Project measure / variable:   Johnson1   pip32kHz_yng

ID, description, units MPD:1405   pip32kHz_yng   auditory brainstem response (ABR) threshold, 3-12 wk old group, sound pressure level   [dB]  32kHz pip stimulus  
Data set, strains Johnson1   inbred   42 strains     sex: both     age: 3-12wks
Procedure ABR test
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  STRAIN COMPARISON PLOT
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Johnson1 - auditory brainstem response (ABR) threshold, 3-12 wk old group, sound pressure level 32kHz pip stimulus



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested26 strains28 strains
Mean of the strain means61.5   dB 61.2   dB
Median of the strain means55.4   dB 57.5   dB
SD of the strain means± 21.0 ± 20.3
Coefficient of variation (CV)0.342 0.331
Min–max range of strain means35.0   –   110   dB 36.0   –   102   dB
Mean sample size per strain7.2   mice 6.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1840.2804 1840.2804 7.2886 0.0076
strain 11 84986.5799 7726.0527 30.5996 < 0.0001
sex:strain 11 9596.3516 872.3956 3.4552 0.0002
Residuals 179 45195.5073 252.4889


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129P1/ReJ f 65.0 10.6   9 3.54 0.163 50.0, 85.0 0.17
129P1/ReJ m 65.6 11.5   8 4.06 0.175 45.0, 80.0 0.22
129P3/J f 69.0 7.42   5 3.32 0.107 60.0, 80.0 0.36
129T2/SvEmsJ f 42.0 4.47   5 2.0 0.106 35.0, 45.0 -0.93
A/HeJ f 55.0 3.69   12 1.07 0.0671 50.0, 60.0 -0.31
A/J f 59.3 19.7   7 7.43 0.332 40.0, 85.0 -0.1
A/J m 96.3 27.4   19 6.29 0.285 45.0, 119.0 1.74
ALR/LtJ m 98.0 8.37   5 3.74 0.0854 90.0, 110.0 1.82
ALS/LtJ m 86.7 10.3   6 4.22 0.119 70.0, 100.0 1.26
A/WySnJ f 52.9 12.0   12 3.45 0.226 35.0, 70.0 -0.41
A/WySnJ m 63.2 12.7   11 3.83 0.201 40.0, 80.0 0.1
BPN/3J m 66.7 8.16   6 3.33 0.122 55.0, 75.0 0.27
BUB/BnJ f 103.0 17.8   11 5.36 0.173 65.0, 119.0 1.98
BUB/BnJ m 83.4 22.4   7 8.47 0.269 60.0, 119.0 1.1
C3H/HeOuJ m 41.0 2.24   5 1.0 0.0545 40.0, 45.0 -1.0
C57BL/6J m 64.0 13.4   5 6.0 0.21 50.0, 85.0 0.14
C57BLKS/J m 66.0 16.7   5 7.48 0.254 40.0, 80.0 0.24
C58/J f 49.0 4.18   5 1.87 0.0854 45.0, 55.0 -0.6
CBA/CaJ f 41.1 4.86   9 1.62 0.118 35.0, 50.0 -0.97
CBA/CaJ m 37.0 4.47   5 2.0 0.121 30.0, 40.0 -1.19
CE/J m 45.0 3.16   6 1.29 0.0703 40.0, 50.0 -0.8
DBA/1J f 57.0 4.47   5 2.0 0.0785 50.0, 60.0 -0.21
DBA/1J m 49.0 4.18   5 1.87 0.0854 45.0, 55.0 -0.6
DBA/1LacJ m 49.0 6.52   5 2.92 0.133 45.0, 60.0 -0.6
DBA/2HaSmnJ m 57.0 13.5   5 6.04 0.237 45.0, 80.0 -0.21
DBA/2J f 64.3 17.7   7 6.68 0.275 40.0, 85.0 0.13
DBA/2J m 64.3 10.5   14 2.82 0.164 50.0, 80.0 0.16
FVB/NJ f 37.0 2.74   5 1.22 0.074 35.0, 40.0 -1.17
I/LnJ f 57.5 17.9   8 6.34 0.312 45.0, 100.0 -0.19
JF1/MsJ f 110.0 13.4   9 4.46 0.122 80.0, 119.0 2.31
JF1/MsJ m 102.0 19.7   10 6.23 0.192 70.0, 119.0 2.02
LG/J m 44.0 4.18   5 1.87 0.0951 40.0, 50.0 -0.85
LP/J f 52.9 8.59   7 3.25 0.163 45.0, 65.0 -0.41
MA/MyJ f 52.0 22.0   5 9.82 0.422 35.0, 90.0 -0.45
MRL/MpJ m 58.0 14.4   5 6.44 0.248 40.0, 70.0 -0.16
MSM/MsJ f 46.0 2.24   5 1.0 0.0486 45.0, 50.0 -0.74
NOD.NON-H2nb1/LtJ f 64.0 8.94   5 4.0 0.14 50.0, 70.0 0.12
NOD.NON-H2nb1/LtJ m 70.0 12.7   5 5.7 0.182 55.0, 85.0 0.44
NOD/ShiLtJ f 96.1 20.2   7 7.63 0.21 80.0, 119.0 1.65
NOD/ShiLtJ m 98.2 21.4   6 8.74 0.218 60.0, 119.0 1.83
NON/ShiLtJ f 35.0 3.54   5 1.58 0.101 30.0, 40.0 -1.26
NOR/LtJ f 100.0 13.7   5 6.12 0.137 80.0, 115.0 1.83
PERA/EiJ m 46.9 9.61   8 3.4 0.205 35.0, 60.0 -0.7
P/J m 45.6 9.04   8 3.2 0.198 35.0, 60.0 -0.77
PL/J f 47.0 7.89   10 2.49 0.168 40.0, 60.0 -0.69
PWK/PhJ f 52.1 3.93   7 1.49 0.0754 50.0, 60.0 -0.45
RIIIS/J m 36.0 2.24   5 1.0 0.0621 35.0, 40.0 -1.24
SEC/1ReJ m 42.0 2.74   5 1.22 0.0652 40.0, 45.0 -0.95
SENCARA/PtJ f 46.2 5.83   13 1.62 0.126 40.0, 60.0 -0.73
SENCARA/PtJ m 47.0 9.08   5 4.06 0.193 35.0, 55.0 -0.7
SJL/J m 38.3 5.16   6 2.11 0.135 30.0, 45.0 -1.13
SKH2/J f 90.0 25.7   5 11.5 0.286 50.0, 115.0 1.36
WSB/EiJ f 55.7 16.4   7 6.21 0.295 35.0, 80.0 -0.28
WSB/EiJ m 52.1 15.5   7 5.86 0.297 35.0, 75.0 -0.45


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129P1/ReJ f 65.0 5.2966 75.4519 54.5481
129P1/ReJ m 65.625 5.6179 76.7109 54.5391
A/J f 59.2857 6.0058 71.137 47.4344
A/J m 96.2632 3.6454 103.4566 89.0697
A/WySnJ f 52.9167 4.587 61.9683 43.8651
A/WySnJ m 63.1818 4.791 72.6359 53.7277
BUB/BnJ f 102.9091 4.791 112.3632 93.455
BUB/BnJ m 83.4286 6.0058 95.2799 71.5773
CBA/CaJ f 41.1111 5.2966 51.563 30.6592
CBA/CaJ m 37.0 7.1062 51.0227 22.9773
DBA/1J f 57.0 7.1062 71.0227 42.9773
DBA/1J m 49.0 7.1062 63.0227 34.9773
DBA/2J f 64.2857 6.0058 76.137 52.4344
DBA/2J m 64.2857 4.2468 72.6659 55.9056
JF1/MsJ f 110.0 5.2966 120.4519 99.5481
JF1/MsJ m 102.5 5.0248 112.4155 92.5845
NOD.NON-H2nb1/LtJ f 64.0 7.1062 78.0227 49.9773
NOD.NON-H2nb1/LtJ m 70.0 7.1062 84.0227 55.9773
NOD/ShiLtJ f 96.1429 6.0058 107.9942 84.2915
NOD/ShiLtJ m 98.1667 6.487 110.9675 85.3658
SENCARA/PtJ f 46.1538 4.4071 54.8503 37.4574
SENCARA/PtJ m 47.0 7.1062 61.0227 32.9773
WSB/EiJ f 55.7143 6.0058 67.5656 43.863
WSB/EiJ m 52.1429 6.0058 63.9942 40.2915


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129P1/ReJ both 65.3125 3.8606 72.9305 57.6945
A/J both 77.7744 3.5128 84.7062 70.8426
A/WySnJ both 58.0492 3.3164 64.5935 51.505
BUB/BnJ both 93.1688 3.8413 100.749 85.5887
CBA/CaJ both 39.0556 4.4315 47.8002 30.3109
DBA/1J both 53.0 5.0248 62.9155 43.0845
DBA/2J both 64.2857 3.6778 71.5431 57.0283
JF1/MsJ both 106.25 3.6505 113.4535 99.0465
NOD.NON-H2nb1/LtJ both 67.0 5.0248 76.9155 57.0845
NOD/ShiLtJ both 97.1548 4.4202 105.8771 88.4324
SENCARA/PtJ both 46.5769 4.1809 54.8271 38.3267
WSB/EiJ both 53.9286 4.2468 62.3087 45.5484




  GWAS USING LINEAR MIXED MODELS