Project measure / variable:   Naggert1   bw_fat8

ID, description, units MPD:14308   bw_fat8   body weight   [g]  
high-fat diet study
Data set, strains Naggert1   inbred w/CC7   41 strains     sex: both     age: 15-17wks
Procedure body weight
Ontology mappings

  STRAIN COMPARISON PLOT
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Naggert1 - body weight



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested39 strains38 strains
Mean of the strain means22.4   g 27.9   g
Median of the strain means22.3   g 28.6   g
SD of the strain means± 5.59 ± 6.88
Coefficient of variation (CV)0.249 0.246
Min–max range of strain means12.0   –   35.4   g 15.0   –   41.6   g
Mean sample size per strain9.8   mice 9.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 4086.7902 4086.7902 702.6778 < 0.0001
strain 35 27103.0632 774.3732 133.1448 < 0.0001
sex:strain 35 1389.4988 39.7 6.826 < 0.0001
Residuals 639 3716.4388 5.816


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 22.3 0.645   8 0.228 0.0289 21.3, 23.2 -0.02
129S1/SvImJ m 30.5 3.18   10 1.01 0.104 26.3, 35.4 0.37
A/J f 21.2 0.859   10 0.272 0.0405 19.6, 22.2 -0.22
A/J m 24.0 2.1   10 0.663 0.0875 20.4, 27.4 -0.57
AKR/J f 35.4 4.18   18 0.986 0.118 23.6, 38.9 2.32
AKR/J m 41.6 5.48   17 1.33 0.132 30.0, 50.5 1.98
BALB/cByJ m 28.3 4.11   9 1.37 0.145 18.8, 31.3 0.05
BALB/cJ f 24.7 1.73   9 0.576 0.0699 22.0, 27.9 0.41
BALB/cJ m 29.2 0.985   10 0.311 0.0338 28.1, 31.3 0.18
BTBR T+ Itpr3tf/J f 32.4 1.91   10 0.606 0.059 29.8, 35.3 1.79
BTBR T+ Itpr3tf/J m 41.2 2.32   10 0.733 0.0562 38.4, 45.0 1.93
BUB/BnJ f 27.4 2.18   12 0.629 0.0794 24.7, 32.4 0.89
BUB/BnJ m 31.6 0.69   8 0.244 0.0218 30.2, 32.2 0.53
C3H/HeJ f 23.0 2.99   10 0.947 0.13 19.1, 27.2 0.1
C3H/HeJ m 31.9 3.02   10 0.956 0.0949 27.3, 37.7 0.58
C57BL/10J f 21.8 1.66   9 0.552 0.0761 20.5, 25.6 -0.11
C57BL/10J m 29.4 1.41   12 0.408 0.0481 27.1, 31.0 0.21
C57BL/6J f 20.7 1.14   10 0.361 0.055 18.9, 22.8 -0.31
C57BL/6J m 25.0 1.32   10 0.416 0.0527 23.1, 26.7 -0.43
C57BLKS/J f 22.1 1.18   12 0.341 0.0535 20.2, 23.4 -0.06
C57BLKS/J m 25.8 1.85   10 0.585 0.0717 23.8, 29.3 -0.31
C57BR/cdJ f 23.1 1.98   12 0.571 0.0858 19.2, 25.8 0.12
C57BR/cdJ m 32.2 3.72   10 1.18 0.115 25.7, 36.3 0.62
C57L/J f 20.5 1.04   10 0.329 0.0509 18.9, 22.1 -0.34
C57L/J m 28.8 1.92   10 0.608 0.0668 25.8, 31.1 0.12
C58/J f 23.1 2.31   11 0.696 0.1 19.0, 26.7 0.12
C58/J m 25.4 1.49   9 0.497 0.0587 23.5, 28.1 -0.37
CAST/EiJ f 14.9 0.682   9 0.227 0.0457 13.6, 15.9 -1.35
CAST/EiJ m 17.5 0.756   8 0.267 0.0432 16.3, 18.6 -1.52
CBA/J f 28.0 1.77   10 0.561 0.0632 25.9, 31.1 1.0
CBA/J m 37.3 2.79   8 0.987 0.0749 32.9, 40.3 1.36
CZECHII/EiJ f 13.1 1.22   16 0.304 0.0926 11.1, 15.8 -1.67
CZECHII/EiJ m 15.0 1.22   11 0.368 0.0815 12.6, 16.8 -1.88
DBA/1J f 22.7 1.84   12 0.53 0.0809 19.5, 25.5 0.05
DBA/1J m 27.2 4.24   8 1.5 0.156 21.4, 34.5 -0.11
DBA/2J f 26.4 1.87   9 0.622 0.0708 23.0, 28.5 0.71
DBA/2J m 32.9 3.01   9 1.0 0.0914 26.9, 38.1 0.72
FVB/NJ f 23.3 2.57   9 0.857 0.11 19.9, 26.7 0.16
FVB/NJ m 30.7 1.64   10 0.518 0.0534 27.6, 32.9 0.4
I/LnJ f 21.4 1.54   9 0.515 0.0721 19.3, 23.3 -0.18
I/LnJ m 25.8 2.23   12 0.645 0.0865 22.7, 29.6 -0.31
JF1/MsJ f 20.2 1.92   10 0.606 0.0948 16.7, 22.7 -0.4
JF1/MsJ m 25.4 3.36   7 1.27 0.133 20.5, 30.8 -0.37
KK/HlJ f 28.4 5.24   8 1.85 0.185 23.6, 40.0 1.07
KK/HlJ m 38.9 1.35   9 0.452 0.0349 36.2, 40.9 1.59
LP/J f 25.0 4.46   9 1.49 0.179 19.5, 34.5 0.46
LP/J m 31.9 3.68   9 1.23 0.116 25.8, 37.9 0.58
MA/MyJ f 22.5 1.22   9 0.405 0.0539 20.9, 24.6 0.01
MA/MyJ m 26.8 3.04   10 0.963 0.114 23.4, 33.0 -0.17
MOLF/EiJ f 13.6 1.26   7 0.477 0.093 11.8, 14.8 -1.58
MOLF/EiJ m 16.1 1.06   7 0.4 0.0659 14.8, 17.8 -1.72
MSM/MsJ f 12.5 1.01   8 0.356 0.0807 10.8, 13.6 -1.78
MSM/MsJ m 15.6 1.68   12 0.484 0.107 12.3, 17.7 -1.79
NOD/ShiLtJ f 26.1 2.69   15 0.695 0.103 20.4, 31.8 0.66
NOD/ShiLtJ m 29.0 2.47   8 0.874 0.0852 25.1, 32.4 0.15
NON/ShiLtJ f 32.8 1.97   10 0.622 0.0599 30.4, 35.2 1.86
NON/ShiLtJ m 30.8 1.37   10 0.434 0.0445 29.1, 33.6 0.42
NZB/BlNJ m 34.8 3.89   10 1.23 0.112 29.9, 42.2 1.0
NZW/LacJ f 30.8 1.67   10 0.529 0.0544 28.0, 32.9 1.5
NZW/LacJ m 37.3 3.76   10 1.19 0.101 29.6, 42.8 1.36
PERA/EiJ f 24.1 1.21   9 0.405 0.0503 21.8, 25.5 0.3
PERA/EiJ m 26.9 0.8   9 0.267 0.0297 25.8, 28.2 -0.15
PL/J f 12.0 3.08   10 0.973 0.256 8.89, 17.8 -1.86
PWK/PhJ f 18.7 1.93   7 0.728 0.103 14.6, 20.1 -0.67
RIIIS/J f 19.3 0.98   9 0.327 0.0509 18.0, 20.7 -0.56
SEA/GnJ f 26.9 1.75   9 0.582 0.0649 25.2, 31.1 0.8
SEA/GnJ m 29.2 2.0   10 0.633 0.0685 25.3, 33.0 0.18
SJL/J f 21.7 1.44   9 0.48 0.0663 19.2, 24.6 -0.13
SJL/J m 26.6 1.74   15 0.45 0.0655 23.8, 30.6 -0.2
SM/J f 17.7 2.33   9 0.775 0.131 12.8, 20.4 -0.84
SM/J m 23.7 2.18   9 0.727 0.0919 21.0, 27.6 -0.62
SPRET/EiJ f 19.4 4.54   4 2.27 0.234 15.1, 25.8 -0.54
SPRET/EiJ m 16.7 3.21   6 1.31 0.193 14.4, 23.0 -1.63
SWR/J f 21.8 1.69   10 0.534 0.0774 18.2, 24.0 -0.11
SWR/J m 25.5 2.92   10 0.925 0.115 18.7, 28.5 -0.35
WSB/EiJ f 13.3 0.887   8 0.314 0.0668 12.4, 14.5 -1.63
WSB/EiJ m 15.3 1.22   9 0.405 0.0793 13.7, 17.6 -1.84


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 22.325 0.8526 23.9993 20.6507
129S1/SvImJ m 30.53 0.7626 32.0276 29.0324
A/J f 21.2 0.7626 22.6976 19.7024
A/J m 23.98 0.7626 25.4776 22.4824
AKR/J f 35.3944 0.5684 36.5107 34.2782
AKR/J m 41.5588 0.5849 42.7074 40.4102
BALB/cJ f 24.7444 0.8039 26.323 23.1659
BALB/cJ m 29.16 0.7626 30.6576 27.6624
BTBR T+ Itpr3tf/J f 32.43 0.7626 33.9276 30.9324
BTBR T+ Itpr3tf/J m 41.21 0.7626 42.7076 39.7124
BUB/BnJ f 27.4417 0.6962 28.8087 26.0746
BUB/BnJ m 31.5875 0.8526 33.2618 29.9132
C3H/HeJ f 23.04 0.7626 24.5376 21.5424
C3H/HeJ m 31.87 0.7626 33.3676 30.3724
C57BL/10J f 21.7889 0.8039 23.3675 20.2103
C57BL/10J m 29.3667 0.6962 30.7337 27.9996
C57BL/6J f 20.73 0.7626 22.2276 19.2324
C57BL/6J m 24.97 0.7626 26.4676 23.4724
C57BLKS/J f 22.1083 0.6962 23.4754 20.7413
C57BLKS/J m 25.81 0.7626 27.3076 24.3124
C57BR/cdJ f 23.0583 0.6962 24.4254 21.6913
C57BR/cdJ m 32.25 0.7626 33.7476 30.7524
C57L/J f 20.46 0.7626 21.9576 18.9624
C57L/J m 28.79 0.7626 30.2876 27.2924
C58/J f 23.0909 0.7271 24.5188 21.663
C58/J m 25.4222 0.8039 27.0008 23.8437
CAST/EiJ f 14.9333 0.8039 16.5119 13.3548
CAST/EiJ m 17.5 0.8526 19.1743 15.8257
CBA/J f 28.04 0.7626 29.5376 26.5424
CBA/J m 37.275 0.8526 38.9493 35.6007
CZECHII/EiJ f 13.1312 0.6029 14.3152 11.9473
CZECHII/EiJ m 14.9909 0.7271 16.4188 13.563
DBA/1J f 22.6917 0.6962 24.0587 21.3246
DBA/1J m 27.225 0.8526 28.8993 25.5507
DBA/2J f 26.3556 0.8039 27.9341 24.777
DBA/2J m 32.9 0.8039 34.4786 31.3214
FVB/NJ f 23.3 0.8039 24.8786 21.7214
FVB/NJ m 30.69 0.7626 32.1876 29.1924
I/LnJ f 21.4111 0.8039 22.9897 19.8325
I/LnJ m 25.825 0.6962 27.1921 24.4579
JF1/MsJ f 20.22 0.7626 21.7176 18.7224
JF1/MsJ m 25.3571 0.9115 27.1471 23.5672
KK/HlJ f 28.4125 0.8526 30.0868 26.7382
KK/HlJ m 38.8667 0.8039 40.4452 37.2881
LP/J f 24.9556 0.8039 26.5341 23.377
LP/J m 31.8778 0.8039 33.4563 30.2992
MA/MyJ f 22.5444 0.8039 24.123 20.9659
MA/MyJ m 26.79 0.7626 28.2876 25.2924
MOLF/EiJ f 13.5571 0.9115 15.3471 11.7672
MOLF/EiJ m 16.0714 0.9115 17.8614 14.2815
MSM/MsJ f 12.475 0.8526 14.1493 10.8007
MSM/MsJ m 15.6 0.6962 16.9671 14.2329
NOD/ShiLtJ f 26.1067 0.6227 27.3294 24.8839
NOD/ShiLtJ m 29.0 0.8526 30.6743 27.3257
NON/ShiLtJ f 32.83 0.7626 34.3276 31.3324
NON/ShiLtJ m 30.8 0.7626 32.2976 29.3024
NZW/LacJ f 30.76 0.7626 32.2576 29.2624
NZW/LacJ m 37.33 0.7626 38.8276 35.8324
PERA/EiJ f 24.1222 0.8039 25.7008 22.5437
PERA/EiJ m 26.9444 0.8039 28.523 25.3659
SEA/GnJ f 26.9 0.8039 28.4786 25.3214
SEA/GnJ m 29.23 0.7626 30.7276 27.7324
SJL/J f 21.7111 0.8039 23.2897 20.1325
SJL/J m 26.58 0.6227 27.8028 25.3572
SM/J f 17.7111 0.8039 19.2897 16.1325
SM/J m 23.7333 0.8039 25.3119 22.1548
SPRET/EiJ f 19.4 1.2058 21.7679 17.0321
SPRET/EiJ m 16.6667 0.9845 18.6 14.7333
SWR/J f 21.82 0.7626 23.3176 20.3224
SWR/J m 25.51 0.7626 27.0076 24.0124
WSB/EiJ f 13.2875 0.8526 14.9618 11.6132
WSB/EiJ m 15.3333 0.8039 16.9119 13.7548


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 26.4275 0.572 27.5507 25.3043
A/J both 22.59 0.5393 23.6489 21.5311
AKR/J both 38.4766 0.4078 39.2774 37.6758
BALB/cJ both 26.9522 0.554 28.0402 25.8643
BTBR T+ Itpr3tf/J both 36.82 0.5393 37.8789 35.7611
BUB/BnJ both 29.5146 0.5504 30.5954 28.4338
C3H/HeJ both 27.455 0.5393 28.5139 26.3961
C57BL/10J both 25.5778 0.5317 26.6219 24.5337
C57BL/6J both 22.85 0.5393 23.9089 21.7911
C57BLKS/J both 23.9592 0.5163 24.973 22.9453
C57BR/cdJ both 27.6542 0.5163 28.668 26.6403
C57L/J both 24.625 0.5393 25.6839 23.5661
C58/J both 24.2566 0.542 25.3208 23.1923
CAST/EiJ both 16.2167 0.5859 17.3672 15.0661
CBA/J both 32.6575 0.572 33.7807 31.5343
CZECHII/EiJ both 14.0611 0.4723 14.9885 13.1337
DBA/1J both 24.9583 0.5504 26.0391 23.8776
DBA/2J both 29.6278 0.5684 30.744 28.5116
FVB/NJ both 26.995 0.554 28.083 25.907
I/LnJ both 23.6181 0.5317 24.6622 22.5739
JF1/MsJ both 22.7886 0.5942 23.9555 21.6217
KK/HlJ both 33.6396 0.5859 34.7902 32.489
LP/J both 28.4167 0.5684 29.5329 27.3005
MA/MyJ both 24.6672 0.554 25.7552 23.5793
MOLF/EiJ both 14.8143 0.6445 16.08 13.5486
MSM/MsJ both 14.0375 0.5504 15.1183 12.9567
NOD/ShiLtJ both 27.5533 0.5279 28.59 26.5167
NON/ShiLtJ both 31.815 0.5393 32.8739 30.7561
NZW/LacJ both 34.045 0.5393 35.1039 32.9861
PERA/EiJ both 25.5333 0.5684 26.6495 24.4171
SEA/GnJ both 28.065 0.554 29.153 26.977
SJL/J both 24.1456 0.5084 25.1439 23.1472
SM/J both 20.7222 0.5684 21.8384 19.606
SPRET/EiJ both 18.0333 0.7784 19.5618 16.5049
SWR/J both 23.665 0.5393 24.7239 22.6061
WSB/EiJ both 14.3104 0.5859 15.461 13.1598




  GWAS USING LINEAR MIXED MODELS