Project measure / variable:   Johnson1   pip8kHz_old

ID, description, units MPD:1408   pip8kHz_old   auditory brainstem response (ABR) threshold, 15-72 wk old group, sound pressure level   [dB]  8kHz pip stimulus  
Data set, strains Johnson1   inbred   27 strains     sex: both     age: 15-72wks
Procedure ABR test
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  STRAIN COMPARISON PLOT
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Johnson1 - auditory brainstem response (ABR) threshold, 15-72 wk old group, sound pressure level 8kHz pip stimulus



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested21 strains19 strains
Mean of the strain means51.7   dB 56.3   dB
Median of the strain means47.5   dB 49.4   dB
SD of the strain means± 22.6 ± 22.7
Coefficient of variation (CV)0.438 0.403
Min–max range of strain means24.2   –   99.6   dB 25.5   –   96.6   dB
Mean sample size per strain11.4   mice 10.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 694.1863 694.1863 2.5166 0.1136
strain 12 114594.4713 9549.5393 34.6197 < 0.0001
sex:strain 12 5900.9479 491.7457 1.7827 0.0497
Residuals 340 93786.113 275.8415


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129P3/J f 63.8 23.1   9 7.69 0.362 40.0, 104.0 0.54
129P3/J m 62.2 12.5   9 4.18 0.201 45.0, 85.0 0.26
129T2/SvEmsJ m 47.5 6.12   6 2.5 0.129 40.0, 55.0 -0.39
129X1/SvJ m 49.4 18.8   8 6.64 0.381 30.0, 75.0 -0.3
A/HeJ f 43.6 5.49   43 0.837 0.126 25.0, 55.0 -0.36
A/HeJ m 43.1 9.47   13 2.63 0.22 25.0, 65.0 -0.58
A/J f 77.6 30.1   18 7.1 0.388 25.0, 104.0 1.15
A/J m 92.9 16.0   19 3.68 0.173 50.0, 104.0 1.62
A/WySnJ f 53.1 12.3   42 1.9 0.232 25.0, 85.0 0.06
A/WySnJ m 55.8 14.0   24 2.87 0.251 40.0, 90.0 -0.02
BUB/BnJ m 91.1 10.3   7 3.88 0.113 80.0, 104.0 1.54
C3H/HeJ f 24.2 6.65   6 2.71 0.275 15.0, 35.0 -1.22
C57BL/6J f 54.8 30.2   17 7.31 0.55 25.0, 104.0 0.14
C57BL/6J m 67.8 30.5   23 6.36 0.45 30.0, 104.0 0.51
C57BLKS/J f 37.9 8.59   7 3.25 0.227 25.0, 50.0 -0.61
C57BR/cdJ f 77.1 17.2   16 4.3 0.223 35.0, 104.0 1.12
C57BR/cdJ m 63.2 15.5   11 4.68 0.246 40.0, 90.0 0.31
C57L/J f 77.9 13.8   22 2.93 0.177 55.0, 104.0 1.16
C57L/J m 70.6 6.82   9 2.27 0.0967 55.0, 75.0 0.63
CAST/EiJ f 38.3 12.1   6 4.94 0.316 25.0, 60.0 -0.59
CAST/EiJ m 29.4 19.8   9 6.59 0.671 15.0, 75.0 -1.18
CBA/CaJ f 25.6 6.82   17 1.65 0.267 15.0, 45.0 -1.15
CBA/CaJ m 25.5 7.62   10 2.41 0.299 15.0, 35.0 -1.36
DBA/2HaSmnJ f 35.8 14.3   6 5.83 0.399 20.0, 50.0 -0.7
DBA/2HaSmnJ m 38.3 12.9   6 5.27 0.337 30.0, 55.0 -0.79
DBA/2J m 85.2 20.8   9 6.93 0.244 40.0, 104.0 1.28
IDH2/Ei f 48.9 12.4   9 4.15 0.255 35.0, 65.0 -0.12
LP/J f 97.6 6.19   5 2.77 0.0634 90.0, 104.0 2.03
MA/MyJ m 45.4 29.6   9 9.86 0.651 25.0, 104.0 -0.48
MOLD/RkJ f 29.2 9.7   6 3.96 0.333 20.0, 45.0 -0.99
NOD/ShiLtJ m 96.6 14.6   9 4.88 0.152 60.0, 104.0 1.78
NON/ShiLtJ f 28.3 4.08   6 1.67 0.144 25.0, 35.0 -1.03
NON/ShiLtJ m 30.0 5.0   5 2.24 0.167 25.0, 35.0 -1.16
P/J f 44.2 17.4   6 7.12 0.395 30.0, 75.0 -0.33
SENCARA/PtJ f 48.0 25.9   5 11.6 0.539 25.0, 85.0 -0.16
SKH2/J f 99.6 5.73   5 2.56 0.0575 90.0, 104.0 2.12
SWR/J f 32.1 3.93   7 1.49 0.122 25.0, 35.0 -0.87
SWR/J m 35.0 7.07   5 3.16 0.202 25.0, 40.0 -0.94
YBR/EiJ f 47.5 16.0   6 6.55 0.338 35.0, 75.0 -0.18
YBR/EiJ m 40.0 4.63   8 1.64 0.116 30.0, 45.0 -0.72


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129P3/J f 63.7778 5.5362 74.6672 52.8883
129P3/J m 62.2222 5.5362 73.1117 51.3328
A/HeJ f 43.6047 2.5328 48.5865 38.6228
A/HeJ m 43.0769 4.6064 52.1375 34.0164
A/J f 77.5556 3.9147 85.2555 69.8556
A/J m 92.8947 3.8102 100.3894 85.4001
A/WySnJ f 53.0952 2.5627 58.1361 48.0544
A/WySnJ m 55.8333 3.3902 62.5017 49.1649
C57BL/6J f 54.8235 4.0281 62.7468 46.9003
C57BL/6J m 67.7826 3.4631 74.5944 60.9708
C57BR/cdJ f 77.125 4.1521 85.2921 68.9579
C57BR/cdJ m 63.1818 5.0076 73.0317 53.332
C57L/J f 77.8636 3.5409 84.8285 70.8987
C57L/J m 70.5556 5.5362 81.445 59.6661
CAST/EiJ f 38.3333 6.7804 51.6701 24.9966
CAST/EiJ m 29.4444 5.5362 40.3339 18.555
CBA/CaJ f 25.5882 4.0281 33.5115 17.665
CBA/CaJ m 25.5 5.2521 35.8306 15.1694
DBA/2HaSmnJ f 35.8333 6.7804 49.1701 22.4966
DBA/2HaSmnJ m 38.3333 6.7804 51.6701 24.9966
NON/ShiLtJ f 28.3333 6.7804 41.6701 14.9966
NON/ShiLtJ m 30.0 7.4275 44.6097 15.3903
SWR/J f 32.1429 6.2774 44.4903 19.7954
SWR/J m 35.0 7.4275 49.6097 20.3903
YBR/EiJ f 47.5 6.7804 60.8368 34.1632
YBR/EiJ m 40.0 5.872 51.55 28.45


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129P3/J both 63.0 3.9147 70.7 55.3
A/HeJ both 43.3408 2.6284 48.5107 38.1709
A/J both 85.2251 2.7314 90.5977 79.8525
A/WySnJ both 54.4643 2.1249 58.6439 50.2847
C57BL/6J both 61.3031 2.6561 66.5275 56.0786
C57BR/cdJ both 70.1534 3.2526 76.5511 63.7557
C57L/J both 74.2096 3.2859 80.6728 67.7464
CAST/EiJ both 33.8889 4.3767 42.4977 25.28
CBA/CaJ both 25.5441 3.3095 32.0537 19.0345
DBA/2HaSmnJ both 37.0833 4.7945 46.5139 27.6528
NON/ShiLtJ both 29.1667 5.0285 39.0575 19.2758
SWR/J both 33.5714 4.8625 43.1357 24.0071
YBR/EiJ both 43.75 4.4848 52.5715 34.9285




  GWAS USING LINEAR MIXED MODELS