Project measure / variable:   Johnson1   pip32kHz_old

ID, description, units MPD:1410   pip32kHz_old   auditory brainstem response (ABR) threshold, 15-72 wk old group, sound pressure level   [dB]  32kHz pip stimulus  
Data set, strains Johnson1   inbred   27 strains     sex: both     age: 15-72wks
Procedure ABR test
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  STRAIN COMPARISON PLOT
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Johnson1 - auditory brainstem response (ABR) threshold, 15-72 wk old group, sound pressure level 32kHz pip stimulus



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested21 strains19 strains
Mean of the strain means69.5   dB 72.5   dB
Median of the strain means65.0   dB 71.6   dB
SD of the strain means± 23.9 ± 25.4
Coefficient of variation (CV)0.344 0.351
Min–max range of strain means40.6   –   117   dB 37.0   –   112   dB
Mean sample size per strain11.4   mice 10.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 208.7945 208.7945 0.7692 0.3811
strain 12 149023.4866 12418.6239 45.7483 < 0.0001
sex:strain 12 6447.727 537.3106 1.9794 0.0253
Residuals 340 92294.8361 271.4554


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129P3/J f 84.9 19.3   9 6.43 0.227 60.0, 119.0 0.64
129P3/J m 84.4 9.17   9 3.06 0.109 70.0, 100.0 0.47
129T2/SvEmsJ m 63.3 6.06   6 2.47 0.0956 55.0, 70.0 -0.36
129X1/SvJ m 69.4 20.3   8 7.16 0.292 50.0, 95.0 -0.12
A/HeJ f 61.0 6.69   43 1.02 0.11 45.0, 75.0 -0.36
A/HeJ m 59.2 11.5   13 3.19 0.194 40.0, 80.0 -0.52
A/J f 94.8 28.3   18 6.66 0.298 50.0, 119.0 1.06
A/J m 112.0 11.5   19 2.63 0.102 75.0, 119.0 1.55
A/WySnJ f 72.4 14.5   42 2.23 0.2 40.0, 110.0 0.12
A/WySnJ m 74.0 16.0   24 3.27 0.217 45.0, 105.0 0.06
BUB/BnJ m 107.0 11.0   7 4.15 0.102 95.0, 119.0 1.36
C3H/HeJ f 42.5 8.22   6 3.35 0.193 30.0, 50.0 -1.13
C57BL/6J f 74.2 30.4   17 7.38 0.41 35.0, 119.0 0.2
C57BL/6J m 86.4 30.3   23 6.32 0.351 35.0, 119.0 0.55
C57BLKS/J f 65.0 15.5   7 5.88 0.239 50.0, 95.0 -0.19
C57BR/cdJ f 95.1 16.4   16 4.1 0.172 55.0, 119.0 1.07
C57BR/cdJ m 83.2 12.9   11 3.89 0.155 50.0, 100.0 0.42
C57L/J f 99.4 12.7   22 2.7 0.128 75.0, 119.0 1.25
C57L/J m 88.9 7.41   9 2.47 0.0833 80.0, 100.0 0.65
CAST/EiJ f 45.0 8.94   6 3.65 0.199 35.0, 60.0 -1.03
CAST/EiJ m 43.3 19.7   9 6.56 0.454 30.0, 90.0 -1.15
CBA/CaJ f 40.6 6.59   17 1.6 0.162 30.0, 60.0 -1.21
CBA/CaJ m 37.0 5.87   10 1.86 0.159 30.0, 50.0 -1.4
DBA/2HaSmnJ f 60.0 18.4   6 7.53 0.307 40.0, 80.0 -0.4
DBA/2HaSmnJ m 55.8 17.2   6 7.0 0.307 40.0, 80.0 -0.66
DBA/2J m 105.0 18.1   9 6.05 0.173 65.0, 119.0 1.28
IDH2/Ei f 65.6 11.3   9 3.77 0.172 50.0, 90.0 -0.16
LP/J f 117.0 2.19   5 0.98 0.0187 115.0, 119.0 1.99
MA/MyJ m 71.6 26.0   9 8.66 0.363 55.0, 119.0 -0.04
MOLD/RkJ f 50.8 24.6   6 10.0 0.484 35.0, 95.0 -0.78
NOD/ShiLtJ m 112.0 14.5   9 4.82 0.129 75.0, 119.0 1.55
NON/ShiLtJ f 41.7 2.58   6 1.05 0.062 40.0, 45.0 -1.16
NON/ShiLtJ m 38.0 2.74   5 1.22 0.0721 35.0, 40.0 -1.36
P/J f 58.3 19.7   6 8.03 0.337 40.0, 95.0 -0.47
SENCARA/PtJ f 75.0 28.1   5 12.5 0.374 50.0, 105.0 0.23
SKH2/J f 117.0 4.02   5 1.8 0.0343 110.0, 119.0 1.99
SWR/J f 45.0 9.13   7 3.45 0.203 35.0, 60.0 -1.03
SWR/J m 42.0 7.58   5 3.39 0.181 35.0, 55.0 -1.2
YBR/EiJ f 55.0 18.2   6 7.42 0.33 35.0, 85.0 -0.61
YBR/EiJ m 45.0 3.78   8 1.34 0.084 40.0, 50.0 -1.08


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129P3/J f 84.8889 5.492 95.6914 74.0864
129P3/J m 84.4444 5.492 95.247 73.6419
A/HeJ f 61.0465 2.5126 65.9886 56.1044
A/HeJ m 59.2308 4.5696 68.219 50.2425
A/J f 94.7778 3.8834 102.4163 87.1392
A/J m 112.0526 3.7798 119.4874 104.6178
A/WySnJ f 72.381 2.5423 77.3815 67.3804
A/WySnJ m 73.9583 3.3631 80.5735 67.3432
C57BL/6J f 74.2353 3.996 82.0953 66.3753
C57BL/6J m 86.4348 3.4355 93.1922 79.6773
C57BR/cdJ f 95.125 4.119 103.2269 87.0231
C57BR/cdJ m 83.1818 4.9677 92.9531 73.4106
C57L/J f 99.4091 3.5127 106.3184 92.4998
C57L/J m 88.8889 5.492 99.6914 78.0864
CAST/EiJ f 45.0 6.7263 58.2303 31.7697
CAST/EiJ m 43.3333 5.492 54.1358 32.5308
CBA/CaJ f 40.5882 3.996 48.4482 32.7283
CBA/CaJ m 37.0 5.2101 47.2482 26.7518
DBA/2HaSmnJ f 60.0 6.7263 73.2303 46.7697
DBA/2HaSmnJ m 55.8333 6.7263 69.0637 42.603
NON/ShiLtJ f 41.6667 6.7263 54.897 28.4363
NON/ShiLtJ m 38.0 7.3682 52.4931 23.5069
SWR/J f 45.0 6.2273 57.2489 32.7511
SWR/J m 42.0 7.3682 56.4931 27.5069
YBR/EiJ f 55.0 6.7263 68.2303 41.7697
YBR/EiJ m 45.0 5.8251 56.4578 33.5422


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129P3/J both 84.6667 3.8834 92.3052 77.0281
A/HeJ both 60.1386 2.6074 65.2673 55.01
A/J both 103.4152 2.7096 108.7449 98.0855
A/WySnJ both 73.1696 2.108 77.3159 69.0234
C57BL/6J both 80.335 2.6349 85.5178 75.1523
C57BR/cdJ both 89.1534 3.2266 95.5 82.8068
C57L/J both 94.149 3.2596 100.5606 87.7374
CAST/EiJ both 44.1667 4.3418 52.7068 35.6265
CBA/CaJ both 38.7941 3.283 45.2518 32.3365
DBA/2HaSmnJ both 57.9167 4.7562 67.2719 48.5614
NON/ShiLtJ both 39.8333 4.9883 49.6452 30.0215
SWR/J both 43.5 4.8237 52.988 34.012
YBR/EiJ both 50.0 4.449 58.751 41.249




  GWAS USING LINEAR MIXED MODELS