Project measure / variable:   Graubert1   LYMP

ID, description, units MPD:11603   LYMP   lymphocyte count (LYMP; units per volume x 103)   [n/µL]  
Data set, strains Graubert1   inbred   20 strains     sex: both     age: 9wks
Procedure complete blood count
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  STRAIN COMPARISON PLOT
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Graubert1 - lymphocyte count (LYMP; units per volume x 103)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested20 strains20 strains
Mean of the strain means5.07   n/µL 5.69   n/µL
Median of the strain means5.22   n/µL 5.60   n/µL
SD of the strain means± 1.71 ± 1.68
Coefficient of variation (CV)0.338 0.296
Min–max range of strain means1.92   –   8.83   n/µL 2.31   –   9.47   n/µL
Mean sample size per strain11.9   mice 11.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 52.9511 52.9511 18.6942 < 0.0001
strain 19 1156.8449 60.8866 21.4958 < 0.0001
sex:strain 19 143.1313 7.5332 2.6596 0.0002
Residuals 422 1195.3116 2.8325


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 4.7 1.31   12 0.379 0.279 2.09, 6.63 -0.22
129S1/SvImJ m 6.51 1.03   12 0.296 0.158 4.79, 7.96 0.49
A/J f 4.03 1.31   12 0.379 0.325 2.23, 6.11 -0.61
A/J m 4.33 1.25   12 0.362 0.289 2.83, 6.77 -0.81
AKR/J f 6.27 1.78   12 0.513 0.283 3.4, 8.62 0.7
AKR/J m 5.66 0.818   12 0.236 0.145 4.31, 7.07 -0.02
BALB/cByJ f 6.33 1.23   12 0.354 0.194 4.62, 8.59 0.74
BALB/cByJ m 7.16 0.933   12 0.269 0.13 5.3, 8.76 0.87
C3H/HeJ f 3.6 1.29   12 0.374 0.359 2.15, 6.33 -0.86
C3H/HeJ m 5.03 1.73   12 0.5 0.344 2.43, 8.04 -0.39
C57BL/6J f 6.56 1.88   12 0.541 0.286 4.31, 10.3 0.87
C57BL/6J m 4.89 1.67   13 0.462 0.341 2.36, 8.51 -0.47
C57L/J f 5.0 1.2   12 0.348 0.241 2.25, 6.81 -0.04
C57L/J m 5.7 1.57   12 0.452 0.275 4.32, 9.99 0.01
C58/J f 5.44 0.861   12 0.249 0.158 3.54, 6.47 0.22
C58/J m 7.2 2.25   12 0.648 0.312 4.52, 13.2 0.9
CAST/EiJ f 3.96 1.81   12 0.524 0.458 0.96, 6.06 -0.65
CAST/EiJ m 4.88 1.89   12 0.546 0.388 1.81, 8.42 -0.48
DBA/2J f 4.42 1.4   11 0.423 0.317 2.84, 7.03 -0.38
DBA/2J m 5.44 2.34   9 0.779 0.43 2.44, 9.33 -0.15
FVB/NJ f 5.62 1.56   11 0.472 0.279 3.75, 8.17 0.32
FVB/NJ m 5.54 1.4   12 0.404 0.253 3.97, 8.62 -0.09
MOLF/EiJ f 5.47 1.84   3 1.06 0.337 3.68, 7.36 0.23
MOLF/EiJ m 5.99 2.12   11 0.64 0.354 3.28, 10.0 0.18
NOD/ShiLtJ f 3.53 1.32   12 0.382 0.375 0.95, 6.39 -0.9
NOD/ShiLtJ m 4.31 0.865   12 0.25 0.201 2.15, 5.17 -0.82
NZB/BlNJ f 1.92 0.675   12 0.195 0.352 1.23, 3.4 -1.84
NZB/BlNJ m 2.31 1.12   12 0.325 0.487 1.26, 5.44 -2.01
PERA/EiJ f 7.24 1.62   12 0.468 0.224 4.34, 9.64 1.27
PERA/EiJ m 7.31 1.46   12 0.422 0.2 5.29, 9.98 0.96
PL/J f 6.85 2.24   12 0.646 0.327 2.6, 12.3 1.04
PL/J m 6.97 1.67   12 0.483 0.24 4.14, 10.4 0.76
SJL/J f 5.82 2.3   12 0.663 0.395 2.94, 9.81 0.44
SJL/J m 9.47 2.2   12 0.636 0.233 6.7, 13.3 2.25
SM/J f 2.4 1.03   12 0.298 0.429 0.98, 4.22 -1.56
SM/J m 3.31 0.722   12 0.208 0.218 2.2, 4.57 -1.41
SPRET/EiJ f 3.4 1.2   13 0.332 0.352 0.91, 6.16 -0.98
SPRET/EiJ m 3.95 1.17   7 0.443 0.296 2.52, 5.13 -1.03
SWR/J f 8.83 2.98   12 0.86 0.337 3.49, 12.4 2.2
SWR/J m 7.79 3.78   12 1.09 0.485 3.05, 13.0 1.25


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 4.7042 0.4858 5.6591 3.7492
129S1/SvImJ m 6.5133 0.4858 7.4683 5.5584
A/J f 4.0325 0.4858 4.9875 3.0775
A/J m 4.33 0.4858 5.285 3.375
AKR/J f 6.2683 0.4858 7.2233 5.3134
AKR/J m 5.6592 0.4858 6.6141 4.7042
BALB/cByJ f 6.3292 0.4858 7.2841 5.3742
BALB/cByJ m 7.1625 0.4858 8.1175 6.2075
C3H/HeJ f 3.6017 0.4858 4.5566 2.6467
C3H/HeJ m 5.0317 0.4858 5.9866 4.0767
C57BL/6J f 6.5567 0.4858 7.5116 5.6017
C57BL/6J m 4.8885 0.4668 5.806 3.971
C57L/J f 5.0042 0.4858 5.9591 4.0492
C57L/J m 5.7017 0.4858 6.6566 4.7467
C58/J f 5.4392 0.4858 6.3941 4.4842
C58/J m 7.2033 0.4858 8.1583 6.2484
CAST/EiJ f 3.9625 0.4858 4.9175 3.0075
CAST/EiJ m 4.8783 0.4858 5.8333 3.9234
DBA/2J f 4.4191 0.5074 5.4165 3.4217
DBA/2J m 5.44 0.561 6.5427 4.3373
FVB/NJ f 5.6155 0.5074 6.6129 4.618
FVB/NJ m 5.5392 0.4858 6.4941 4.5842
MOLF/EiJ f 5.4667 0.9717 7.3766 3.5567
MOLF/EiJ m 5.9927 0.5074 6.9902 4.9953
NOD/ShiLtJ f 3.5283 0.4858 4.4833 2.5734
NOD/ShiLtJ m 4.31 0.4858 5.265 3.355
NZB/BlNJ f 1.9175 0.4858 2.8725 0.9625
NZB/BlNJ m 2.3083 0.4858 3.2633 1.3534
PERA/EiJ f 7.2425 0.4858 8.1975 6.2875
PERA/EiJ m 7.3125 0.4858 8.2675 6.3575
PL/J f 6.8475 0.4858 7.8025 5.8925
PL/J m 6.97 0.4858 7.925 6.015
SJL/J f 5.8192 0.4858 6.7741 4.8642
SJL/J m 9.4733 0.4858 10.4283 8.5184
SM/J f 2.4033 0.4858 3.3583 1.4484
SM/J m 3.3075 0.4858 4.2625 2.3525
SPRET/EiJ f 3.3985 0.4668 4.316 2.481
SPRET/EiJ m 3.9529 0.6361 5.2032 2.7025
SWR/J f 8.8275 0.4858 9.7825 7.8725
SWR/J m 7.7867 0.4858 8.7416 6.8317


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 5.6088 0.3435 6.284 4.9335
A/J both 4.1812 0.3435 4.8565 3.506
AKR/J both 5.9637 0.3435 6.639 5.2885
BALB/cByJ both 6.7458 0.3435 7.4211 6.0706
C3H/HeJ both 4.3167 0.3435 4.9919 3.6414
C57BL/6J both 5.7226 0.3369 6.3847 5.0604
C57L/J both 5.3529 0.3435 6.0282 4.6777
C58/J both 6.3213 0.3435 6.9965 5.646
CAST/EiJ both 4.4204 0.3435 5.0957 3.7452
DBA/2J both 4.9295 0.3782 5.673 4.1861
FVB/NJ both 5.5773 0.3513 6.2678 4.8869
MOLF/EiJ both 5.7297 0.5481 6.807 4.6523
NOD/ShiLtJ both 3.9192 0.3435 4.5944 3.2439
NZB/BlNJ both 2.1129 0.3435 2.7882 1.4377
PERA/EiJ both 7.2775 0.3435 7.9528 6.6022
PL/J both 6.9087 0.3435 7.584 6.2335
SJL/J both 7.6463 0.3435 8.3215 6.971
SM/J both 2.8554 0.3435 3.5307 2.1802
SPRET/EiJ both 3.6757 0.3945 4.4511 2.9002
SWR/J both 8.3071 0.3435 8.9823 7.6318




  GWAS USING LINEAR MIXED MODELS