Phenotype measure:   Donahue1   skull_height

ID, description, units MPD:11520   skull_height   skull height   [mm]
Data set, strains Donahue1   inbred w/CC7   29 strains     sex: both     age: 15-16wks
Procedure DXA
Ontology mappings

  STRAIN COMPARISON PLOT
Dimensions Width:   px    Height:   px
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Donahue1 - skull height



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains29 strains
Mean of the strain means9.88   mm 9.98   mm
Median of the strain means10.1   mm 10.1   mm
SD of the strain means± 0.575 ± 0.629
Coefficient of variation (CV)0.0582 0.0630
Min–max range of strain means8.73   –   10.8   mm 8.66   –   11.2   mm
Mean sample size per strain9.5   mice 9.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1.6552 1.6552 25.5664 < 0.0001
strain 28 179.3763 6.4063 98.9518 < 0.0001
sex:strain 28 3.6793 0.1314 2.0296 0.0016
Residuals 485 31.3996 0.0647


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 10.2 0.291   10 0.0921 0.0287 9.6, 10.6 0.56
129S1/SvImJ m 10.5 0.218   10 0.069 0.0208 10.1, 10.8 0.83
A/J f 9.64 0.267   10 0.0846 0.0277 9.3, 10.1 -0.42
A/J m 9.8 0.159   8 0.0561 0.0162 9.43, 9.93 -0.29
AKR/J f 10.4 0.217   10 0.0686 0.0208 10.2, 10.8 0.91
AKR/J m 10.4 0.22   9 0.0735 0.0212 10.1, 10.8 0.67
BALB/cJ f 10.2 0.14   10 0.0442 0.0137 10.0, 10.5 0.56
BALB/cJ m 10.4 0.176   10 0.0558 0.017 10.2, 10.7 0.67
BTBR T+ Itpr3tf/J f 10.4 0.226   9 0.0752 0.0218 9.94, 10.7 0.91
BTBR T+ Itpr3tf/J m 10.6 0.353   10 0.112 0.0334 10.1, 11.2 0.99
BUB/BnJ f 10.2 0.295   9 0.0982 0.0288 9.85, 10.6 0.56
BUB/BnJ m 10.3 0.267   8 0.0944 0.0258 10.0, 10.7 0.51
C3H/HeJ f 10.6 0.22   10 0.0696 0.0207 10.3, 10.9 1.26
C3H/HeJ m 10.7 0.269   10 0.0849 0.0251 10.3, 11.1 1.15
C57BL/6J f 10.2 0.307   10 0.0969 0.0302 9.82, 10.7 0.56
C57BL/6J m 10.3 0.274   10 0.0865 0.0266 9.83, 10.7 0.51
C57L/J f 10.1 0.2   10 0.0631 0.0198 9.84, 10.4 0.38
C57L/J m 10.3 0.294   10 0.0928 0.0284 9.89, 10.8 0.51
C58/J f 9.93 0.217   10 0.0687 0.0219 9.58, 10.3 0.09
C58/J m 10.1 0.119   8 0.0422 0.0118 9.89, 10.3 0.19
CAST/EiJ f 8.73 0.314   9 0.105 0.036 8.3, 9.2 -2.0
CAST/EiJ m 8.66 0.194   9 0.0647 0.0224 8.45, 9.06 -2.1
CZECHII/EiJ f 8.85 0.099   8 0.035 0.0112 8.72, 9.05 -1.79
CZECHII/EiJ m 9.23 0.296   9 0.0986 0.032 8.85, 9.77 -1.19
DBA/2J f 9.98 0.145   10 0.0458 0.0145 9.7, 10.1 0.18
DBA/2J m 10.0 0.279   9 0.093 0.0278 9.55, 10.3 0.03
FVB/NJ f 10.2 0.254   10 0.0803 0.0248 10.0, 10.9 0.56
FVB/NJ m 10.3 0.221   10 0.0699 0.0214 9.92, 10.6 0.51
JF1/MsJ f 9.39 0.446   9 0.149 0.0475 8.66, 10.0 -0.85
JF1/MsJ m 9.17 0.291   9 0.097 0.0317 8.76, 9.72 -1.29
MOLF/EiJ f 8.88 0.189   10 0.0598 0.0213 8.58, 9.2 -1.74
MOLF/EiJ m 8.82 0.142   7 0.0538 0.0161 8.66, 9.0 -1.84
MSM/MsJ f 9.02 0.151   8 0.0534 0.0167 8.79, 9.21 -1.5
MSM/MsJ m 9.0 0.0952   7 0.036 0.0106 8.92, 9.17 -1.56
NOD/ShiLtJ f 10.8 0.0949   10 0.03 0.00876 10.7, 11.0 1.6
NOD/ShiLtJ m 11.2 0.389   10 0.123 0.0347 10.8, 11.9 1.94
NZB/BlNJ f 10.5 0.148   10 0.0467 0.014 10.3, 10.7 1.08
NZB/BlNJ m 10.9 0.329   10 0.104 0.0303 10.2, 11.3 1.46
NZW/LacJ f 10.4 0.44   10 0.139 0.0423 9.62, 11.2 0.91
NZW/LacJ m 10.5 0.298   10 0.0942 0.0284 9.99, 10.9 0.83
PERA/EiJ f 9.82 0.18   8 0.0638 0.0184 9.5, 10.0 -0.1
PERA/EiJ m 9.91 0.167   10 0.0527 0.0168 9.75, 10.2 -0.11
PL/J f 10.5 0.255   10 0.0806 0.0244 10.1, 10.9 1.08
PL/J m 10.4 0.183   9 0.0611 0.0176 10.2, 10.7 0.67
PWK/PhJ f 9.34 0.206   7 0.0778 0.022 9.08, 9.59 -0.94
PWK/PhJ m 9.54 0.235   9 0.0783 0.0246 9.25, 9.97 -0.7
SEA/GnJ f 10.1 0.252   11 0.0761 0.0251 9.72, 10.6 0.38
SEA/GnJ m 9.73 0.342   10 0.108 0.0352 9.33, 10.3 -0.4
SJL/J f 9.76 0.219   10 0.0693 0.0224 9.36, 10.1 -0.21
SJL/J m 9.81 0.205   10 0.0649 0.0209 9.47, 10.1 -0.27
SM/J f 10.1 0.198   9 0.0661 0.0197 9.64, 10.3 0.38
SM/J m 10.2 0.189   10 0.0596 0.0185 9.9, 10.4 0.35
SPRET/EiJ f 9.03 0.21   7 0.0795 0.0233 8.81, 9.43 -1.48
SPRET/EiJ m 9.27 0.435   10 0.138 0.047 8.74, 9.97 -1.13
SWR/J f 9.73 0.191   10 0.0605 0.0197 9.49, 9.99 -0.26
SWR/J m 9.77 0.167   10 0.0527 0.017 9.55, 10.0 -0.33
WSB/EiJ f 9.49 0.372   10 0.118 0.0392 9.02, 10.1 -0.68
WSB/EiJ m 9.6 0.24   8 0.0848 0.025 9.25, 9.92 -0.6


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 10.16 0.0805 10.3181 10.0019
129S1/SvImJ m 10.49 0.0805 10.6481 10.3319
A/J f 9.636 0.0805 9.7941 9.4779
A/J m 9.8038 0.09 9.9805 9.627
AKR/J f 10.44 0.0805 10.5981 10.2819
AKR/J m 10.4111 0.0848 10.5778 10.2445
BALB/cJ f 10.22 0.0805 10.3781 10.0619
BALB/cJ m 10.4 0.0805 10.5581 10.2419
BTBR T+ Itpr3tf/J f 10.36 0.0848 10.5266 10.1934
BTBR T+ Itpr3tf/J m 10.57 0.0805 10.7281 10.4119
BUB/BnJ f 10.2122 0.0848 10.3789 10.0456
BUB/BnJ m 10.3375 0.09 10.5143 10.1607
C3H/HeJ f 10.62 0.0805 10.7781 10.4619
C3H/HeJ m 10.71 0.0805 10.8681 10.5519
C57BL/6J f 10.152 0.0805 10.3101 9.9939
C57BL/6J m 10.273 0.0805 10.4311 10.1149
C57L/J f 10.07 0.0805 10.2281 9.9119
C57L/J m 10.341 0.0805 10.4991 10.1829
C58/J f 9.93 0.0805 10.0881 9.7719
C58/J m 10.1237 0.09 10.3005 9.947
CAST/EiJ f 8.7267 0.0848 8.8933 8.56
CAST/EiJ m 8.6633 0.0848 8.83 8.4967
CZECHII/EiJ f 8.85 0.09 9.0268 8.6732
CZECHII/EiJ m 9.2289 0.0848 9.3955 9.0622
DBA/2J f 9.985 0.0805 10.1431 9.8269
DBA/2J m 10.0344 0.0848 10.2011 9.8678
FVB/NJ f 10.23 0.0805 10.3881 10.0719
FVB/NJ m 10.322 0.0805 10.4801 10.1639
JF1/MsJ f 9.3867 0.0848 9.5533 9.22
JF1/MsJ m 9.1656 0.0848 9.3322 8.9989
MOLF/EiJ f 8.883 0.0805 9.0411 8.7249
MOLF/EiJ m 8.8229 0.0962 9.0118 8.6339
MSM/MsJ f 9.015 0.09 9.1918 8.8382
MSM/MsJ m 9.0029 0.0962 9.1918 8.8139
NOD/ShiLtJ f 10.83 0.0805 10.9881 10.6719
NOD/ShiLtJ m 11.2 0.0805 11.3581 11.0419
NZB/BlNJ f 10.52 0.0805 10.6781 10.3619
NZB/BlNJ m 10.88 0.0805 11.0381 10.7219
NZW/LacJ f 10.396 0.0805 10.5541 10.2379
NZW/LacJ m 10.509 0.0805 10.6671 10.3509
PERA/EiJ f 9.8238 0.09 10.0005 9.647
PERA/EiJ m 9.911 0.0805 10.0691 9.7529
PL/J f 10.45 0.0805 10.6081 10.2919
PL/J m 10.4111 0.0848 10.5778 10.2445
PWK/PhJ f 9.3357 0.0962 9.5247 9.1468
PWK/PhJ m 9.5378 0.0848 9.7044 9.3711
SEA/GnJ f 10.0645 0.0767 10.2153 9.9138
SEA/GnJ m 9.726 0.0805 9.8841 9.5679
SJL/J f 9.763 0.0805 9.9211 9.6049
SJL/J m 9.815 0.0805 9.9731 9.6569
SM/J f 10.0544 0.0848 10.2211 9.8878
SM/J m 10.2 0.0805 10.3581 10.0419
SPRET/EiJ f 9.0271 0.0962 9.2161 8.8382
SPRET/EiJ m 9.269 0.0805 9.4271 9.1109
SWR/J f 9.735 0.0805 9.8931 9.5769
SWR/J m 9.772 0.0805 9.9301 9.6139
WSB/EiJ f 9.489 0.0805 9.6471 9.3309
WSB/EiJ m 9.6038 0.09 9.7805 9.427


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 10.325 0.0569 10.4368 10.2132
A/J both 9.7199 0.0603 9.8384 9.6013
AKR/J both 10.4256 0.0585 10.5404 10.3107
BALB/cJ both 10.31 0.0569 10.4218 10.1982
BTBR T+ Itpr3tf/J both 10.465 0.0585 10.5799 10.3501
BUB/BnJ both 10.2749 0.0618 10.3963 10.1534
C3H/HeJ both 10.665 0.0569 10.7768 10.5532
C57BL/6J both 10.2125 0.0569 10.3243 10.1007
C57L/J both 10.2055 0.0569 10.3173 10.0937
C58/J both 10.0269 0.0603 10.1454 9.9083
CAST/EiJ both 8.695 0.06 8.8128 8.5772
CZECHII/EiJ both 9.0394 0.0618 9.1609 8.918
DBA/2J both 10.0097 0.0585 10.1246 9.8949
FVB/NJ both 10.276 0.0569 10.3878 10.1642
JF1/MsJ both 9.2761 0.06 9.3939 9.1583
MOLF/EiJ both 8.8529 0.0627 8.9761 8.7297
MSM/MsJ both 9.0089 0.0658 9.1383 8.8796
NOD/ShiLtJ both 11.015 0.0569 11.1268 10.9032
NZB/BlNJ both 10.7 0.0569 10.8118 10.5882
NZW/LacJ both 10.4525 0.0569 10.5643 10.3407
PERA/EiJ both 9.8674 0.0603 9.9859 9.7488
PL/J both 10.4306 0.0585 10.5454 10.3157
PWK/PhJ both 9.4367 0.0641 9.5627 9.3108
SEA/GnJ both 9.8953 0.0556 10.0045 9.7861
SJL/J both 9.789 0.0569 9.9008 9.6772
SM/J both 10.1272 0.0585 10.2421 10.0124
SPRET/EiJ both 9.1481 0.0627 9.2713 9.0249
SWR/J both 9.7535 0.0569 9.8653 9.6417
WSB/EiJ both 9.5464 0.0603 9.6649 9.4278




  GWAS USING LINEAR MIXED MODELS