Project measure / variable:   Johnson1   pip16kHz_yng

ID, description, units MPD:1404   pip16kHz_yng   auditory brainstem response (ABR) threshold, 3-12 wk old group, sound pressure level   [dB]  16kHz pip stimulus  
Data set, strains Johnson1   inbred   42 strains     sex: both     age: 3-12wks
Procedure ABR test
Ontology mappings

  STRAIN COMPARISON PLOT
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Johnson1 - auditory brainstem response (ABR) threshold, 3-12 wk old group, sound pressure level 16kHz pip stimulus

NOR/LtJALR/LtJNOD/ShiLtJJF1/MsJBUB/BnJSKH2/JALS/LtJA/JDBA/2JNOD.NON-H2<nb1>/LtJC57BLKS/JBPN/3JC57BL/6J129P1/ReJ129P3/JMA/MyJI/LnJDBA/2HaSmnJPL/JDBA/1JC58/JMRL/MpJA/WySnJWSB/EiJLP/JCE/JLG/JSEC/1ReJSENCARA/PtJDBA/1LacJPERA/EiJFVB/NJP/JC3H/HeOuJRIIIS/JPWK/PhJ129T2/SvEmsJA/HeJCBA/CaJMSM/MsJNON/ShiLtJSJL/J dB 102030405060708090100femalemale


  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested26 strains28 strains
Mean of the strain means34.3   dB 36.0   dB
Median of the strain means23.2   dB 23.5   dB
SD of the strain means± 23.5 ± 23.1
Coefficient of variation (CV)0.686 0.643
Min–max range of strain means13.0   –   82.7   dB 12.5   –   83.2   dB
Mean sample size per strain7.2   mice 6.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 4395.1637 4395.1637 16.3032 0.0001
strain 11 115495.2045 10499.564 38.9464 < 0.0001
sex:strain 11 3425.0356 311.3669 1.155 0.3217
Residuals 179 48256.5766 269.5898


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain
Sex
Mean
SD
N mice
SEM
CV
Min, Max
Z score
129P1/ReJ f 31.7 9.01   9 3.0 0.285 20.0, 45.0 -0.11
129P1/ReJ m 36.2 10.3   8 3.63 0.283 20.0, 50.0 0.01
129P3/J f 33.0 12.0   5 5.39 0.365 20.0, 50.0 -0.06
129T2/SvEmsJ f 15.0 5.0   5 2.24 0.333 10.0, 20.0 -0.82
A/HeJ f 15.0 0.0   12 0.0 0.0 15.0, 15.0 -0.82
A/J f 57.1 6.36   7 2.4 0.111 50.0, 65.0 0.97
A/J m 73.1 24.5   19 5.62 0.335 25.0, 99.0 1.61
ALR/LtJ m 80.0 7.07   5 3.16 0.0884 70.0, 90.0 1.91
ALS/LtJ m 65.8 14.3   6 5.83 0.217 50.0, 90.0 1.29
A/WySnJ f 16.2 3.77   12 1.09 0.232 10.0, 20.0 -0.77
A/WySnJ m 26.4 12.5   11 3.76 0.473 15.0, 60.0 -0.41
BPN/3J m 39.2 21.5   6 8.8 0.55 20.0, 75.0 0.14
BUB/BnJ f 75.8 13.8   11 4.15 0.181 50.0, 99.0 1.76
BUB/BnJ m 68.4 17.9   7 6.77 0.262 50.0, 99.0 1.4
C3H/HeOuJ m 16.0 2.24   5 1.0 0.14 15.0, 20.0 -0.86
C57BL/6J m 38.0 21.1   5 9.43 0.555 15.0, 70.0 0.09
C57BLKS/J m 42.0 14.8   5 6.63 0.353 20.0, 55.0 0.26
C58/J f 22.0 5.7   5 2.55 0.259 15.0, 30.0 -0.52
CBA/CaJ f 13.3 3.54   9 1.18 0.265 10.0, 20.0 -0.89
CBA/CaJ m 13.0 2.74   5 1.22 0.211 10.0, 15.0 -0.99
CE/J m 20.0 3.16   6 1.29 0.158 15.0, 25.0 -0.69
DBA/1J f 23.0 7.58   5 3.39 0.33 15.0, 30.0 -0.48
DBA/1J m 21.0 7.42   5 3.32 0.353 10.0, 30.0 -0.65
DBA/1LacJ m 18.0 6.71   5 3.0 0.373 15.0, 30.0 -0.78
DBA/2HaSmnJ m 25.0 14.1   5 6.32 0.566 15.0, 50.0 -0.47
DBA/2J f 43.6 25.1   7 9.49 0.576 10.0, 75.0 0.39
DBA/2J m 55.4 17.8   14 4.76 0.322 15.0, 75.0 0.84
FVB/NJ f 17.0 2.74   5 1.22 0.161 15.0, 20.0 -0.74
I/LnJ f 25.6 15.5   8 5.46 0.603 15.0, 60.0 -0.37
JF1/MsJ f 82.7 25.4   9 8.46 0.307 35.0, 99.0 2.06
JF1/MsJ m 72.5 28.6   10 9.03 0.394 30.0, 99.0 1.58
LG/J m 20.0 3.54   5 1.58 0.177 15.0, 25.0 -0.69
LP/J f 20.0 8.66   7 3.27 0.433 10.0, 35.0 -0.61
MA/MyJ f 32.0 18.6   5 8.31 0.58 15.0, 60.0 -0.1
MRL/MpJ m 22.0 5.7   5 2.55 0.259 15.0, 30.0 -0.6
MSM/MsJ f 13.0 2.74   5 1.22 0.211 10.0, 15.0 -0.91
NOD.NON-H2nb1/LtJ f 38.0 11.5   5 5.15 0.303 20.0, 50.0 0.16
NOD.NON-H2nb1/LtJ m 52.0 5.7   5 2.55 0.11 45.0, 60.0 0.69
NOD/ShiLtJ f 74.9 17.8   7 6.73 0.238 55.0, 99.0 1.72
NOD/ShiLtJ m 83.2 15.2   6 6.19 0.182 60.0, 99.0 2.04
NON/ShiLtJ f 13.0 2.74   5 1.22 0.211 10.0, 15.0 -0.91
NOR/LtJ f 81.0 8.94   5 4.0 0.11 70.0, 90.0 1.98
PERA/EiJ m 17.5 9.64   8 3.41 0.551 10.0, 40.0 -0.8
P/J m 16.9 4.58   8 1.62 0.271 10.0, 25.0 -0.83
PL/J f 23.5 7.84   10 2.48 0.333 15.0, 40.0 -0.46
PWK/PhJ f 15.7 1.89   7 0.714 0.12 15.0, 20.0 -0.79
RIIIS/J m 16.0 2.24   5 1.0 0.14 15.0, 20.0 -0.86
SEC/1ReJ m 19.0 2.24   5 1.0 0.118 15.0, 20.0 -0.73
SENCARA/PtJ f 19.2 16.4   13 4.56 0.855 10.0, 70.0 -0.64
SENCARA/PtJ m 18.0 7.58   5 3.39 0.421 10.0, 25.0 -0.78
SJL/J m 12.5 2.74   6 1.12 0.219 10.0, 15.0 -1.02
SKH2/J f 69.0 21.6   5 9.67 0.313 35.0, 85.0 1.47
WSB/EiJ f 22.1 14.7   7 5.55 0.663 5.0, 45.0 -0.52
WSB/EiJ m 20.0 11.9   7 4.5 0.595 10.0, 45.0 -0.69


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129P1/ReJ f 31.6667 5.4731 42.4667 20.8666
129P1/ReJ m 36.25 5.8051 47.7052 24.7948
A/J f 57.1429 6.2059 69.3889 44.8968
A/J m 73.1053 3.7668 80.5384 65.6722
A/WySnJ f 16.25 4.7398 25.6031 6.8969
A/WySnJ m 26.3636 4.9506 36.1326 16.5946
BUB/BnJ f 75.8182 4.9506 85.5872 66.0492
BUB/BnJ m 68.4286 6.2059 80.6746 56.1825
CBA/CaJ f 13.3333 5.4731 24.1334 2.5333
CBA/CaJ m 13.0 7.3429 27.4898 0.0
DBA/1J f 23.0 7.3429 37.4898 8.5102
DBA/1J m 21.0 7.3429 35.4898 6.5102
DBA/2J f 43.5714 6.2059 55.8175 31.3254
DBA/2J m 55.3571 4.3882 64.0164 46.6979
JF1/MsJ f 82.6667 5.4731 93.4667 71.8666
JF1/MsJ m 72.5 5.1922 82.7458 62.2542
NOD.NON-H2nb1/LtJ f 38.0 7.3429 52.4898 23.5102
NOD.NON-H2nb1/LtJ m 52.0 7.3429 66.4898 37.5102
NOD/ShiLtJ f 74.8571 6.2059 87.1032 62.6111
NOD/ShiLtJ m 83.1667 6.7031 96.3939 69.9394
SENCARA/PtJ f 19.2308 4.5539 28.2169 10.2446
SENCARA/PtJ m 18.0 7.3429 32.4898 3.5102
WSB/EiJ f 22.1429 6.2059 34.3889 9.8968
WSB/EiJ m 20.0 6.2059 32.2461 7.7539


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129P1/ReJ both 33.9583 3.9891 41.8301 26.0865
A/J both 65.1241 3.6298 72.2868 57.9614
A/WySnJ both 21.3068 3.4269 28.0691 14.5445
BUB/BnJ both 72.1234 3.9693 79.956 64.2908
CBA/CaJ both 13.1667 4.5791 22.2026 4.1307
DBA/1J both 22.0 5.1922 32.2458 11.7542
DBA/2J both 49.4643 3.8003 56.9634 41.9651
JF1/MsJ both 77.5833 3.772 85.0267 70.1399
NOD.NON-H2nb1/LtJ both 45.0 5.1922 55.2458 34.7542
NOD/ShiLtJ both 79.0119 4.5674 88.0248 69.999
SENCARA/PtJ both 18.6154 4.3202 27.1404 10.0904
WSB/EiJ both 21.0714 4.3882 29.7307 12.4121




  GWAS USING LINEAR MIXED MODELS

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