Project measure / variable:   Lesage2   B_cells_pct

ID, description, units MPD:131926   B_cells_pct   percentage of splenic lymphocytes that are B cells (CD3-CD49b-B220+CD19+)   [%]  
Data set, strains Lesage2   CC w/par   76 strains     sex: both     age: 5-8wks
Procedure immune cell quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Lesage2 - percentage of splenic lymphocytes that are B cells (CD3-CD49b-B220+CD19+)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested47 strains64 strains
Mean of the strain means59.49   % 58.66   %
Median of the strain means59.73   % 57.67   %
SD of the strain means± 11.47 ± 9.8514
Coefficient of variation (CV)0.1928 0.1679
Min–max range of strain means24.6   –   84.3   % 26.0   –   83.35   %
Mean sample size per strain2.3   mice 2.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 10.2507 10.2507 0.9352 0.34
strain 11 4117.7632 374.3421 34.1542 < 0.0001
sex:strain 11 262.1425 23.8311 2.1743 0.0392
Residuals 36 394.573 10.9604


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 66.9 3.5355   2   2.5 0.0528 64.4, 69.4 0.65
129S1/SvImJ m 62.35 2.3335   2   1.65 0.0374 60.7, 64.0 0.37
A/J f 65.05 2.3335   2   1.65 0.0359 63.4, 66.7 0.48
A/J m 61.6 0.42426   2   0.3 0.0069 61.3, 61.9 0.3
C57BL/6J f 68.75 3.4857   4 1.7428 0.0507 65.3, 73.6 0.81
C57BL/6J m 63.0 0.0   1   0.0 0.0 63.0, 63.0 0.44
CAST/EiJ f 84.3 2.8284   2   2.0 0.0336 82.3, 86.3 2.16
CAST/EiJ m 83.35 2.8991   2   2.05 0.0348 81.3, 85.4 2.51
CC008/Geni m 73.6 0.84853   2   0.6 0.0115 73.0, 74.2 1.52
CC010/Geni f 24.6 1.5556   2   1.1 0.0632 23.5, 25.7 -3.04
CC010/Geni m 26.0 0.0   1   0.0 0.0 26.0, 26.0 -3.32
CC012/Geni f 70.9 3.3779   3 1.9502 0.0476 68.9, 74.8 0.99
CC012/Geni m 67.5 4.2042   5 1.8802 0.0623 63.9, 72.6 0.9
CC013/Geni m 44.567 2.1779   3 1.2574 0.0489 42.8, 47.0 -1.43
CC016/Geni m 52.6 1.0817   3 0.6245 0.0206 51.7, 53.8 -0.62
CC020/Geni f 54.6 0.0   1   0.0 0.0 54.6, 54.6 -0.43
CC020/Geni m 55.85 3.8891   2   2.75 0.0696 53.1, 58.6 -0.29
CC023/Geni m 66.63 1.3013   3 0.7513 0.0195 65.3, 67.9 0.81
CC024/Geni f 57.4 3.2527   2   2.3 0.0567 55.1, 59.7 -0.18
CC024/Geni m 55.6 0.0   1   0.0 0.0 55.6, 55.6 -0.31
CC025/Geni f 60.27 0.15275   3 0.08819 0.0025 60.1, 60.4 0.07
CC026/Geni m 55.6 0.88882   3 0.51316 0.016 54.9, 56.6 -0.31
CC027/Geni f 46.2 0.0   1   0.0 0.0 46.2, 46.2 -1.16
CC027/Geni m 43.75 3.7477   2   2.65 0.0857 41.1, 46.4 -1.51
CC030/Geni f 70.05 1.2021   2   0.85 0.0172 69.2, 70.9 0.92
CC031/Geni f 49.2 0.0   1   0.0 0.0 49.2, 49.2 -0.9
CC031/Geni m 49.05 0.21213   2   0.15 0.0043 48.9, 49.2 -0.98
CC032/Geni m 59.07 1.4224   3 0.82125 0.0241 58.1, 60.7 0.04
CC033/Geni f 63.07 1.5885   3 0.91712 0.0252 62.1, 64.9 0.31
CC038/Geni f 72.95 1.6263   2   1.15 0.0223 71.8, 74.1 1.17
CC038/Geni m 72.2 0.0   1   0.0 0.0 72.2, 72.2 1.37
CC042/Geni m 62.67 1.5275   3 0.88192 0.0244 61.0, 64.0 0.41
CC043/Geni m 54.27 0.87369   3 0.50442 0.0161 53.3, 55.0 -0.45
CC056/Geni f 58.7 0.0   1   0.0 0.0 58.7, 58.7 -0.07
CC056/Geni m 61.25 2.0506   2   1.45 0.0335 59.8, 62.7 0.26
CC061/Geni m 61.87 2.5929   3 1.497 0.0419 58.9, 63.7 0.33
CIV2_FE f 67.03 2.1197   3 1.2238 0.0316 65.1, 69.3 0.66
DET3_GA m 66.5 1.4107   3 0.81445 0.0212 65.2, 68.0 0.8
DONNELL_HA f 55.1 3.3941   2   2.4 0.0616 52.7, 57.5 -0.38
DONNELL_HA m 55.07 0.15275   3 0.08819 0.0028 54.9, 55.2 -0.36
FIV_AC m 37.75 3.2306   4 1.6153 0.0856 34.3, 40.7 -2.12
FUF_HE f 65.9 3.061   3 1.7673 0.0464 62.7, 68.8 0.56
GALASUPREME_CE m 69.8 1.8682   3 1.0786 0.0268 67.8, 71.5 1.13
GIT_GC f 39.7 0.0   1   0.0 0.0 39.7, 39.7 -1.73
GIT_GC m 40.9 1.4142   2   1.0 0.0346 39.9, 41.9 -1.8
HAX2_EF f 65.23 0.87369   3 0.50442 0.0134 64.5, 66.2 0.5
HAZ_FE f 48.8 0.0   1   0.0 0.0 48.8, 48.8 -0.93
HAZ_FE m 56.15 2.6163   2   1.85 0.0466 54.3, 58.0 -0.25
HIP_GA f 55.7 0.0   1   0.0 0.0 55.7, 55.7 -0.33
HIP_GA m 53.95 0.35355   2   0.25 0.0066 53.7, 54.2 -0.48
HOE_GC f 55.9 0.0   1   0.0 0.0 55.9, 55.9 -0.31
HOE_GC m 56.25 2.6163   2   1.85 0.0465 54.4, 58.1 -0.24
JUD_EF m 59.92 2.5369   4 1.2684 0.0423 56.3, 62.2 0.13
KAV_AF f 57.65 0.07071   2   0.05 0.0012 57.6, 57.7 -0.16
KAV_AF m 56.3 0.0   1   0.0 0.0 56.3, 56.3 -0.24
LAM_DC f 57.5 0.0   1   0.0 0.0 57.5, 57.5 -0.17
LAM_DC m 55.7 9.051   2   6.4 0.1625 49.3, 62.1 -0.3
LAT_HD f 54.98 4.5218   5 2.0222 0.0822 48.0, 58.5 -0.39
LAT_HD m 62.15 0.91924   2   0.65 0.0148 61.5, 62.8 0.35
LAX_FC f 72.0 0.0   1   0.0 0.0 72.0, 72.0 1.09
LAX_FC m 72.1 0.0   1   0.0 0.0 72.1, 72.1 1.36
LEL_FH m 57.95 4.5962   2   3.25 0.0793 54.7, 61.2 -0.07
LIP_BG f 48.625 2.0759   4 1.0379 0.0427 45.6, 50.2 -0.95
LIP_BG m 45.6 0.0   1   0.0 0.0 45.6, 45.6 -1.33
LIV_DA f 48.3 0.0   1   0.0 0.0 48.3, 48.3 -0.98
LIV_DA m 53.75 2.6163   2   1.85 0.0487 51.9, 55.6 -0.5
LOD_AE f 55.53 0.60277   3 0.34801 0.0109 54.9, 56.1 -0.35
LOM_BG m 52.33 1.0017   3 0.57831 0.0191 51.2, 53.1 -0.64
LOT_FC f 57.78 2.1451   6 0.87575 0.0371 55.1, 60.4 -0.15
LOX_GF m 55.27 1.124   3 0.64893 0.0203 54.3, 56.5 -0.34
LUF_AD m 54.8 7.6867   5 3.4376 0.1403 45.8, 60.8 -0.39
LUG_EH m 68.5 0.88882   3 0.51316 0.013 67.8, 69.5 1.0
LUS_AH f 77.47 0.87369   3 0.50442 0.0113 76.5, 78.2 1.57
LUV_DG m 57.05 1.5843   4 0.79215 0.0278 55.6, 59.3 -0.16
LUZ_FH f 64.82 1.6761   4 0.83803 0.0259 62.7, 66.4 0.46
LUZ_FH m 63.8 0.0   1   0.0 0.0 63.8, 63.8 0.52
MERCURI_HF m 50.37 3.4675   3 2.0019 0.0688 46.5, 53.2 -0.84
NOD/ShiLtJ f 52.3 3.3941   2   2.4 0.0649 49.9, 54.7 -0.63
NOD/ShiLtJ m 55.5 0.56569   2   0.4 0.0102 55.1, 55.9 -0.32
NZO/HlLtJ f 64.7 4.3841   2   3.1 0.0678 61.6, 67.8 0.45
NZO/HlLtJ m 53.6 0.84853   2   0.6 0.0158 53.0, 54.2 -0.51
PAT_CD m 59.1 1.2767   3 0.73711 0.0216 57.7, 60.2 0.04
PEF_EC f 65.6 6.6091   3 3.8158 0.1007 58.0, 70.0 0.53
PEF_EC m 61.9 3.9051   3 2.2546 0.0631 59.4, 66.4 0.33
POH_DC f 59.73 2.5658   3 1.4814 0.043 56.9, 61.9 0.02
PWK/PhJ f 75.5 1.8385   2   1.3 0.0244 74.2, 76.8 1.4
PWK/PhJ m 71.6 1.9799   2   1.4 0.0277 70.2, 73.0 1.31
SEH_AH f 46.1 0.0   1   0.0 0.0 46.1, 46.1 -1.17
SEH_AH m 45.4 2.0461   4 1.0231 0.0451 42.6, 47.2 -1.35
STUCKY_HF f 68.7 3.2047   3 1.8502 0.0466 65.6, 72.0 0.8
STUCKY_HF m 69.3 0.0   1   0.0 0.0 69.3, 69.3 1.08
VIT_ED f 44.3 1.9519   3 1.1269 0.0441 42.4, 46.3 -1.32
VUX2_HF m 57.4 3.4771   3 2.0075 0.0606 53.7, 60.6 -0.13
WAD f 63.03 1.0599   3 0.61192 0.0168 61.9, 64.0 0.31
WSB/EiJ f 61.7 1.1314   2   0.8 0.0183 60.9, 62.5 0.19
WSB/EiJ m 62.25 1.7678   2   1.25 0.0284 61.0, 63.5 0.36
XAD8_BG f 44.0 0.0   1   0.0 0.0 44.0, 44.0 -1.35
XAD8_BG m 46.633 0.66583   3 0.38442 0.0143 45.9, 47.2 -1.22
XAH3_GH m 62.83 1.6166   3 0.93333 0.0257 61.9, 64.7 0.42
XAS4_AF m 56.37 0.37859   3 0.21858 0.0067 56.1, 56.8 -0.23
XAV_AH m 76.17 0.80829   3 0.46667 0.0106 75.3, 76.9 1.78
XAW2_CD m 65.55 2.8991   2   2.05 0.0442 63.5, 67.6 0.7
XEB2_AG f 75.77 1.5885   3 0.91712 0.021 74.8, 77.6 1.42
XEB2_AG m 74.93 0.49329   3 0.2848 0.0066 74.6, 75.5 1.65
XEB_AF f 71.2 0.98995   2   0.7 0.0139 70.5, 71.9 1.02
XEB_AF m 70.5 0.0   1   0.0 0.0 70.5, 70.5 1.2
XEQ_EH m 55.73 2.5541   3 1.4746 0.0458 53.7, 58.6 -0.3
XXEN2_DC m 66.17 1.097   3 0.63333 0.0166 64.9, 66.8 0.76
XXEN3_DC f 42.4 0.0   1   0.0 0.0 42.4, 42.4 -1.49
XXEN3_DC m 50.9 0.0   1   0.0 0.0 50.9, 50.9 -0.79
YOX_DE m 58.03 2.0841   3 1.2032 0.0359 56.2, 60.3 -0.06


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ 1 70.9 1.9114009793 74.7765008596 67.0234991404
129S1/SvImJ 2 67.5 1.4805648322 70.5027246542 64.4972753458
A/J 1 55.1 2.3409785466 59.8477245467 50.3522754533
A/J 2 55.0666666667 1.9114009793 58.9431675263 51.1901658071
BALB/cJ 1 54.98 1.4805648322 57.9827246542 51.9772753458
BALB/cJ 2 62.15 2.3409785466 66.8977245467 57.4022754533
BTBR T+ Itpr3tf/J 1 64.7 2.3409785466 69.4477245467 59.9522754533
BTBR T+ Itpr3tf/J 2 53.6 2.3409785466 58.3477245467 48.8522754533
C3H/HeJ 1 65.6 1.9114009793 69.4765008596 61.7234991404
C3H/HeJ 2 61.9 1.9114009793 65.7765008596 58.0234991404
C57BL/6J 1 75.7666666667 1.9114009793 79.6431675263 71.8901658071
C57BL/6J 2 74.9333333333 1.9114009793 78.8098341929 71.0568324737
CAST/EiJ 1 52.3 2.3409785466 57.0477245467 47.5522754533
CAST/EiJ 2 55.5 2.3409785466 60.2477245467 50.7522754533
DBA/2J 1 84.3 2.3409785466 89.0477245467 79.5522754533
DBA/2J 2 83.35 2.3409785466 88.0977245467 78.6022754533
FVB/NJ 1 75.5 2.3409785466 80.2477245467 70.7522754533
FVB/NJ 2 71.6 2.3409785466 76.3477245467 66.8522754533
LP/J 1 66.9 2.3409785466 71.6477245467 62.1522754533
LP/J 2 62.35 2.3409785466 67.0977245467 57.6022754533
NZB/BlNJ 1 65.05 2.3409785466 69.7977245467 60.3022754533
NZB/BlNJ 2 61.6 2.3409785466 66.3477245467 56.8522754533
SWR/J 1 61.7 2.3409785466 66.4477245467 56.9522754533
SWR/J 2 62.25 2.3409785466 66.9977245467 57.5022754533


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 69.2 1.2088761233 71.6517144136 66.7482855864
A/J both 55.0833333333 1.5110951541 58.1479763503 52.0186903163
BALB/cJ both 58.565 1.3849415852 61.3737917207 55.7562082793
BTBR T+ Itpr3tf/J both 59.15 1.6553218049 62.5071482222 55.7928517778
C3H/HeJ both 63.75 1.351564594 66.4911000451 61.0088999549
C57BL/6J both 75.35 1.351564594 78.0911000451 72.6088999549
CAST/EiJ both 53.9 1.6553218049 57.2571482222 50.5428517778
DBA/2J both 83.825 1.6553218049 87.1821482222 80.4678517778
FVB/NJ both 73.55 1.6553218049 76.9071482222 70.1928517778
LP/J both 64.625 1.6553218049 67.9821482222 61.2678517778
NZB/BlNJ both 63.325 1.6553218049 66.6821482222 59.9678517778
SWR/J both 61.975 1.6553218049 65.3321482222 58.6178517778




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA