Project measure / variable:   Bennett4   BET_post_HFHS

ID, description, units MPD:114776   BET_post_HFHS   plasma betaine amount, post-diet   [µM]  HFHS group  
various diets 2 study
Data set, strains Bennett4   CC   22 strains     sex: f     age: 17-20wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Bennett4 - plasma betaine amount, post-diet HFHS group



  MEASURE SUMMARY
Measure Summary Female
Number of strains tested22 strains
Mean of the strain means56.73   µM
Median of the strain means54.41   µM
SD of the strain means± 14.288
Coefficient of variation (CV)0.2519
Min–max range of strain means36.24   –   87.38   µM
Mean sample size per strain4.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 21 18636.0877 887.4327 4.1597 < 0.0001
Residuals 76 16213.8762 213.3405


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
CC001/Unc f 58.79 10.28   5 4.5975 0.1749 47.0, 69.7 0.14
CC002/Unc f 74.34 11.639   5 5.2052 0.1566 54.2, 82.8 1.23
CC004/TauUnc f 49.78 8.0466   5 3.5985 0.1616 38.1, 60.0 -0.49
CC006/TauUnc f 44.65 9.588   4 4.794 0.2147 32.3, 55.7 -0.85
CC008/GeniUnc f 64.28 9.2464   4 4.6232 0.1439 52.3, 74.6 0.53
CC011/Unc f 52.08 13.468   5 6.0232 0.2586 39.0, 72.5 -0.33
CC012/GeniUnc f 57.24 14.908   5 6.667 0.2604 44.6, 82.2 0.04
CC019/TauUnc f 52.7 13.682   5 6.1188 0.2596 29.0, 62.0 -0.28
CC024/GeniUnc f 73.15 11.384   2   8.05 0.1556 65.1, 81.2 1.15
CC027/GeniUnc f 50.34 17.411   5 7.7863 0.3459 32.1, 72.2 -0.45
CC028/GeniUnc f 87.38 12.133   4 6.0665 0.1389 69.9, 97.3 2.15
CC030/GeniUnc f 42.78 14.813   5 6.6245 0.3463 22.2, 61.7 -0.98
CC032/GeniUnc f 36.24 19.004   5 8.4987 0.5244 25.1, 70.0 -1.43
CC035/Unc f 56.12 15.535   5 6.9473 0.2768 47.5, 83.8 -0.04
CC036/Unc f 84.94 19.4   5 8.676 0.2284 65.8, 117.6 1.97
CC037/TauUnc f 43.92 8.0434   5 3.5971 0.1831 32.3, 54.2 -0.9
CC040/TauUnc f 39.775 22.605   4 11.302 0.5683 7.3, 58.8 -1.19
CC041/TauUnc f 57.66 25.853   5 11.562 0.4484 35.7, 102.0 0.07
CC045/GeniUnc f 51.25 13.261   4 6.6305 0.2588 40.5, 70.6 -0.38
CC059/TauUnc f 38.92 6.0235   5 2.6938 0.1548 30.1, 44.3 -1.25
CC063/Unc f 60.43 11.585   3 6.6889 0.1917 51.8, 73.6 0.26
CC071/TauUnc f 71.2 7.4646   3 4.3097 0.1048 66.4, 79.8 1.01


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
CC001/Unc f 58.79 6.5320819939 71.7997687913 45.7802312087
CC002/Unc f 74.34 6.5320819939 87.3497687913 61.3302312087
CC004/TauUnc f 49.78 6.5320819939 62.7897687913 36.7702312087
CC006/TauUnc f 44.65 7.3030896865 59.1953636944 30.1046363056
CC008/GeniUnc f 64.275 7.3030896865 78.8203636944 49.7296363056
CC011/Unc f 52.08 6.5320819939 65.0897687913 39.0702312087
CC012/GeniUnc f 57.24 6.5320819939 70.2497687913 44.2302312087
CC019/TauUnc f 52.7 6.5320819939 65.7097687913 39.6902312087
CC024/GeniUnc f 73.15 10.3281284819 93.7202506063 52.5797493937
CC027/GeniUnc f 50.34 6.5320819939 63.3497687913 37.3302312087
CC028/GeniUnc f 87.375 7.3030896865 101.9203636944 72.8296363056
CC030/GeniUnc f 42.78 6.5320819939 55.7897687913 29.7702312087
CC032/GeniUnc f 36.24 6.5320819939 49.2497687913 23.2302312087
CC035/Unc f 56.12 6.5320819939 69.1297687913 43.1102312087
CC036/Unc f 84.94 6.5320819939 97.9497687913 71.9302312087
CC037/TauUnc f 43.92 6.5320819939 56.9297687913 30.9102312087
CC040/TauUnc f 39.775 7.3030896865 54.3203636944 25.2296363056
CC041/TauUnc f 57.66 6.5320819939 70.6697687913 44.6502312087
CC045/GeniUnc f 51.25 7.3030896865 65.7953636944 36.7046363056
CC059/TauUnc f 38.92 6.5320819939 51.9297687913 25.9102312087
CC063/Unc f 60.4333333333 8.4328815929 77.2288726222 43.6377940445
CC071/TauUnc f 71.2 8.4328815929 87.9955392889 54.4044607111




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA