Project measure / variable:   Bennett4   TMAO_base_HP

ID, description, units MPD:114765   TMAO_base_HP   plasma trimethylamine N-oxide (TMAO) amount, baseline   [µM]  HP group  
various diets 2 study
Data set, strains Bennett4   CC   22 strains     sex: f     age: 8-11wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Bennett4 - plasma trimethylamine N-oxide (TMAO) amount, baseline HP group



  MEASURE SUMMARY
Measure Summary Female
Number of strains tested22 strains
Mean of the strain means5.3281   µM
Median of the strain means4.385   µM
SD of the strain means± 3.876
Coefficient of variation (CV)0.7275
Min–max range of strain means0.7   –   14.84   µM
Mean sample size per strain4.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 21 1394.0154 66.3817 5.2238 < 0.0001
Residuals 79 1003.8922 12.7075


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
CC001/Unc f 2.58 1.2029   5 0.53796 0.4662 1.1, 4.4 -0.71
CC002/Unc f 4.14 0.80498   5 0.36 0.1944 3.2, 5.3 -0.31
CC004/TauUnc f 3.1 2.4729   5 1.1059 0.7977 0.8, 7.3 -0.57
CC006/TauUnc f 4.925 2.3386   4 1.1693 0.4748 2.7, 8.2 -0.1
CC008/GeniUnc f 1.425 0.55   4 0.275 0.386 0.6, 1.7 -1.01
CC011/Unc f 2.5 0.5244   5 0.23452 0.2098 1.9, 3.1 -0.73
CC012/GeniUnc f 4.68 1.5579   5 0.69671 0.3329 2.9, 6.6 -0.17
CC019/TauUnc f 5.38 3.665   5 1.639 0.6812 1.8, 11.0 0.01
CC024/GeniUnc f 4.15 1.0607   2   0.75 0.2556 3.4, 4.9 -0.3
CC027/GeniUnc f 3.78 2.2016   5 0.98458 0.5824 1.8, 6.6 -0.4
CC028/GeniUnc f 1.475 0.20616   4 0.10308 0.1398 1.2, 1.7 -0.99
CC030/GeniUnc f 6.2 2.9933   5 1.3387 0.4828 2.7, 10.4 0.22
CC032/GeniUnc f 7.56 3.5522   5 1.5886 0.4699 3.5, 11.7 0.58
CC035/Unc f 14.84 7.5205   5 3.3633 0.5068 6.5, 22.5 2.45
CC036/Unc f 7.26 5.1743   5 2.314 0.7127 1.3, 14.4 0.5
CC037/TauUnc f 4.62 1.8144   5 0.81142 0.3927 2.2, 7.3 -0.18
CC040/TauUnc f 12.0 6.6693   5 2.9826 0.5558 3.8, 21.9 1.72
CC041/TauUnc f 2.18 0.64576   5 0.28879 0.2962 1.4, 2.9 -0.81
CC045/GeniUnc f 2.55 1.0279   4 0.51397 0.4031 1.2, 3.4 -0.72
CC059/TauUnc f 7.44 5.9324   5 2.653 0.7974 3.3, 17.8 0.54
CC063/Unc f 13.733 7.4795   3 4.3183 0.5446 5.9, 20.8 2.17
CC071/TauUnc f 0.7 0.29155   5 0.13038 0.4165 0.5, 1.2 -1.19


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
CC001/Unc f 2.58 1.5942080028 5.7531916543 -0.5931916543
CC002/Unc f 4.14 1.5942080028 7.3131916543 0.9668083457
CC004/TauUnc f 3.1 1.5942080028 6.2731916543 -0.0731916543
CC006/TauUnc f 4.925 1.7823787322 8.4727361223 1.3772638777
CC008/GeniUnc f 1.425 1.7823787322 4.9727361223 -2.1227361223
CC011/Unc f 2.5 1.5942080028 5.6731916543 -0.6731916543
CC012/GeniUnc f 4.68 1.5942080028 7.8531916543 1.5068083457
CC019/TauUnc f 5.38 1.5942080028 8.5531916543 2.2068083457
CC024/GeniUnc f 4.15 2.5206641764 9.1672565399 -0.8672565399
CC027/GeniUnc f 3.78 1.5942080028 6.9531916543 0.6068083457
CC028/GeniUnc f 1.475 1.7823787322 5.0227361223 -2.0727361223
CC030/GeniUnc f 6.2 1.5942080028 9.3731916543 3.0268083457
CC032/GeniUnc f 7.56 1.5942080028 10.7331916543 4.3868083457
CC035/Unc f 14.84 1.5942080028 18.0131916543 11.6668083457
CC036/Unc f 7.26 1.5942080028 10.4331916543 4.0868083457
CC037/TauUnc f 4.62 1.5942080028 7.7931916543 1.4468083457
CC040/TauUnc f 12.0 1.5942080028 15.1731916543 8.8268083457
CC041/TauUnc f 2.18 1.5942080028 5.3531916543 -0.9931916543
CC045/GeniUnc f 2.55 1.7823787322 6.0977361223 -0.9977361223
CC059/TauUnc f 7.44 1.5942080028 10.6131916543 4.2668083457
CC063/Unc f 13.7333333333 2.0581136817 17.8299061438 9.6367605229
CC071/TauUnc f 0.7 1.5942080028 3.8731916543 -2.4731916543




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA