Project measure / variable:   Bennett4   BET_base_HFHS

ID, description, units MPD:114774   BET_base_HFHS   plasma betaine amount, baseline   [µM]  HFHS group  
various diets 2 study
Data set, strains Bennett4   CC   22 strains     sex: f     age: 8-11wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Bennett4 - plasma betaine amount, baseline HFHS group



  MEASURE SUMMARY
Measure Summary Female
Number of strains tested22 strains
Mean of the strain means49.17   µM
Median of the strain means43.47   µM
SD of the strain means± 16.18
Coefficient of variation (CV)0.3291
Min–max range of strain means27.52   –   96.85   µM
Mean sample size per strain4.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 21 18532.2557 882.4884 6.9886 < 0.0001
Residuals 79 9975.7827 126.2757


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
CC001/Unc f 43.06 9.6513   5 4.3162 0.2241 31.1, 56.7 -0.38
CC002/Unc f 56.42 15.308   5 6.8458 0.2713 39.3, 74.6 0.45
CC004/TauUnc f 40.88 8.9703   5 4.0117 0.2194 30.8, 52.2 -0.51
CC006/TauUnc f 39.1 12.759   4 6.3794 0.3263 27.4, 57.2 -0.62
CC008/GeniUnc f 61.73 12.216   4 6.1081 0.1979 52.1, 79.0 0.78
CC011/Unc f 36.24 15.47   5 6.9184 0.4269 10.1, 46.4 -0.8
CC012/GeniUnc f 42.34 6.3086   5 2.8213 0.149 33.8, 50.8 -0.42
CC019/TauUnc f 34.24 6.5653   5 2.9361 0.1917 26.4, 39.5 -0.92
CC024/GeniUnc f 96.85 12.516   2   8.85 0.1292 88.0, 105.7 2.95
CC027/GeniUnc f 46.02 4.5784   5 2.0475 0.0995 40.5, 52.6 -0.19
CC028/GeniUnc f 85.4 13.947   4 6.9734 0.1633 64.8, 95.7 2.24
CC030/GeniUnc f 41.58 5.2438   5 2.3451 0.1261 35.3, 46.4 -0.47
CC032/GeniUnc f 27.52 6.0981   5 2.7272 0.2216 20.5, 35.7 -1.34
CC035/Unc f 46.84 6.6909   5 2.9923 0.1428 37.6, 56.5 -0.14
CC036/Unc f 45.76 6.8208   5 3.0503 0.1491 35.2, 53.6 -0.21
CC037/TauUnc f 42.28 15.396   5 6.8854 0.3642 33.4, 69.5 -0.43
CC040/TauUnc f 42.86 15.355   5 6.8668 0.3583 30.6, 69.4 -0.39
CC041/TauUnc f 43.88 16.051   5 7.1782 0.3658 26.7, 69.1 -0.33
CC045/GeniUnc f 40.425 6.8665   4 3.4333 0.1699 31.4, 47.4 -0.54
CC059/TauUnc f 46.42 7.1921   5 3.2164 0.1549 38.5, 55.2 -0.17
CC063/Unc f 57.27 8.7752   3 5.0663 0.1532 47.2, 63.3 0.5
CC071/TauUnc f 64.62 17.657   5 7.8962 0.2732 48.2, 92.8 0.95


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
CC001/Unc f 43.06 5.0254498298 53.0629076702 33.0570923298
CC002/Unc f 56.42 5.0254498298 66.4229076702 46.4170923298
CC004/TauUnc f 40.88 5.0254498298 50.8829076702 30.8770923298
CC006/TauUnc f 39.1 5.6186237184 50.2835907616 27.9164092384
CC008/GeniUnc f 61.725 5.6186237184 72.9085907616 50.5414092384
CC011/Unc f 36.24 5.0254498298 46.2429076702 26.2370923298
CC012/GeniUnc f 42.34 5.0254498298 52.3429076702 32.3370923298
CC019/TauUnc f 34.24 5.0254498298 44.2429076702 24.2370923298
CC024/GeniUnc f 96.85 7.9459338645 112.6659857311 81.0340142689
CC027/GeniUnc f 46.02 5.0254498298 56.0229076702 36.0170923298
CC028/GeniUnc f 85.4 5.6186237184 96.5835907616 74.2164092384
CC030/GeniUnc f 41.58 5.0254498298 51.5829076702 31.5770923298
CC032/GeniUnc f 27.52 5.0254498298 37.5229076702 17.5170923298
CC035/Unc f 46.84 5.0254498298 56.8429076702 36.8370923298
CC036/Unc f 45.76 5.0254498298 55.7629076702 35.7570923298
CC037/TauUnc f 42.28 5.0254498298 52.2829076702 32.2770923298
CC040/TauUnc f 42.86 5.0254498298 52.8629076702 32.8570923298
CC041/TauUnc f 43.88 5.0254498298 53.8829076702 33.8770923298
CC045/GeniUnc f 40.425 5.6186237184 51.6085907616 29.2414092384
CC059/TauUnc f 46.42 5.0254498298 56.4229076702 36.4170923298
CC063/Unc f 57.2666666667 6.4878278326 70.1803649401 44.3529683933
CC071/TauUnc f 64.62 5.0254498298 74.6229076702 54.6170923298




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA