f 0.4115 0.0181 0.4471 0.3759
SPRET/EiJ m 0.3917 0.0148 0.4207 0.3626
SWR/J f 0.4038 0.0115 0.4263 0.3813
SWR/J m 0.4637 0.0115 0.4862 0.4412
WSB/EiJ f 0.3004 0.0128 0.3256 0.2752
WSB/EiJ m 0.3411 0.0121 0.3649 0.3174


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.4945 0.0086 0.5114 0.4776
A/J both 0.3963 0.0081 0.4122 0.3804
AKR/J both 0.6312 0.0061 0.6432 0.6191
BALB/cJ both 0.5197 0.0083 0.536 0.5033
BTBR T+ Itpr3tf/J both 0.5988 0.0081 0.6147 0.5829
BUB/BnJ both 0.5359 0.0083 0.5522 0.5196
C3H/HeJ both 0.571 0.0081 0.5869 0.555
C57BL/10J both 0.4445 0.008 0.4602 0.4288
C57BL/6J both 0.4352 0.0081 0.4511 0.4192
C57BLKS/J both 0.3824 0.0078 0.3976 0.3671
C57BR/cdJ both 0.5469 0.0078 0.5621 0.5316
C57L/J both 0.5138 0.0081 0.5297 0.4979
C58/J both 0.4192 0.0082 0.4352 0.4032
CAST/EiJ both 0.3244 0.0088 0.3417 0.3071
CBA/J both 0.5314 0.0086 0.5483 0.5145
CZECHII/EiJ both 0.3151 0.0071 0.329 0.3011
DBA/1J both 0.4199 0.0083 0.4362 0.4036
DBA/2J both 0.4226 0.0086 0.4393 0.4058
FVB/NJ both 0.5272 0.0083 0.5435 0.5108
I/LnJ both 0.4221 0.008 0.4378 0.4063
JF1/MsJ both 0.3371 0.0089 0.3546 0.3195
KK/HlJ both 0.5722 0.0088 0.5895 0.5549
LP/J both 0.5269 0.0086 0.5437 0.5102
MA/MyJ both 0.4482 0.0083 0.4646 0.4318
MOLF/EiJ both 0.3055 0.0097 0.3245 0.2865
MSM/MsJ both 0.2453 0.0083 0.2616 0.2291
NOD/ShiLtJ both 0.479 0.0079 0.4946 0.4634
NON/ShiLtJ both 0.5657 0.0081 0.5816 0.5498
NZW/LacJ both 0.573 0.0081 0.5889 0.5571
PERA/EiJ both 0.4482 0.0086 0.465 0.4314
SEA/GnJ both 0.5173 0.0083 0.5337 0.501
SJL/J both 0.4914 0.0076 0.5064 0.4763
SM/J both 0.3394 0.0086 0.3562 0.3226
SPRET/EiJ both 0.4016 0.0117 0.4246 0.3786
SWR/J both 0.4338 0.0081 0.4497 0.4178
WSB/EiJ both 0.3207 0.0088 0.3381 0.3034




  GWAS USING LINEAR MIXED MODELS