Project measure / variable:   Johnson1   click_yng

ID, description, units MPD:1402   click_yng   auditory brainstem response (ABR) threshold, 3-12 wk old group, sound pressure level   [dB]  click stimulus  
Data set, strains Johnson1   inbred   28 strains     sex: both     age: 3-12wks
Procedure ABR test
Ontology mappings

  STRAIN COMPARISON PLOT
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Johnson1 - auditory brainstem response (ABR) threshold, 3-12 wk old group, sound pressure level click stimulus



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested26 strains28 strains
Mean of the strain means52.3   dB 53.3   dB
Median of the strain means44.6   dB 44.8   dB
SD of the strain means± 21.5 ± 21.3
Coefficient of variation (CV)0.410 0.400
Min–max range of strain means33.0   –   107   dB 34.2   –   100   dB
Mean sample size per strain7.2   mice 6.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 3249.1824 3249.1824 15.0988 0.0001
strain 11 111807.2614 10164.2965 47.233 < 0.0001
sex:strain 11 6849.7937 622.7085 2.8937 0.0016
Residuals 179 38519.9004 215.195


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129P1/ReJ f 53.9 11.1   9 3.71 0.206 40.0, 70.0 0.07
129P1/ReJ m 55.6 6.78   8 2.4 0.122 45.0, 65.0 0.11
129P3/J f 52.0 7.58   5 3.39 0.146 45.0, 60.0 -0.01
129T2/SvEmsJ f 41.0 4.18   5 1.87 0.102 35.0, 45.0 -0.53
A/HeJ f 39.6 1.44   12 0.417 0.0365 35.0, 40.0 -0.59
A/J f 58.6 19.1   7 7.21 0.326 40.0, 85.0 0.29
A/J m 94.4 30.5   19 7.0 0.323 40.0, 119.0 1.93
ALR/LtJ m 99.8 13.8   5 6.17 0.138 80.0, 119.0 2.18
ALS/LtJ m 76.7 10.3   6 4.22 0.135 60.0, 90.0 1.1
A/WySnJ f 39.2 3.59   12 1.04 0.0916 35.0, 45.0 -0.61
A/WySnJ m 45.9 6.25   11 1.89 0.136 35.0, 60.0 -0.35
BPN/3J m 48.3 8.16   6 3.33 0.169 40.0, 60.0 -0.23
BUB/BnJ f 104.0 10.3   11 3.1 0.099 85.0, 119.0 2.41
BUB/BnJ m 95.6 12.4   7 4.69 0.13 80.0, 119.0 1.99
C3H/HeOuJ m 35.0 0.0   5 0.0 0.0 35.0, 35.0 -0.86
C57BL/6J m 56.0 13.9   5 6.2 0.248 40.0, 75.0 0.13
C57BLKS/J m 49.0 8.94   5 4.0 0.183 40.0, 60.0 -0.2
C58/J f 40.0 0.0   5 0.0 0.0 40.0, 40.0 -0.57
CBA/CaJ f 35.0 3.54   9 1.18 0.101 30.0, 40.0 -0.81
CBA/CaJ m 37.0 2.74   5 1.22 0.074 35.0, 40.0 -0.76
CE/J m 40.8 3.76   6 1.54 0.0922 35.0, 45.0 -0.59
DBA/1J f 45.0 5.0   5 2.24 0.111 40.0, 50.0 -0.34
DBA/1J m 42.0 2.74   5 1.22 0.0652 40.0, 45.0 -0.53
DBA/1LacJ m 39.0 2.24   5 1.0 0.0573 35.0, 40.0 -0.67
DBA/2HaSmnJ m 47.0 18.6   5 8.31 0.395 35.0, 80.0 -0.29
DBA/2J f 55.0 14.1   7 5.35 0.257 40.0, 80.0 0.13
DBA/2J m 55.7 10.5   14 2.82 0.189 40.0, 70.0 0.11
FVB/NJ f 33.0 2.74   5 1.22 0.083 30.0, 35.0 -0.9
I/LnJ f 47.5 14.6   8 5.18 0.308 35.0, 80.0 -0.22
JF1/MsJ f 107.0 20.9   9 6.98 0.196 60.0, 119.0 2.55
JF1/MsJ m 100.0 21.8   10 6.9 0.218 60.0, 119.0 2.19
LG/J m 37.0 2.74   5 1.22 0.074 35.0, 40.0 -0.76
LP/J f 46.4 3.78   7 1.43 0.0814 40.0, 50.0 -0.28
MA/MyJ f 36.0 2.24   5 1.0 0.0621 35.0, 40.0 -0.76
MRL/MpJ m 41.0 4.18   5 1.87 0.102 35.0, 45.0 -0.58
MSM/MsJ f 35.0 0.0   5 0.0 0.0 35.0, 35.0 -0.81
NOD.NON-H2nb1/LtJ f 50.0 7.07   5 3.16 0.141 40.0, 55.0 -0.11
NOD.NON-H2nb1/LtJ m 59.0 9.62   5 4.3 0.163 50.0, 75.0 0.27
NOD/ShiLtJ f 73.6 15.7   7 5.95 0.214 55.0, 95.0 0.99
NOD/ShiLtJ m 73.3 12.9   6 5.27 0.176 55.0, 90.0 0.94
NON/ShiLtJ f 34.0 2.24   5 1.0 0.0658 30.0, 35.0 -0.85
NOR/LtJ f 85.0 12.2   5 5.48 0.144 65.0, 95.0 1.52
PERA/EiJ m 36.2 5.18   8 1.83 0.143 30.0, 45.0 -0.8
P/J m 40.6 6.78   8 2.4 0.167 35.0, 55.0 -0.6
PL/J f 41.0 5.16   10 1.63 0.126 35.0, 50.0 -0.53
PWK/PhJ f 38.6 2.44   7 0.922 0.0633 35.0, 40.0 -0.64
RIIIS/J m 35.0 3.54   5 1.58 0.101 30.0, 40.0 -0.86
SEC/1ReJ m 36.0 2.24   5 1.0 0.0621 35.0, 40.0 -0.81
SENCARA/PtJ f 36.5 2.4   13 0.666 0.0657 35.0, 40.0 -0.74
SENCARA/PtJ m 38.0 2.74   5 1.22 0.0721 35.0, 40.0 -0.72
SJL/J m 34.2 2.04   6 0.833 0.0597 30.0, 35.0 -0.9
SKH2/J f 89.0 25.3   5 11.3 0.285 45.0, 105.0 1.71
WSB/EiJ f 44.3 11.3   7 4.29 0.256 35.0, 60.0 -0.37
WSB/EiJ m 43.6 14.6   7 5.53 0.336 35.0, 65.0 -0.45


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129P1/ReJ f 53.8889 4.8898 63.538 44.2397
129P1/ReJ m 55.625 5.1865 65.8595 45.3905
A/J f 58.5714 5.5446 69.5125 47.6303
A/J m 94.4211 3.3654 101.0621 87.7801
A/WySnJ f 39.1667 4.2347 47.5231 30.8103
A/WySnJ m 45.9091 4.423 54.6371 37.1811
BUB/BnJ f 104.0 4.423 112.728 95.272
BUB/BnJ m 95.5714 5.5446 106.5125 84.6303
CBA/CaJ f 35.0 4.8898 44.6492 25.3508
CBA/CaJ m 37.0 6.5604 49.9457 24.0543
DBA/1J f 45.0 6.5604 57.9457 32.0543
DBA/1J m 42.0 6.5604 54.9457 29.0543
DBA/2J f 55.0 5.5446 65.9411 44.0589
DBA/2J m 55.7143 3.9206 63.4508 47.9778
JF1/MsJ f 106.5556 4.8898 116.2047 96.9064
JF1/MsJ m 100.0 4.6389 109.154 90.846
NOD.NON-H2nb1/LtJ f 50.0 6.5604 62.9457 37.0543
NOD.NON-H2nb1/LtJ m 59.0 6.5604 71.9457 46.0543
NOD/ShiLtJ f 73.5714 5.5446 84.5125 62.6303
NOD/ShiLtJ m 73.3333 5.9888 85.1511 61.5156
SENCARA/PtJ f 36.5385 4.0686 44.567 28.5099
SENCARA/PtJ m 38.0 6.5604 50.9457 25.0543
WSB/EiJ f 44.2857 5.5446 55.2268 33.3446
WSB/EiJ m 43.5714 5.5446 54.5125 32.6303


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129P1/ReJ both 54.7569 3.5641 61.7899 47.724
A/J both 76.4962 3.243 82.8957 70.0968
A/WySnJ both 42.5379 3.0617 48.5796 36.4962
BUB/BnJ both 99.7857 3.5463 106.7837 92.7878
CBA/CaJ both 36.0 4.0911 44.0731 27.9269
DBA/1J both 43.5 4.6389 52.654 34.346
DBA/2J both 55.3571 3.3953 62.0572 48.6571
JF1/MsJ both 103.2778 3.3701 109.928 96.6276
NOD.NON-H2nb1/LtJ both 54.5 4.6389 63.654 45.346
NOD/ShiLtJ both 73.4524 4.0807 81.5048 65.3999
SENCARA/PtJ both 37.2692 3.8598 44.8858 29.6527
WSB/EiJ both 43.9286 3.9206 51.6651 36.192




  GWAS USING LINEAR MIXED MODELS