Phenotype measure:   Graubert1   adenoma_lung_enu


  STRAIN COMPARISON PLOT
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Graubert1 - lung adenoma frequency rate ENU



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested20 strains20 strains
Mean of the strain means0.00835   score 0.102   score
Median of the strain means0   score 0   score
SD of the strain means± 0.0373 ± 0.138
Coefficient of variation (CV)4.47 1.36
Min–max range of strain means0   –   0.167   score 0   –   0.500   score
Mean sample size per strain6.1   mice 6.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.5142 0.5142 10.863 0.0012
strain 19 1.2335 0.0649 1.3716 0.1442
sex:strain 19 1.0815 0.0569 1.2025 0.2583
Residuals 200 9.4667 0.0473


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.0 0.0   6 0.0 0.0 -0.22
129S1/SvImJ m 0.5 0.548   6 0.224 1.1 2.89
A/J f 0.0 0.0   8 0.0 0.0 -0.22
A/J m 0.167 0.408   6 0.167 2.45 0.47
AKR/J f 0.0 0.0   6 0.0 0.0 -0.22
AKR/J m 0.0 0.0   6 0.0 0.0 -0.74
BALB/cByJ f 0.0 0.0   6 0.0 0.0 -0.22
BALB/cByJ m 0.0 0.0   6 0.0 0.0 -0.74
C3H/HeJ f 0.0 0.0   6 0.0 0.0 -0.22
C3H/HeJ m 0.333 0.516   6 0.211 1.55 1.68
C57BL/6J f 0.0 0.0   6 0.0 0.0 -0.22
C57BL/6J m 0.0 0.0   7 0.0 0.0 -0.74
C57L/J f 0.0 0.0   6 0.0 0.0 -0.22
C57L/J m 0.0 0.0   6 0.0 0.0 -0.74
C58/J f 0.0 0.0   6 0.0 0.0 -0.22
C58/J m 0.0 0.0   6 0.0 0.0 -0.74
CAST/EiJ f 0.0 0.0   6 0.0 0.0 -0.22
CAST/EiJ m 0.0 0.0   6 0.0 0.0 -0.74
DBA/2J f 0.0 0.0   5 0.0 0.0 -0.22
DBA/2J m 0.0 0.0   7 0.0 0.0 -0.74
FVB/NJ f 0.0 0.0   6 0.0 0.0 -0.22
FVB/NJ m 0.0 0.0   6 0.0 0.0 -0.74
MOLF/EiJ f 0.0 0.0   2   0.0 0.0 -0.22
MOLF/EiJ m 0.2 0.447   5 0.2 2.24 0.71
NOD/ShiLtJ f 0.0 0.0   6 0.0 0.0 -0.22
NOD/ShiLtJ m 0.167 0.408   6 0.167 2.45 0.47
NZB/BlNJ f 0.0 0.0   6 0.0 0.0 -0.22
NZB/BlNJ m 0.167 0.408   6 0.167 2.45 0.47
PERA/EiJ f 0.0 0.0   6 0.0 0.0 -0.22
PERA/EiJ m 0.167 0.408   6 0.167 2.45 0.47
PL/J f 0.0 0.0   6 0.0 0.0 -0.22
PL/J m 0.0 0.0   6 0.0 0.0 -0.74
SJL/J f 0.0 0.0   4 0.0 0.0 -0.22
SJL/J m 0.167 0.408   6 0.167 2.45 0.47
SM/J f 0.167 0.408   6 0.167 2.45 4.25
SM/J m 0.167 0.408   6 0.167 2.45 0.47
SPRET/EiJ f 0.0 0.0   10 0.0 0.0 -0.22
SPRET/EiJ m 0.0 0.0   4 0.0 0.0 -0.74
SWR/J f 0.0 0.0   8 0.0 0.0 -0.22
SWR/J m 0.0 0.0   6 0.0 0.0 -0.74


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.0 0.0888 0.1751 -0.1751
129S1/SvImJ m 0.5 0.0888 0.6751 0.3249
A/J f 0.0 0.0769 0.1517 -0.1517
A/J m 0.1667 0.0888 0.3418 -0.0085
AKR/J f 0.0 0.0888 0.1751 -0.1751
AKR/J m 0.0 0.0888 0.1751 -0.1751
BALB/cByJ f 0.0 0.0888 0.1751 -0.1751
BALB/cByJ m 0.0 0.0888 0.1751 -0.1751
C3H/HeJ f 0.0 0.0888 0.1751 -0.1751
C3H/HeJ m 0.3333 0.0888 0.5085 0.1582
C57BL/6J f 0.0 0.0888 0.1751 -0.1751
C57BL/6J m 0.0 0.0822 0.1622 -0.1622
C57L/J f 0.0 0.0888 0.1751 -0.1751
C57L/J m 0.0 0.0888 0.1751 -0.1751
C58/J f 0.0 0.0888 0.1751 -0.1751
C58/J m 0.0 0.0888 0.1751 -0.1751
CAST/EiJ f 0.0 0.0888 0.1751 -0.1751
CAST/EiJ m 0.0 0.0888 0.1751 -0.1751
DBA/2J f 0.0 0.0973 0.1919 -0.1919
DBA/2J m 0.0 0.0822 0.1622 -0.1622
FVB/NJ f 0.0 0.0888 0.1751 -0.1751
FVB/NJ m 0.0 0.0888 0.1751 -0.1751
MOLF/EiJ f 0.0 0.1538 0.3034 -0.3034
MOLF/EiJ m 0.2 0.0973 0.3919 0.0081
NOD/ShiLtJ f 0.0 0.0888 0.1751 -0.1751
NOD/ShiLtJ m 0.1667 0.0888 0.3418 -0.0085
NZB/BlNJ f 0.0 0.0888 0.1751 -0.1751
NZB/BlNJ m 0.1667 0.0888 0.3418 -0.0085
PERA/EiJ f 0.0 0.0888 0.1751 -0.1751
PERA/EiJ m 0.1667 0.0888 0.3418 -0.0085
PL/J f 0.0 0.0888 0.1751 -0.1751
PL/J m 0.0 0.0888 0.1751 -0.1751
SJL/J f 0.0 0.1088 0.2145 -0.2145
SJL/J m 0.1667 0.0888 0.3418 -0.0085
SM/J f 0.1667 0.0888 0.3418 -0.0085
SM/J m 0.1667 0.0888 0.3418 -0.0085
SPRET/EiJ f 0.0 0.0688 0.1357 -0.1357
SPRET/EiJ m 0.0 0.1088 0.2145 -0.2145
SWR/J f 0.0 0.0769 0.1517 -0.1517
SWR/J m 0.0 0.0888 0.1751 -0.1751


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.25 0.0628 0.3738 0.1262
A/J both 0.0833 0.0587 0.1992 -0.0325
AKR/J both 0.0 0.0628 0.1238 -0.1238
BALB/cByJ both 0.0 0.0628 0.1238 -0.1238
C3H/HeJ both 0.1667 0.0628 0.2905 0.0428
C57BL/6J both 0.0 0.0605 0.1193 -0.1193
C57L/J both 0.0 0.0628 0.1238 -0.1238
C58/J both 0.0 0.0628 0.1238 -0.1238
CAST/EiJ both 0.0 0.0628 0.1238 -0.1238
DBA/2J both 0.0 0.0637 0.1256 -0.1256
FVB/NJ both 0.0 0.0628 0.1238 -0.1238
MOLF/EiJ both 0.1 0.091 0.2795 -0.0795
NOD/ShiLtJ both 0.0833 0.0628 0.2072 -0.0405
NZB/BlNJ both 0.0833 0.0628 0.2072 -0.0405
PERA/EiJ both 0.0833 0.0628 0.2072 -0.0405
PL/J both 0.0 0.0628 0.1238 -0.1238
SJL/J both 0.0833 0.0702 0.2218 -0.0551
SM/J both 0.1667 0.0628 0.2905 0.0428
SPRET/EiJ both 0.0 0.0644 0.1269 -0.1269
SWR/J both 0.0 0.0587 0.1158 -0.1158




  GWAS USING LINEAR MIXED MODELS