Phenotype measure:   Donahue1   skull_length

ID, description, units MPD:11518   skull_length   total skull length   [mm]
Data set, strains Donahue1   inbred w/CC7   29 strains     sex: both     age: 15-16wks
Procedure DXA
Ontology mappings

  STRAIN COMPARISON PLOT
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Donahue1 - total skull length



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains29 strains
Mean of the strain means22.1   mm 22.4   mm
Median of the strain means22.2   mm 22.6   mm
SD of the strain means± 1.20 ± 1.13
Coefficient of variation (CV)0.0542 0.0504
Min–max range of strain means19.5   –   24.2   mm 19.6   –   23.9   mm
Mean sample size per strain9.5   mice 9.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 12.6932 12.6932 77.7786 < 0.0001
strain 28 666.8874 23.8174 145.9432 < 0.0001
sex:strain 28 10.9621 0.3915 2.399 0.0001
Residuals 485 79.1503 0.1632


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 23.1 0.677   10 0.214 0.0293 21.7, 23.8 0.81
129S1/SvImJ m 23.8 0.264   10 0.0836 0.0111 23.4, 24.2 1.23
A/J f 22.8 0.469   10 0.148 0.0206 22.2, 23.6 0.56
A/J m 23.0 0.374   8 0.132 0.0163 22.4, 23.4 0.53
AKR/J f 23.2 0.35   10 0.111 0.0151 22.8, 23.7 0.9
AKR/J m 22.9 0.18   9 0.0601 0.00786 22.7, 23.3 0.44
BALB/cJ f 23.4 0.408   10 0.129 0.0174 22.7, 23.9 1.06
BALB/cJ m 23.7 0.543   10 0.172 0.0229 22.3, 24.1 1.14
BTBR T+ Itpr3tf/J f 23.9 0.218   9 0.0726 0.00911 23.6, 24.3 1.48
BTBR T+ Itpr3tf/J m 23.9 0.526   10 0.166 0.022 23.3, 24.8 1.32
BUB/BnJ f 22.5 0.439   9 0.146 0.0195 21.8, 23.0 0.31
BUB/BnJ m 22.8 0.4   8 0.141 0.0175 22.1, 23.3 0.35
C3H/HeJ f 21.7 0.655   10 0.207 0.0302 20.5, 22.6 -0.35
C3H/HeJ m 21.9 0.525   10 0.166 0.0239 21.0, 22.6 -0.45
C57BL/6J f 23.3 0.33   10 0.104 0.0142 22.8, 23.9 0.98
C57BL/6J m 23.6 0.563   10 0.178 0.0239 22.3, 24.2 1.06
C57L/J f 22.6 0.615   10 0.194 0.0272 21.5, 23.4 0.4
C57L/J m 22.8 0.523   10 0.165 0.023 21.9, 23.6 0.35
C58/J f 22.9 0.47   10 0.149 0.0205 22.1, 23.4 0.65
C58/J m 23.0 0.247   8 0.0875 0.0108 22.6, 23.4 0.53
CAST/EiJ f 20.1 0.357   9 0.119 0.0177 19.6, 20.5 -1.69
CAST/EiJ m 20.5 0.421   9 0.14 0.0205 19.9, 21.2 -1.69
CZECHII/EiJ f 20.2 0.212   8 0.075 0.0105 19.8, 20.4 -1.61
CZECHII/EiJ m 20.6 0.335   9 0.112 0.0163 19.9, 20.9 -1.6
DBA/2J f 22.0 0.316   10 0.0998 0.0144 21.5, 22.5 -0.1
DBA/2J m 22.6 0.28   9 0.0935 0.0124 22.2, 23.0 0.17
FVB/NJ f 22.6 0.329   10 0.104 0.0146 22.1, 23.0 0.4
FVB/NJ m 23.1 0.262   10 0.0827 0.0113 22.8, 23.5 0.61
JF1/MsJ f 20.4 0.274   9 0.0915 0.0134 20.1, 21.1 -1.44
JF1/MsJ m 20.6 0.46   9 0.153 0.0223 20.2, 21.5 -1.6
MOLF/EiJ f 19.5 0.244   10 0.0772 0.0125 19.0, 19.9 -2.19
MOLF/EiJ m 19.6 0.251   7 0.0948 0.0128 19.3, 20.0 -2.49
MSM/MsJ f 20.4 0.462   8 0.163 0.0226 19.7, 20.9 -1.44
MSM/MsJ m 20.8 0.16   7 0.0606 0.0077 20.7, 21.1 -1.42
NOD/ShiLtJ f 23.1 0.416   10 0.132 0.018 22.7, 24.2 0.81
NOD/ShiLtJ m 23.4 0.497   10 0.157 0.0213 22.4, 24.0 0.88
NZB/BlNJ f 24.2 0.294   10 0.0929 0.0121 23.9, 24.7 1.73
NZB/BlNJ m 23.8 0.479   10 0.152 0.0202 22.9, 24.4 1.23
NZW/LacJ f 23.2 0.368   10 0.116 0.0159 22.5, 23.8 0.9
NZW/LacJ m 23.3 0.341   10 0.108 0.0146 22.8, 23.8 0.79
PERA/EiJ f 21.9 0.321   8 0.113 0.0146 21.3, 22.3 -0.19
PERA/EiJ m 22.4 0.241   10 0.0763 0.0108 21.9, 22.8 -0.01
PL/J f 22.2 0.32   10 0.101 0.0144 21.7, 22.7 0.06
PL/J m 22.6 0.32   9 0.107 0.0142 22.2, 23.2 0.17
PWK/PhJ f 21.8 0.299   7 0.113 0.0138 21.3, 22.2 -0.27
PWK/PhJ m 21.9 0.303   9 0.101 0.0138 21.2, 22.3 -0.45
SEA/GnJ f 22.6 0.64   11 0.193 0.0283 21.4, 23.6 0.4
SEA/GnJ m 22.7 0.458   10 0.145 0.0201 21.8, 23.2 0.26
SJL/J f 22.2 0.485   10 0.153 0.0219 21.6, 23.4 0.06
SJL/J m 22.1 0.288   10 0.0909 0.013 21.7, 22.6 -0.27
SM/J f 21.6 0.484   9 0.161 0.0224 20.9, 22.2 -0.44
SM/J m 22.5 0.283   10 0.0894 0.0126 22.1, 22.9 0.08
SPRET/EiJ f 21.6 0.582   7 0.22 0.0269 21.0, 22.3 -0.44
SPRET/EiJ m 22.1 0.357   10 0.113 0.0162 21.2, 22.6 -0.27
SWR/J f 21.9 0.208   10 0.0657 0.0095 21.6, 22.2 -0.19
SWR/J m 22.6 0.297   10 0.094 0.0131 22.2, 23.0 0.17
WSB/EiJ f 20.7 0.341   10 0.108 0.0165 20.3, 21.4 -1.19
WSB/EiJ m 21.2 0.203   8 0.0718 0.00957 20.9, 21.5 -1.07


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 23.09 0.1277 23.341 22.839
129S1/SvImJ m 23.79 0.1277 24.041 23.539
A/J f 22.83 0.1277 23.081 22.579
A/J m 22.9625 0.1428 23.2431 22.6819
AKR/J f 23.16 0.1277 23.411 22.909
AKR/J m 22.9333 0.1347 23.1979 22.6687
BALB/cJ f 23.43 0.1277 23.681 23.179
BALB/cJ m 23.68 0.1277 23.931 23.429
BTBR T+ Itpr3tf/J f 23.9333 0.1347 24.1979 23.6687
BTBR T+ Itpr3tf/J m 23.91 0.1277 24.161 23.659
BUB/BnJ f 22.4667 0.1347 22.7313 22.2021
BUB/BnJ m 22.8 0.1428 23.0806 22.5194
C3H/HeJ f 21.67 0.1277 21.921 21.419
C3H/HeJ m 21.93 0.1277 22.181 21.679
C57BL/6J f 23.33 0.1277 23.581 23.079
C57BL/6J m 23.58 0.1277 23.831 23.329
C57L/J f 22.57 0.1277 22.821 22.319
C57L/J m 22.77 0.1277 23.021 22.519
C58/J f 22.89 0.1277 23.141 22.639
C58/J m 23.0125 0.1428 23.2931 22.7319
CAST/EiJ f 20.1333 0.1347 20.3979 19.8687
CAST/EiJ m 20.5222 0.1347 20.7868 20.2576
CZECHII/EiJ f 20.175 0.1428 20.4556 19.8944
CZECHII/EiJ m 20.6333 0.1347 20.8979 20.3687
DBA/2J f 21.98 0.1277 22.231 21.729
DBA/2J m 22.5889 0.1347 22.8535 22.3243
FVB/NJ f 22.58 0.1277 22.831 22.329
FVB/NJ m 23.12 0.1277 23.371 22.869
JF1/MsJ f 20.4444 0.1347 20.709 20.1799
JF1/MsJ m 20.6222 0.1347 20.8868 20.3576
MOLF/EiJ f 19.52 0.1277 19.771 19.269
MOLF/EiJ m 19.6429 0.1527 19.9429 19.3428
MSM/MsJ f 20.425 0.1428 20.7056 20.1444
MSM/MsJ m 20.8286 0.1527 21.1286 20.5286
NOD/ShiLtJ f 23.1 0.1277 23.351 22.849
NOD/ShiLtJ m 23.37 0.1277 23.621 23.119
NZB/BlNJ f 24.18 0.1277 24.431 23.929
NZB/BlNJ m 23.79 0.1277 24.041 23.539
NZW/LacJ f 23.23 0.1277 23.481 22.979
NZW/LacJ m 23.34 0.1277 23.591 23.089
PERA/EiJ f 21.9 0.1428 22.1806 21.6194
PERA/EiJ m 22.44 0.1277 22.691 22.189
PL/J f 22.17 0.1277 22.421 21.919
PL/J m 22.6 0.1347 22.8646 22.3354
PWK/PhJ f 21.7571 0.1527 22.0572 21.4571
PWK/PhJ m 21.9222 0.1347 22.1868 21.6576
SEA/GnJ f 22.6273 0.1218 22.8666 22.3879
SEA/GnJ m 22.74 0.1277 22.991 22.489
SJL/J f 22.2 0.1277 22.451 21.949
SJL/J m 22.06 0.1277 22.311 21.809
SM/J f 21.6222 0.1347 21.8868 21.3576
SM/J m 22.5 0.1277 22.751 22.249
SPRET/EiJ f 21.6286 0.1527 21.9286 21.3286
SPRET/EiJ m 22.05 0.1277 22.301 21.799
SWR/J f 21.89 0.1277 22.141 21.639
SWR/J m 22.62 0.1277 22.871 22.369
WSB/EiJ f 20.69 0.1277 20.941 20.439
WSB/EiJ m 21.2125 0.1428 21.4931 20.9319


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 23.44 0.0903 23.6175 23.2625
A/J both 22.8963 0.0958 23.0845 22.708
AKR/J both 23.0467 0.0928 23.229 22.8643
BALB/cJ both 23.555 0.0903 23.7325 23.3775
BTBR T+ Itpr3tf/J both 23.9217 0.0928 24.104 23.7393
BUB/BnJ both 22.6333 0.0981 22.8262 22.4405
C3H/HeJ both 21.8 0.0903 21.9775 21.6225
C57BL/6J both 23.455 0.0903 23.6325 23.2775
C57L/J both 22.67 0.0903 22.8475 22.4925
C58/J both 22.9513 0.0958 23.1395 22.763
CAST/EiJ both 20.3278 0.0952 20.5149 20.1407
CZECHII/EiJ both 20.4042 0.0981 20.597 20.2113
DBA/2J both 22.2844 0.0928 22.4668 22.1021
FVB/NJ both 22.85 0.0903 23.0275 22.6725
JF1/MsJ both 20.5333 0.0952 20.7204 20.3462
MOLF/EiJ both 19.5814 0.0995 19.777 19.3858
MSM/MsJ both 20.6268 0.1045 20.8322 20.4214
NOD/ShiLtJ both 23.235 0.0903 23.4125 23.0575
NZB/BlNJ both 23.985 0.0903 24.1625 23.8075
NZW/LacJ both 23.285 0.0903 23.4625 23.1075
PERA/EiJ both 22.17 0.0958 22.3583 21.9817
PL/J both 22.385 0.0928 22.5674 22.2026
PWK/PhJ both 21.8397 0.1018 22.0397 21.6397
SEA/GnJ both 22.6836 0.0883 22.857 22.5102
SJL/J both 22.13 0.0903 22.3075 21.9525
SM/J both 22.0611 0.0928 22.2435 21.8788
SPRET/EiJ both 21.8393 0.0995 22.0349 21.6437
SWR/J both 22.255 0.0903 22.4325 22.0775
WSB/EiJ both 20.9513 0.0958 21.1395 20.763




  GWAS USING LINEAR MIXED MODELS