Project measure / variable:   Johnson1   click_old

ID, description, units MPD:1407   click_old   auditory brainstem response (ABR) threshold, 15-72 wk old group, sound pressure level   [dB]  click stimulus  
Data set, strains Johnson1   inbred   27 strains     sex: both     age: 15-72wks
Procedure ABR test
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  STRAIN COMPARISON PLOT
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Johnson1 - auditory brainstem response (ABR) threshold, 15-72 wk old group, sound pressure level click stimulus



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested21 strains19 strains
Mean of the strain means61.1   dB 64.7   dB
Median of the strain means51.1   dB 58.8   dB
SD of the strain means± 25.4 ± 25.4
Coefficient of variation (CV)0.416 0.392
Min–max range of strain means35.8   –   118   dB 35.0   –   108   dB
Mean sample size per strain11.4   mice 10.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 926.3929 926.3929 2.6238 0.1062
strain 12 148994.7802 12416.2317 35.166 < 0.0001
sex:strain 12 8658.7977 721.5665 2.0437 0.0202
Residuals 340 120045.5182 353.0751


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129P3/J f 79.6 27.1   9 9.04 0.341 45.0, 119.0 0.73
129P3/J m 82.2 12.8   9 4.26 0.155 65.0, 105.0 0.69
129T2/SvEmsJ m 46.7 6.83   6 2.79 0.146 40.0, 55.0 -0.71
129X1/SvJ m 61.9 22.2   8 7.85 0.359 40.0, 90.0 -0.11
A/HeJ f 45.1 6.59   43 1.01 0.146 35.0, 70.0 -0.63
A/HeJ m 45.8 5.72   13 1.59 0.125 40.0, 60.0 -0.74
A/J f 91.3 30.3   18 7.14 0.332 45.0, 119.0 1.19
A/J m 108.0 16.7   19 3.82 0.154 65.0, 119.0 1.71
A/WySnJ f 59.2 19.3   42 2.97 0.325 40.0, 110.0 -0.08
A/WySnJ m 54.8 18.6   24 3.79 0.339 40.0, 95.0 -0.39
BUB/BnJ m 106.0 9.42   7 3.56 0.0888 95.0, 119.0 1.63
C3H/HeJ f 36.7 4.08   6 1.67 0.111 30.0, 40.0 -0.96
C57BL/6J f 65.4 34.7   17 8.43 0.531 35.0, 119.0 0.17
C57BL/6J m 80.6 35.5   23 7.41 0.441 35.0, 119.0 0.63
C57BLKS/J f 50.7 12.4   7 4.68 0.244 35.0, 65.0 -0.41
C57BR/cdJ f 84.0 18.9   16 4.72 0.225 40.0, 119.0 0.9
C57BR/cdJ m 65.5 15.7   11 4.74 0.24 45.0, 90.0 0.03
C57L/J f 87.2 15.6   22 3.32 0.179 60.0, 119.0 1.03
C57L/J m 76.7 7.5   9 2.5 0.0978 60.0, 85.0 0.47
CAST/EiJ f 35.8 4.92   6 2.01 0.137 30.0, 45.0 -0.99
CAST/EiJ m 38.9 18.0   9 6.0 0.463 30.0, 85.0 -1.02
CBA/CaJ f 36.5 3.43   17 0.832 0.094 30.0, 45.0 -0.97
CBA/CaJ m 36.5 4.12   10 1.3 0.113 30.0, 45.0 -1.11
DBA/2HaSmnJ f 47.5 12.1   6 4.96 0.256 35.0, 60.0 -0.54
DBA/2HaSmnJ m 44.2 14.3   6 5.83 0.324 35.0, 65.0 -0.81
DBA/2J m 97.4 21.1   9 7.05 0.217 55.0, 119.0 1.29
IDH2/Ei f 51.1 15.0   9 4.98 0.293 40.0, 90.0 -0.39
LP/J f 118.0 1.79   5 0.8 0.0151 115.0, 119.0 2.24
MA/MyJ m 58.8 28.4   9 9.48 0.484 40.0, 119.0 -0.23
MOLD/RkJ f 38.3 4.08   6 1.67 0.106 35.0, 45.0 -0.9
NOD/ShiLtJ m 105.0 16.1   9 5.38 0.154 80.0, 119.0 1.59
NON/ShiLtJ f 37.5 2.74   6 1.12 0.073 35.0, 40.0 -0.93
NON/ShiLtJ m 35.0 0.0   5 0.0 0.0 35.0, 35.0 -1.17
P/J f 54.2 18.8   6 7.68 0.347 35.0, 80.0 -0.27
SENCARA/PtJ f 60.0 22.6   5 10.1 0.377 40.0, 95.0 -0.04
SKH2/J f 116.0 1.79   5 0.8 0.0154 115.0, 119.0 2.16
SWR/J f 39.3 4.5   7 1.7 0.115 35.0, 45.0 -0.86
SWR/J m 44.0 8.94   5 4.0 0.203 35.0, 55.0 -0.81
YBR/EiJ f 50.0 14.8   6 6.06 0.297 35.0, 75.0 -0.44
YBR/EiJ m 40.6 3.2   8 1.13 0.0789 35.0, 45.0 -0.95


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129P3/J f 79.5556 6.2634 91.8755 67.2356
129P3/J m 82.2222 6.2634 94.5422 69.9023
A/HeJ f 45.1163 2.8655 50.7526 39.48
A/HeJ m 45.7692 5.2115 56.0201 35.5184
A/J f 91.2778 4.4289 99.9893 82.5663
A/J m 108.3684 4.3108 116.8476 99.8892
A/WySnJ f 59.1667 2.8994 64.8697 53.4636
A/WySnJ m 54.7917 3.8356 62.3361 47.2473
C57BL/6J f 65.4118 4.5573 74.3758 56.4477
C57BL/6J m 80.6087 3.918 88.3154 72.902
C57BR/cdJ f 84.0 4.6976 93.24 74.76
C57BR/cdJ m 65.4545 5.6655 76.5984 54.3107
C57L/J f 87.1818 4.0061 95.0617 79.3019
C57L/J m 76.6667 6.2634 88.9866 64.3467
CAST/EiJ f 35.8333 7.6711 50.9221 20.7445
CAST/EiJ m 38.8889 6.2634 51.2088 26.5689
CBA/CaJ f 36.4706 4.5573 45.4347 27.5065
CBA/CaJ m 36.5 5.942 48.1877 24.8123
DBA/2HaSmnJ f 47.5 7.6711 62.5888 32.4112
DBA/2HaSmnJ m 44.1667 7.6711 59.2555 29.0779
NON/ShiLtJ f 37.5 7.6711 52.5888 22.4112
NON/ShiLtJ m 35.0 8.4033 51.529 18.471
SWR/J f 39.2857 7.1021 53.2552 25.3162
SWR/J m 44.0 8.4033 60.529 27.471
YBR/EiJ f 50.0 7.6711 65.0888 34.9112
YBR/EiJ m 40.625 6.6434 53.6923 27.5577


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129P3/J both 80.8889 4.4289 89.6004 72.1774
A/HeJ both 45.4428 2.9737 51.2918 39.5937
A/J both 99.8231 3.0902 105.9015 93.7447
A/WySnJ both 56.9792 2.4041 61.7079 52.2505
C57BL/6J both 73.0102 3.005 78.921 67.0995
C57BR/cdJ both 74.7273 3.6798 81.9654 67.4892
C57L/J both 81.9242 3.7175 89.2365 74.612
CAST/EiJ both 37.3611 4.9517 47.1009 27.6213
CBA/CaJ both 36.4853 3.7442 43.85 29.1205
DBA/2HaSmnJ both 45.8333 5.4243 56.5027 35.1639
NON/ShiLtJ both 36.25 5.689 47.4402 25.0598
SWR/J both 41.6429 5.5012 52.4636 30.8221
YBR/EiJ both 45.3125 5.074 55.2928 35.3322




  GWAS USING LINEAR MIXED MODELS