Phenotype measure:   Donahue1   skull_width

ID, description, units MPD:11521   skull_width   skull width   [mm]
Data set, strains Donahue1   inbred w/CC7   29 strains     sex: both     age: 15-16wks
Procedure DXA
Ontology mappings

  STRAIN COMPARISON PLOT
Dimensions Width:   px    Height:   px
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Donahue1 - skull width



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains29 strains
Mean of the strain means9.92   mm 10.0   mm
Median of the strain means10.1   mm 10.2   mm
SD of the strain means± 0.624 ± 0.640
Coefficient of variation (CV)0.0629 0.0639
Min–max range of strain means8.70   –   10.7   mm 8.85   –   10.8   mm
Mean sample size per strain9.5   mice 9.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1.0789 1.0789 35.0664 < 0.0001
strain 28 200.8162 7.172 233.0942 < 0.0001
sex:strain 28 2.3674 0.0845 2.7479 < 0.0001
Residuals 485 14.9228 0.0308


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 10.7 0.151   10 0.0476 0.014 10.5, 11.0 1.26
129S1/SvImJ m 10.8 0.127   10 0.0401 0.0117 10.6, 11.0 1.24
A/J f 10.1 0.172   10 0.0544 0.017 9.89, 10.4 0.3
A/J m 10.2 0.136   8 0.0483 0.0134 9.96, 10.4 0.3
AKR/J f 10.6 0.177   10 0.0559 0.0166 10.3, 10.9 1.1
AKR/J m 10.7 0.0707   9 0.0236 0.00663 10.6, 10.8 1.08
BALB/cJ f 10.2 0.0943   10 0.0298 0.00924 10.0, 10.3 0.46
BALB/cJ m 10.7 0.125   10 0.0394 0.0117 10.5, 10.9 1.08
BTBR T+ Itpr3tf/J f 10.7 0.181   9 0.0603 0.017 10.3, 10.9 1.26
BTBR T+ Itpr3tf/J m 10.7 0.105   10 0.0333 0.00985 10.6, 10.9 1.08
BUB/BnJ f 10.5 0.2   9 0.0667 0.019 10.2, 10.8 0.94
BUB/BnJ m 10.2 0.0756   8 0.0267 0.00737 10.2, 10.4 0.3
C3H/HeJ f 10.5 0.233   10 0.0737 0.0222 10.1, 10.9 0.94
C3H/HeJ m 10.7 0.201   10 0.0636 0.0189 10.3, 10.9 1.08
C57BL/6J f 10.5 0.189   10 0.0597 0.018 10.1, 10.7 0.94
C57BL/6J m 10.7 0.195   10 0.0616 0.0182 10.4, 11.0 1.08
C57L/J f 10.4 0.195   10 0.0616 0.0188 10.1, 10.6 0.78
C57L/J m 10.5 0.197   10 0.0623 0.0187 10.2, 10.9 0.77
C58/J f 9.85 0.208   10 0.0656 0.0211 9.37, 10.2 -0.11
C58/J m 9.86 0.271   8 0.0958 0.0275 9.6, 10.4 -0.23
CAST/EiJ f 9.0 0.261   9 0.0871 0.029 8.4, 9.3 -1.47
CAST/EiJ m 9.1 0.233   9 0.0778 0.0257 8.8, 9.42 -1.42
CZECHII/EiJ f 8.99 0.129   8 0.0455 0.0143 8.87, 9.21 -1.48
CZECHII/EiJ m 8.94 0.223   9 0.0745 0.025 8.47, 9.2 -1.67
DBA/2J f 9.86 0.16   10 0.0506 0.0162 9.63, 10.2 -0.09
DBA/2J m 9.73 0.145   9 0.0482 0.0149 9.47, 9.94 -0.44
FVB/NJ f 10.0 0.189   10 0.0599 0.0189 9.8, 10.4 0.13
FVB/NJ m 10.2 0.14   10 0.0441 0.0137 9.92, 10.3 0.3
JF1/MsJ f 9.29 0.156   9 0.0519 0.0168 9.09, 9.62 -1.0
JF1/MsJ m 9.21 0.124   9 0.0413 0.0134 9.03, 9.38 -1.25
MOLF/EiJ f 8.7 0.152   10 0.0479 0.0174 8.52, 8.95 -1.95
MOLF/EiJ m 8.89 0.15   7 0.0569 0.0169 8.58, 9.03 -1.75
MSM/MsJ f 8.99 0.0807   8 0.0285 0.00898 8.88, 9.15 -1.48
MSM/MsJ m 9.0 0.202   7 0.0762 0.0224 8.68, 9.28 -1.58
NOD/ShiLtJ f 10.6 0.166   10 0.0526 0.0157 10.4, 10.9 1.1
NOD/ShiLtJ m 10.7 0.196   10 0.0618 0.0182 10.4, 11.0 1.08
NZB/BlNJ f 10.4 0.106   10 0.0335 0.0102 10.3, 10.6 0.78
NZB/BlNJ m 10.6 0.328   10 0.104 0.031 10.2, 11.2 0.92
NZW/LacJ f 10.5 0.148   10 0.0467 0.014 10.3, 10.8 0.94
NZW/LacJ m 10.5 0.19   10 0.06 0.018 10.2, 10.8 0.77
PERA/EiJ f 9.89 0.13   8 0.0459 0.0131 9.67, 10.1 -0.04
PERA/EiJ m 9.93 0.166   10 0.0524 0.0167 9.7, 10.2 -0.12
PL/J f 10.1 0.167   10 0.0527 0.0165 9.88, 10.4 0.3
PL/J m 10.2 0.121   9 0.0404 0.0119 9.98, 10.3 0.3
PWK/PhJ f 9.33 0.243   7 0.0919 0.0261 8.87, 9.58 -0.94
PWK/PhJ m 9.53 0.182   9 0.0607 0.0191 9.32, 9.87 -0.75
SEA/GnJ f 10.2 0.195   11 0.0588 0.0191 9.9, 10.5 0.46
SEA/GnJ m 10.3 0.157   10 0.0496 0.0152 10.1, 10.6 0.45
SJL/J f 9.52 0.0764   10 0.0241 0.00802 9.4, 9.67 -0.63
SJL/J m 9.6 0.205   10 0.0647 0.0213 9.2, 9.81 -0.64
SM/J f 9.77 0.157   9 0.0523 0.0161 9.52, 10.0 -0.23
SM/J m 9.92 0.189   10 0.0599 0.0191 9.56, 10.2 -0.14
SPRET/EiJ f 8.73 0.329   7 0.124 0.0377 8.27, 9.35 -1.9
SPRET/EiJ m 8.85 0.151   10 0.0477 0.0171 8.57, 9.12 -1.81
SWR/J f 10.2 0.0823   10 0.026 0.00805 10.1, 10.3 0.46
SWR/J m 10.3 0.132   10 0.0416 0.0128 10.2, 10.6 0.45
WSB/EiJ f 9.44 0.133   10 0.042 0.0141 9.26, 9.67 -0.76
WSB/EiJ m 9.71 0.147   8 0.0521 0.0152 9.43, 9.89 -0.47


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 10.74 0.0555 10.849 10.631
129S1/SvImJ m 10.85 0.0555 10.959 10.741
A/J f 10.104 0.0555 10.213 9.995
A/J m 10.17 0.062 10.2919 10.0481
AKR/J f 10.63 0.0555 10.739 10.521
AKR/J m 10.6667 0.0585 10.7816 10.5518
BALB/cJ f 10.2 0.0555 10.309 10.091
BALB/cJ m 10.7 0.0555 10.809 10.591
BTBR T+ Itpr3tf/J f 10.6556 0.0585 10.7704 10.5407
BTBR T+ Itpr3tf/J m 10.7 0.0555 10.809 10.591
BUB/BnJ f 10.5333 0.0585 10.6482 10.4184
BUB/BnJ m 10.25 0.062 10.3719 10.1281
C3H/HeJ f 10.51 0.0555 10.619 10.401
C3H/HeJ m 10.66 0.0555 10.769 10.551
C57BL/6J f 10.47 0.0555 10.579 10.361
C57BL/6J m 10.67 0.0555 10.779 10.561
C57L/J f 10.37 0.0555 10.479 10.261
C57L/J m 10.51 0.0555 10.619 10.401
C58/J f 9.848 0.0555 9.957 9.739
C58/J m 9.8587 0.062 9.9806 9.7369
CAST/EiJ f 9.0044 0.0585 9.1193 8.8896
CAST/EiJ m 9.0989 0.0585 9.2138 8.984
CZECHII/EiJ f 8.995 0.062 9.1169 8.8731
CZECHII/EiJ m 8.9411 0.0585 9.056 8.8262
DBA/2J f 9.859 0.0555 9.968 9.75
DBA/2J m 9.7322 0.0585 9.8471 9.6173
FVB/NJ f 10.018 0.0555 10.127 9.909
FVB/NJ m 10.152 0.0555 10.261 10.043
JF1/MsJ f 9.2878 0.0585 9.4027 9.1729
JF1/MsJ m 9.2089 0.0585 9.3238 9.094
MOLF/EiJ f 8.703 0.0555 8.812 8.594
MOLF/EiJ m 8.8943 0.0663 9.0246 8.764
MSM/MsJ f 8.9875 0.062 9.1094 8.8656
MSM/MsJ m 9.0 0.0663 9.1303 8.8697
NOD/ShiLtJ f 10.61 0.0555 10.719 10.501
NOD/ShiLtJ m 10.74 0.0555 10.849 10.631
NZB/BlNJ f 10.43 0.0555 10.539 10.321
NZB/BlNJ m 10.59 0.0555 10.699 10.481
NZW/LacJ f 10.52 0.0555 10.629 10.411
NZW/LacJ m 10.54 0.0555 10.649 10.431
PERA/EiJ f 9.89 0.062 10.0119 9.7681
PERA/EiJ m 9.932 0.0555 10.041 9.823
PL/J f 10.117 0.0555 10.226 10.008
PL/J m 10.2089 0.0585 10.3238 10.094
PWK/PhJ f 9.3314 0.0663 9.4617 9.2012
PWK/PhJ m 9.5278 0.0585 9.6427 9.4129
SEA/GnJ f 10.2 0.0529 10.3039 10.0961
SEA/GnJ m 10.33 0.0555 10.439 10.221
SJL/J f 9.519 0.0555 9.628 9.41
SJL/J m 9.605 0.0555 9.714 9.496
SM/J f 9.7744 0.0585 9.8893 9.6596
SM/J m 9.92 0.0555 10.029 9.811
SPRET/EiJ f 8.7257 0.0663 8.856 8.5954
SPRET/EiJ m 8.847 0.0555 8.956 8.738
SWR/J f 10.23 0.0555 10.339 10.121
SWR/J m 10.32 0.0555 10.429 10.211
WSB/EiJ f 9.444 0.0555 9.553 9.335
WSB/EiJ m 9.7113 0.062 9.8331 9.5894


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 10.795 0.0392 10.8721 10.7179
A/J both 10.137 0.0416 10.2187 10.0553
AKR/J both 10.6483 0.0403 10.7275 10.5692
BALB/cJ both 10.45 0.0392 10.5271 10.3729
BTBR T+ Itpr3tf/J both 10.6778 0.0403 10.757 10.5986
BUB/BnJ both 10.3917 0.0426 10.4754 10.3079
C3H/HeJ both 10.585 0.0392 10.6621 10.5079
C57BL/6J both 10.57 0.0392 10.6471 10.4929
C57L/J both 10.44 0.0392 10.5171 10.3629
C58/J both 9.8534 0.0416 9.9351 9.7716
CAST/EiJ both 9.0517 0.0413 9.1329 8.9704
CZECHII/EiJ both 8.9681 0.0426 9.0518 8.8843
DBA/2J both 9.7956 0.0403 9.8748 9.7164
FVB/NJ both 10.085 0.0392 10.1621 10.0079
JF1/MsJ both 9.2483 0.0413 9.3296 9.1671
MOLF/EiJ both 8.7986 0.0432 8.8836 8.7137
MSM/MsJ both 8.9937 0.0454 9.0829 8.9046
NOD/ShiLtJ both 10.675 0.0392 10.7521 10.5979
NZB/BlNJ both 10.51 0.0392 10.5871 10.4329
NZW/LacJ both 10.53 0.0392 10.6071 10.4529
PERA/EiJ both 9.911 0.0416 9.9927 9.8293
PL/J both 10.1629 0.0403 10.2421 10.0838
PWK/PhJ both 9.4296 0.0442 9.5164 9.3428
SEA/GnJ both 10.265 0.0383 10.3403 10.1897
SJL/J both 9.562 0.0392 9.6391 9.4849
SM/J both 9.8472 0.0403 9.9264 9.768
SPRET/EiJ both 8.7864 0.0432 8.8713 8.7014
SWR/J both 10.275 0.0392 10.3521 10.1979
WSB/EiJ both 9.5776 0.0416 9.6594 9.4959




  GWAS USING LINEAR MIXED MODELS