Project measure / variable:   Graubert1   carcinoma_lung_enu

ID, description, units MPD:11657   carcinoma_lung_enu   lung carcinoma frequency rate   [score]  ENU  
ENU study
Data set, strains Graubert1   inbred   20 strains     sex: both     age: 13-68wks
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  STRAIN COMPARISON PLOT
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Graubert1 - lung carcinoma frequency rate ENU



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested20 strains20 strains
Mean of the strain means0.110   score 0.145   score
Median of the strain means0   score 0   score
SD of the strain means± 0.221 ± 0.213
Coefficient of variation (CV)2.01 1.47
Min–max range of strain means0   –   0.667   score 0   –   0.667   score
Mean sample size per strain6.1   mice 6.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0753 0.0753 0.9723 0.3253
strain 19 7.9487 0.4184 5.4043 < 0.0001
sex:strain 19 2.7439 0.1444 1.8656 0.0184
Residuals 200 15.4821 0.0774


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.0 0.0   6 0.0 0.0 -0.5
129S1/SvImJ m 0.167 0.408   6 0.167 2.45 0.1
A/J f 0.625 0.518   8 0.183 0.828 2.32
A/J m 0.667 0.516   6 0.211 0.775 2.46
AKR/J f 0.0 0.0   6 0.0 0.0 -0.5
AKR/J m 0.0 0.0   6 0.0 0.0 -0.68
BALB/cByJ f 0.0 0.0   6 0.0 0.0 -0.5
BALB/cByJ m 0.333 0.516   6 0.211 1.55 0.89
C3H/HeJ f 0.0 0.0   6 0.0 0.0 -0.5
C3H/HeJ m 0.0 0.0   6 0.0 0.0 -0.68
C57BL/6J f 0.0 0.0   6 0.0 0.0 -0.5
C57BL/6J m 0.0 0.0   7 0.0 0.0 -0.68
C57L/J f 0.0 0.0   6 0.0 0.0 -0.5
C57L/J m 0.0 0.0   6 0.0 0.0 -0.68
C58/J f 0.0 0.0   6 0.0 0.0 -0.5
C58/J m 0.0 0.0   6 0.0 0.0 -0.68
CAST/EiJ f 0.0 0.0   6 0.0 0.0 -0.5
CAST/EiJ m 0.0 0.0   6 0.0 0.0 -0.68
DBA/2J f 0.0 0.0   5 0.0 0.0 -0.5
DBA/2J m 0.143 0.378   7 0.143 2.65 -0.01
FVB/NJ f 0.0 0.0   6 0.0 0.0 -0.5
FVB/NJ m 0.667 0.516   6 0.211 0.775 2.46
MOLF/EiJ f 0.5 0.707   2   0.5 1.41 1.76
MOLF/EiJ m 0.0 0.0   5 0.0 0.0 -0.68
NOD/ShiLtJ f 0.0 0.0   6 0.0 0.0 -0.5
NOD/ShiLtJ m 0.167 0.408   6 0.167 2.45 0.1
NZB/BlNJ f 0.0 0.0   6 0.0 0.0 -0.5
NZB/BlNJ m 0.0 0.0   6 0.0 0.0 -0.68
PERA/EiJ f 0.667 0.516   6 0.211 0.775 2.51
PERA/EiJ m 0.333 0.516   6 0.211 1.55 0.89
PL/J f 0.167 0.408   6 0.167 2.45 0.26
PL/J m 0.0 0.0   6 0.0 0.0 -0.68
SJL/J f 0.0 0.0   4 0.0 0.0 -0.5
SJL/J m 0.0 0.0   6 0.0 0.0 -0.68
SM/J f 0.0 0.0   6 0.0 0.0 -0.5
SM/J m 0.0 0.0   6 0.0 0.0 -0.68
SPRET/EiJ f 0.0 0.0   10 0.0 0.0 -0.5
SPRET/EiJ m 0.25 0.5   4 0.25 2.0 0.5
SWR/J f 0.25 0.463   8 0.164 1.85 0.63
SWR/J m 0.167 0.408   6 0.167 2.45 0.1


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.0 0.1136 0.224 -0.224
129S1/SvImJ m 0.1667 0.1136 0.3906 -0.0573
A/J f 0.625 0.0984 0.819 0.431
A/J m 0.6667 0.1136 0.8906 0.4427
AKR/J f 0.0 0.1136 0.224 -0.224
AKR/J m 0.0 0.1136 0.224 -0.224
BALB/cByJ f 0.0 0.1136 0.224 -0.224
BALB/cByJ m 0.3333 0.1136 0.5573 0.1094
C3H/HeJ f 0.0 0.1136 0.224 -0.224
C3H/HeJ m 0.0 0.1136 0.224 -0.224
C57BL/6J f 0.0 0.1136 0.224 -0.224
C57BL/6J m 0.0 0.1052 0.2074 -0.2074
C57L/J f 0.0 0.1136 0.224 -0.224
C57L/J m 0.0 0.1136 0.224 -0.224
C58/J f 0.0 0.1136 0.224 -0.224
C58/J m 0.0 0.1136 0.224 -0.224
CAST/EiJ f 0.0 0.1136 0.224 -0.224
CAST/EiJ m 0.0 0.1136 0.224 -0.224
DBA/2J f 0.0 0.1244 0.2454 -0.2454
DBA/2J m 0.1429 0.1052 0.3502 -0.0645
FVB/NJ f 0.0 0.1136 0.224 -0.224
FVB/NJ m 0.6667 0.1136 0.8906 0.4427
MOLF/EiJ f 0.5 0.1967 0.8879 0.1121
MOLF/EiJ m 0.0 0.1244 0.2454 -0.2454
NOD/ShiLtJ f 0.0 0.1136 0.224 -0.224
NOD/ShiLtJ m 0.1667 0.1136 0.3906 -0.0573
NZB/BlNJ f 0.0 0.1136 0.224 -0.224
NZB/BlNJ m 0.0 0.1136 0.224 -0.224
PERA/EiJ f 0.6667 0.1136 0.8906 0.4427
PERA/EiJ m 0.3333 0.1136 0.5573 0.1094
PL/J f 0.1667 0.1136 0.3906 -0.0573
PL/J m 0.0 0.1136 0.224 -0.224
SJL/J f 0.0 0.1391 0.2743 -0.2743
SJL/J m 0.0 0.1136 0.224 -0.224
SM/J f 0.0 0.1136 0.224 -0.224
SM/J m 0.0 0.1136 0.224 -0.224
SPRET/EiJ f 0.0 0.088 0.1735 -0.1735
SPRET/EiJ m 0.25 0.1391 0.5243 -0.0243
SWR/J f 0.25 0.0984 0.444 0.056
SWR/J m 0.1667 0.1136 0.3906 -0.0573


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.0833 0.0803 0.2417 -0.075
A/J both 0.6458 0.0751 0.794 0.4977
AKR/J both 0.0 0.0803 0.1584 -0.1584
BALB/cByJ both 0.1667 0.0803 0.325 0.0083
C3H/HeJ both 0.0 0.0803 0.1584 -0.1584
C57BL/6J both 0.0 0.0774 0.1526 -0.1526
C57L/J both 0.0 0.0803 0.1584 -0.1584
C58/J both 0.0 0.0803 0.1584 -0.1584
CAST/EiJ both 0.0 0.0803 0.1584 -0.1584
DBA/2J both 0.0714 0.0815 0.2321 -0.0892
FVB/NJ both 0.3333 0.0803 0.4917 0.175
MOLF/EiJ both 0.25 0.1164 0.4795 0.0205
NOD/ShiLtJ both 0.0833 0.0803 0.2417 -0.075
NZB/BlNJ both 0.0 0.0803 0.1584 -0.1584
PERA/EiJ both 0.5 0.0803 0.6584 0.3416
PL/J both 0.0833 0.0803 0.2417 -0.075
SJL/J both 0.0 0.0898 0.1771 -0.1771
SM/J both 0.0 0.0803 0.1584 -0.1584
SPRET/EiJ both 0.125 0.0823 0.2873 -0.0373
SWR/J both 0.2083 0.0751 0.3565 0.0602




  GWAS USING LINEAR MIXED MODELS