Project measure / variable:   Bennett4   AST_post_HFHS

ID, description, units MPD:114740   AST_post_HFHS   plasma aspartate aminotransferase (AST) amount, post-diet   [U/L]  HFHS group  
various diets 2 study
Data set, strains Bennett4   CC   22 strains     sex: f     age: 17-20wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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Bennett4 - plasma aspartate aminotransferase (AST) amount, post-diet HFHS group



  MEASURE SUMMARY
Measure Summary Female
Number of strains tested22 strains
Mean of the strain means210.7   U/L
Median of the strain means206.6   U/L
SD of the strain means± 76.03
Coefficient of variation (CV)0.3609
Min–max range of strain means84.24   –   392.5   U/L
Mean sample size per strain4.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 21 471953.5031 22473.9763 1.1061 0.3608
Residuals 76 1544246.1065 20319.0277


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
CC001/Unc f 173.0 98.81   5 44.19 0.5712 89.4, 342.6 -0.5
CC002/Unc f 128.0 50.57   5 22.614 0.395 79.05, 192.3 -1.09
CC004/TauUnc f 166.4 74.6   5 33.363 0.4484 76.8, 266.4 -0.58
CC006/TauUnc f 203.0 97.14   4 48.571 0.4786 122.1, 320.4 -0.1
CC008/GeniUnc f 138.0 53.56   4 26.781 0.3881 66.9, 187.8 -0.96
CC011/Unc f 84.24 30.146   5 13.482 0.3579 56.1, 132.6 -1.66
CC012/GeniUnc f 169.3 46.103   5 20.618 0.2724 108.9, 234.9 -0.54
CC019/TauUnc f 244.1 154.6   5 69.13 0.6333 102.0, 453.0 0.44
CC024/GeniUnc f 392.5 370.2   2   261.7 0.943 130.8, 654.3 2.39
CC027/GeniUnc f 293.8 264.4   5 118.3 0.9 108.9, 743.4 1.09
CC028/GeniUnc f 286.8 284.6   4 142.3 0.9924 109.3, 709.8 1.0
CC030/GeniUnc f 210.2 101.9   5 45.552 0.4846 112.8, 332.1 -0.01
CC032/GeniUnc f 153.5 67.51   5 30.194 0.4398 105.8, 269.4 -0.75
CC035/Unc f 167.3 51.72   5 23.132 0.3091 128.7, 252.6 -0.57
CC036/Unc f 129.2 75.61   5 33.812 0.5854 70.5, 256.5 -1.07
CC037/TauUnc f 260.3 215.0   5 96.13 0.8258 97.5, 593.1 0.65
CC040/TauUnc f 250.1 198.6   4 99.29 0.7942 121.8, 545.7 0.52
CC041/TauUnc f 105.3 27.581   5 12.335 0.262 77.7, 144.9 -1.39
CC045/GeniUnc f 275.6 50.11   4 25.057 0.1818 231.2, 324.6 0.85
CC059/TauUnc f 276.7 197.5   5 88.34 0.7139 113.1, 596.1 0.87
CC063/Unc f 255.9 50.56   3 29.189 0.1976 205.8, 306.9 0.59
CC071/TauUnc f 271.8 223.7   3 129.2 0.8231 100.8, 525.0 0.8


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
CC001/Unc f 172.98 63.7479846224 299.9451148925 46.0148851075
CC002/Unc f 128.03 63.7479846224 254.9951148925 1.0648851075
CC004/TauUnc f 166.36 63.7479846224 293.3251148925 39.3948851075
CC006/TauUnc f 202.95 71.2724135222 344.9013138354 60.9986861646
CC008/GeniUnc f 138.0 71.2724135222 279.9513138354 -3.9513138354
CC011/Unc f 84.24 63.7479846224 211.2051148925 -42.7251148925
CC012/GeniUnc f 169.26 63.7479846224 296.2251148925 42.2948851075
CC019/TauUnc f 244.08 63.7479846224 371.0451148925 117.1148851075
CC024/GeniUnc f 392.55 100.7944138261 593.2994732227 191.8005267773
CC027/GeniUnc f 293.82 63.7479846224 420.7851148925 166.8548851075
CC028/GeniUnc f 286.825 71.2724135222 428.7763138354 144.8736861646
CC030/GeniUnc f 210.18 63.7479846224 337.1451148925 83.2148851075
CC032/GeniUnc f 153.52 63.7479846224 280.4851148925 26.5548851075
CC035/Unc f 167.34 63.7479846224 294.3051148925 40.3748851075
CC036/Unc f 129.16 63.7479846224 256.1251148925 2.1948851075
CC037/TauUnc f 260.28 63.7479846224 387.2451148925 133.3148851075
CC040/TauUnc f 250.05 71.2724135222 392.0013138354 108.0986861646
CC041/TauUnc f 105.28 63.7479846224 232.2451148925 -21.6851148925
CC045/GeniUnc f 275.65 71.2724135222 417.6013138354 133.6986861646
CC059/TauUnc f 276.7 63.7479846224 403.6651148925 149.7348851075
CC063/Unc f 255.9 82.2982942656 419.8112585094 91.9887414906
CC071/TauUnc f 271.8 82.2982942656 435.7112585094 107.8887414906




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA