Phenotype measure:   Donahue1   body_BMC

ID, description, units MPD:11508   body_BMC   whole body bone mineral content (BMC)   [g]
Data set, strains Donahue1   inbred w/CC7   30 strains     sex: both     age: 15-16wks
Procedure DXA
Ontology mappings

  STRAIN COMPARISON PLOT
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Donahue1 - whole body bone mineral content (BMC)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested30 strains30 strains
Mean of the strain means0.386   g 0.409   g
Median of the strain means0.391   g 0.443   g
SD of the strain means± 0.0921 ± 0.0966
Coefficient of variation (CV)0.239 0.236
Min–max range of strain means0.247   –   0.585   g 0.254   –   0.546   g
Mean sample size per strain10.2   mice 9.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.1081 0.1081 112.7422 < 0.0001
strain 29 4.9099 0.1693 176.5944 < 0.0001
sex:strain 29 0.2563 0.0088 9.2184 < 0.0001
Residuals 547 0.5244 0.001


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.506 0.0364   10 0.0115 0.0721 0.425, 0.563 1.31
129S1/SvImJ m 0.532 0.0398   10 0.0126 0.0747 0.471, 0.587 1.27
129X1/SvJ f 0.474 0.0374   10 0.0118 0.0789 0.405, 0.547 0.96
129X1/SvJ m 0.505 0.0341   10 0.0108 0.0674 0.443, 0.546 0.99
A/J f 0.318 0.0269   10 0.00849 0.0845 0.287, 0.374 -0.73
A/J m 0.359 0.0202   10 0.00638 0.0562 0.327, 0.39 -0.52
AKR/J f 0.518 0.0356   10 0.0113 0.0687 0.484, 0.577 1.44
AKR/J m 0.521 0.0273   10 0.00862 0.0524 0.46, 0.567 1.16
BALB/cJ f 0.42 0.0353   10 0.0112 0.0841 0.379, 0.482 0.37
BALB/cJ m 0.468 0.0235   10 0.00744 0.0502 0.439, 0.502 0.61
BTBR T+ Itpr3tf/J f 0.585 0.0356   9 0.0119 0.0608 0.537, 0.648 2.17
BTBR T+ Itpr3tf/J m 0.546 0.0438   10 0.0139 0.0802 0.457, 0.614 1.42
BUB/BnJ f 0.479 0.0197   10 0.00623 0.0411 0.444, 0.507 1.01
BUB/BnJ m 0.495 0.0209   10 0.0066 0.0422 0.464, 0.526 0.89
C3H/HeJ f 0.473 0.0359   10 0.0114 0.0759 0.427, 0.543 0.95
C3H/HeJ m 0.499 0.0313   10 0.00989 0.0628 0.45, 0.542 0.93
C57BL/6J f 0.381 0.0307   10 0.0097 0.0806 0.342, 0.421 -0.05
C57BL/6J m 0.461 0.027   10 0.00854 0.0586 0.419, 0.496 0.54
C57L/J f 0.47 0.0376   10 0.0119 0.08 0.39, 0.517 0.92
C57L/J m 0.456 0.0404   10 0.0128 0.0886 0.405, 0.523 0.49
C58/J f 0.417 0.0382   10 0.0121 0.0916 0.378, 0.498 0.34
C58/J m 0.407 0.0323   9 0.0108 0.0794 0.361, 0.46 -0.02
CAST/EiJ f 0.292 0.0225   10 0.0071 0.0768 0.256, 0.332 -1.02
CAST/EiJ m 0.284 0.0195   10 0.00617 0.0686 0.26, 0.323 -1.29
CZECHII/EiJ f 0.248 0.0375   12 0.0108 0.151 0.196, 0.312 -1.49
CZECHII/EiJ m 0.274 0.0301   12 0.00869 0.11 0.229, 0.311 -1.4
DBA/2J f 0.358 0.0106   10 0.00337 0.0297 0.341, 0.372 -0.3
DBA/2J m 0.375 0.0235   10 0.00743 0.0627 0.344, 0.411 -0.35
FVB/NJ f 0.405 0.0209   10 0.0066 0.0516 0.386, 0.442 0.21
FVB/NJ m 0.48 0.0322   10 0.0102 0.067 0.425, 0.541 0.73
JF1/MsJ f 0.267 0.0279   11 0.00842 0.105 0.233, 0.317 -1.29
JF1/MsJ m 0.254 0.0237   10 0.00751 0.0934 0.221, 0.287 -1.6
MOLF/EiJ f 0.272 0.03   10 0.00947 0.11 0.231, 0.318 -1.23
MOLF/EiJ m 0.259 0.0193   8 0.00683 0.0746 0.235, 0.288 -1.55
MSM/MsJ f 0.267 0.0307   11 0.00925 0.115 0.224, 0.324 -1.29
MSM/MsJ m 0.266 0.0406   9 0.0135 0.153 0.228, 0.334 -1.48
NOD/ShiLtJ f 0.457 0.0228   10 0.00722 0.05 0.416, 0.501 0.78
NOD/ShiLtJ m 0.499 0.0343   10 0.0109 0.0688 0.413, 0.539 0.93
NZB/BlNJ f 0.473 0.0235   10 0.00743 0.0497 0.431, 0.516 0.95
NZB/BlNJ m 0.449 0.0354   10 0.0112 0.0788 0.396, 0.511 0.41
NZW/LacJ f 0.453 0.0282   10 0.00891 0.0622 0.416, 0.497 0.73
NZW/LacJ m 0.532 0.0327   10 0.0104 0.0615 0.482, 0.585 1.27
PERA/EiJ f 0.327 0.0403   10 0.0128 0.123 0.283, 0.427 -0.64
PERA/EiJ m 0.469 0.0371   10 0.0117 0.0792 0.392, 0.519 0.62
PL/J f 0.341 0.0232   10 0.00733 0.068 0.292, 0.364 -0.48
PL/J m 0.362 0.0293   11 0.00882 0.0808 0.318, 0.425 -0.49
PWK/PhJ f 0.337 0.0453   13 0.0126 0.134 0.287, 0.42 -0.53
PWK/PhJ m 0.304 0.0383   9 0.0128 0.126 0.256, 0.371 -1.09
SEA/GnJ f 0.401 0.0358   14 0.00957 0.0894 0.354, 0.464 0.17
SEA/GnJ m 0.397 0.0417   10 0.0132 0.105 0.341, 0.484 -0.12
SJL/J f 0.435 0.0292   10 0.00923 0.0671 0.382, 0.486 0.54
SJL/J m 0.474 0.0292   10 0.00922 0.0616 0.431, 0.519 0.67
SM/J f 0.247 0.0247   10 0.00782 0.1 0.193, 0.276 -1.5
SM/J m 0.327 0.0228   10 0.0072 0.0697 0.287, 0.377 -0.85
SPRET/EiJ f 0.317 0.028   9 0.00933 0.0883 0.282, 0.368 -0.74
SPRET/EiJ m 0.28 0.0215   10 0.00681 0.0769 0.258, 0.327 -1.34
SWR/J f 0.362 0.0112   10 0.00354 0.0309 0.339, 0.375 -0.26
SWR/J m 0.436 0.0217   10 0.00685 0.0496 0.406, 0.48 0.28
WSB/EiJ f 0.267 0.0272   10 0.0086 0.102 0.221, 0.312 -1.29
WSB/EiJ m 0.301 0.0287   10 0.00907 0.0954 0.267, 0.363 -1.12


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.5058 0.0098 0.525 0.4866
129S1/SvImJ m 0.5322 0.0098 0.5514 0.513
129X1/SvJ f 0.4743 0.0098 0.4935 0.4551
129X1/SvJ m 0.5054 0.0098 0.5246 0.4862
A/J f 0.3178 0.0098 0.337 0.2986
A/J m 0.3591 0.0098 0.3783 0.3399
AKR/J f 0.5183 0.0098 0.5375 0.4991
AKR/J m 0.5209 0.0098 0.5401 0.5017
BALB/cJ f 0.4196 0.0098 0.4388 0.4004
BALB/cJ m 0.4682 0.0098 0.4874 0.449
BTBR T+ Itpr3tf/J f 0.5852 0.0103 0.6055 0.5649
BTBR T+ Itpr3tf/J m 0.5464 0.0098 0.5656 0.5272
BUB/BnJ f 0.4795 0.0098 0.4987 0.4603
BUB/BnJ m 0.4948 0.0098 0.514 0.4756
C3H/HeJ f 0.4734 0.0098 0.4926 0.4542
C3H/HeJ m 0.4985 0.0098 0.5177 0.4793
C57BL/6J f 0.3805 0.0098 0.3997 0.3613
C57BL/6J m 0.4608 0.0098 0.48 0.4416
C57L/J f 0.4697 0.0098 0.4889 0.4505
C57L/J m 0.4563 0.0098 0.4755 0.4371
C58/J f 0.4173 0.0098 0.4365 0.3981
C58/J m 0.4068 0.0103 0.4271 0.3865
CAST/EiJ f 0.2922 0.0098 0.3114 0.273
CAST/EiJ m 0.2842 0.0098 0.3034 0.265
CZECHII/EiJ f 0.2476 0.0089 0.2651 0.23
CZECHII/EiJ m 0.274 0.0089 0.2916 0.2564
DBA/2J f 0.3583 0.0098 0.3775 0.3391
DBA/2J m 0.3748 0.0098 0.394 0.3556
FVB/NJ f 0.4047 0.0098 0.4239 0.3855
FVB/NJ m 0.4805 0.0098 0.4997 0.4613
JF1/MsJ f 0.2667 0.0093 0.2851 0.2484
JF1/MsJ m 0.2543 0.0098 0.2735 0.2351
MOLF/EiJ f 0.2717 0.0098 0.2909 0.2525
MOLF/EiJ m 0.259 0.0109 0.2805 0.2375
MSM/MsJ f 0.2667 0.0093 0.2851 0.2484
MSM/MsJ m 0.266 0.0103 0.2863 0.2457
NOD/ShiLtJ f 0.4571 0.0098 0.4763 0.4379
NOD/ShiLtJ m 0.4989 0.0098 0.5181 0.4797
NZB/BlNJ f 0.473 0.0098 0.4922 0.4538
NZB/BlNJ m 0.4488 0.0098 0.468 0.4296
NZW/LacJ f 0.4531 0.0098 0.4723 0.4339
NZW/LacJ m 0.5318 0.0098 0.551 0.5126
PERA/EiJ f 0.3272 0.0098 0.3464 0.308
PERA/EiJ m 0.4691 0.0098 0.4883 0.4499
PL/J f 0.341 0.0098 0.3602 0.3218
PL/J m 0.3622 0.0093 0.3805 0.3438
PWK/PhJ f 0.3366 0.0086 0.3535 0.3197
PWK/PhJ m 0.3038 0.0103 0.3241 0.2835
SEA/GnJ f 0.4006 0.0083 0.4169 0.3844
SEA/GnJ m 0.3974 0.0098 0.4166 0.3782
SJL/J f 0.4349 0.0098 0.4541 0.4157
SJL/J m 0.4737 0.0098 0.4929 0.4545
SM/J f 0.2465 0.0098 0.2657 0.2273
SM/J m 0.3268 0.0098 0.346 0.3076
SPRET/EiJ f 0.317 0.0103 0.3373 0.2967
SPRET/EiJ m 0.2801 0.0098 0.2993 0.2609
SWR/J f 0.3618 0.0098 0.381 0.3426
SWR/J m 0.4361 0.0098 0.4553 0.4169
WSB/EiJ f 0.267 0.0098 0.2862 0.2478
WSB/EiJ m 0.3007 0.0098 0.3199 0.2815


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.519 0.0069 0.5326 0.5054
129X1/SvJ both 0.4899 0.0069 0.5035 0.4762
A/J both 0.3384 0.0069 0.3521 0.3248
AKR/J both 0.5196 0.0069 0.5332 0.506
BALB/cJ both 0.4439 0.0069 0.4575 0.4303
BTBR T+ Itpr3tf/J both 0.5658 0.0071 0.5798 0.5518
BUB/BnJ both 0.4871 0.0069 0.5008 0.4735
C3H/HeJ both 0.486 0.0069 0.4996 0.4723
C57BL/6J both 0.4207 0.0069 0.4343 0.407
C57L/J both 0.463 0.0069 0.4766 0.4494
C58/J both 0.412 0.0071 0.426 0.3981
CAST/EiJ both 0.2882 0.0069 0.3018 0.2746
CZECHII/EiJ both 0.2608 0.0063 0.2732 0.2484
DBA/2J both 0.3666 0.0069 0.3802 0.3529
FVB/NJ both 0.4426 0.0069 0.4562 0.429
JF1/MsJ both 0.2605 0.0068 0.2738 0.2472
MOLF/EiJ both 0.2654 0.0073 0.2798 0.2509
MSM/MsJ both 0.2664 0.007 0.28 0.2527
NOD/ShiLtJ both 0.478 0.0069 0.4916 0.4644
NZB/BlNJ both 0.4609 0.0069 0.4745 0.4473
NZW/LacJ both 0.4925 0.0069 0.5061 0.4788
PERA/EiJ both 0.3982 0.0069 0.4118 0.3845
PL/J both 0.3516 0.0068 0.3649 0.3383
PWK/PhJ both 0.3202 0.0067 0.3334 0.307
SEA/GnJ both 0.399 0.0064 0.4116 0.3864
SJL/J both 0.4543 0.0069 0.4679 0.4407
SM/J both 0.2867 0.0069 0.3003 0.273
SPRET/EiJ both 0.2985 0.0071 0.3125 0.2846
SWR/J both 0.399 0.0069 0.4126 0.3853
WSB/EiJ both 0.2839 0.0069 0.2975 0.2702




  GWAS USING LINEAR MIXED MODELS