Project measure / variable:   Bennett4   BET_base_HP

ID, description, units MPD:114773   BET_base_HP   plasma betaine amount, baseline   [µM]  HP group  
various diets 2 study
Data set, strains Bennett4   CC   22 strains     sex: f     age: 8-11wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Bennett4 - plasma betaine amount, baseline HP group



  MEASURE SUMMARY
Measure Summary Female
Number of strains tested22 strains
Mean of the strain means49.785   µM
Median of the strain means44.91   µM
SD of the strain means± 17.055
Coefficient of variation (CV)0.3426
Min–max range of strain means33.9   –   104.2   µM
Mean sample size per strain4.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 21 19712.0301 938.6681 7.9306 < 0.0001
Residuals 79 9350.4442 118.3601


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
CC001/Unc f 42.22 7.003   5 3.1318 0.1659 31.4, 48.4 -0.44
CC002/Unc f 62.96 12.299   5 5.5003 0.1953 48.2, 78.4 0.77
CC004/TauUnc f 43.74 6.4345   5 2.8776 0.1471 35.1, 51.2 -0.35
CC006/TauUnc f 49.75 7.1636   4 3.5818 0.144 39.7, 56.3 0.0
CC008/GeniUnc f 48.05 14.236   4 7.1179 0.2963 27.2, 59.1 -0.1
CC011/Unc f 53.28 11.224   5 5.0197 0.2107 34.0, 63.3 0.2
CC012/GeniUnc f 40.86 16.261   5 7.2722 0.398 20.7, 60.9 -0.52
CC019/TauUnc f 34.14 5.2291   5 2.3385 0.1532 28.5, 39.5 -0.92
CC024/GeniUnc f 104.2 31.961   2   22.6 0.3067 81.6, 126.8 3.19
CC027/GeniUnc f 46.08 12.887   5 5.7635 0.2797 25.3, 58.8 -0.22
CC028/GeniUnc f 88.62 10.185   4 5.0927 0.1149 73.5, 95.7 2.28
CC030/GeniUnc f 40.26 7.2238   5 3.2306 0.1794 33.7, 52.4 -0.56
CC032/GeniUnc f 35.08 7.2489   5 3.2418 0.2066 25.8, 43.6 -0.86
CC035/Unc f 52.62 12.123   5 5.4217 0.2304 42.3, 73.5 0.17
CC036/Unc f 53.62 13.363   5 5.9759 0.2492 38.3, 64.9 0.22
CC037/TauUnc f 33.9 4.7497   5 2.1241 0.1401 28.4, 39.6 -0.93
CC040/TauUnc f 38.56 10.615   5 4.7474 0.2753 24.1, 49.9 -0.66
CC041/TauUnc f 40.64 10.176   5 4.5507 0.2504 30.0, 56.5 -0.54
CC045/GeniUnc f 40.85 9.6265   4 4.8133 0.2357 26.9, 48.8 -0.52
CC059/TauUnc f 40.3 7.2364   5 3.2362 0.1796 31.8, 51.6 -0.56
CC063/Unc f 48.367 12.716   3 7.3417 0.2629 40.0, 63.0 -0.08
CC071/TauUnc f 57.18 10.799   5 4.8294 0.1889 42.1, 71.9 0.43


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
CC001/Unc f 42.22 4.8653890439 51.9043146453 32.5356853547
CC002/Unc f 62.96 4.8653890439 72.6443146453 53.2756853547
CC004/TauUnc f 43.74 4.8653890439 53.4243146453 34.0556853547
CC006/TauUnc f 49.75 5.4396703196 60.5773929312 38.9226070688
CC008/GeniUnc f 48.05 5.4396703196 58.8773929312 37.2226070688
CC011/Unc f 53.28 4.8653890439 62.9643146453 43.5956853547
CC012/GeniUnc f 40.86 4.8653890439 50.5443146453 31.1756853547
CC019/TauUnc f 34.14 4.8653890439 43.8243146453 24.4556853547
CC024/GeniUnc f 104.2 7.6928555408 119.5122459284 88.8877540716
CC027/GeniUnc f 46.08 4.8653890439 55.7643146453 36.3956853547
CC028/GeniUnc f 88.625 5.4396703196 99.4523929312 77.7976070688
CC030/GeniUnc f 40.26 4.8653890439 49.9443146453 30.5756853547
CC032/GeniUnc f 35.08 4.8653890439 44.7643146453 25.3956853547
CC035/Unc f 52.62 4.8653890439 62.3043146453 42.9356853547
CC036/Unc f 53.62 4.8653890439 63.3043146453 43.9356853547
CC037/TauUnc f 33.9 4.8653890439 43.5843146453 24.2156853547
CC040/TauUnc f 38.56 4.8653890439 48.2443146453 28.8756853547
CC041/TauUnc f 40.64 4.8653890439 50.3243146453 30.9556853547
CC045/GeniUnc f 40.85 5.4396703196 51.6773929312 30.0226070688
CC059/TauUnc f 40.3 4.8653890439 49.9843146453 30.6156853547
CC063/Unc f 48.3666666667 6.2811902466 60.8690631135 35.8642702198
CC071/TauUnc f 57.18 4.8653890439 66.8643146453 47.4956853547




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA