Project measure / variable:   Bennett4   AST_base_HP

ID, description, units MPD:114737   AST_base_HP   plasma aspartate aminotransferase (AST) amount, baseline   [U/L]  HP group  
various diets 2 study
Data set, strains Bennett4   CC   22 strains     sex: f     age: 8-11wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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Bennett4 - plasma aspartate aminotransferase (AST) amount, baseline HP group



  MEASURE SUMMARY
Measure Summary Female
Number of strains tested22 strains
Mean of the strain means248.0   U/L
Median of the strain means225.8   U/L
SD of the strain means± 98.9
Coefficient of variation (CV)0.3989
Min–max range of strain means117.5   –   497.2   U/L
Mean sample size per strain4.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 21 926456.5471 44116.9784 1.7312 0.0429
Residuals 79 2013149.703 25482.9076


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
CC001/Unc f 354.7 177.1   5 79.19 0.4992 182.7, 612.9 1.08
CC002/Unc f 261.6 202.8   5 90.69 0.7752 107.7, 608.1 0.14
CC004/TauUnc f 392.0 204.8   5 91.57 0.5224 155.4, 653.2 1.46
CC006/TauUnc f 497.2 335.0   4 167.5 0.6738 292.8, 997.8 2.52
CC008/GeniUnc f 196.8 60.25   4 30.123 0.3061 137.1, 278.1 -0.52
CC011/Unc f 117.5 26.047   5 11.649 0.2217 88.8, 158.4 -1.32
CC012/GeniUnc f 223.9 102.3   5 45.736 0.4568 123.9, 371.2 -0.24
CC019/TauUnc f 175.3 106.0   5 47.39 0.6044 86.1, 329.1 -0.73
CC024/GeniUnc f 158.2 39.669   2   28.05 0.2507 130.2, 186.3 -0.91
CC027/GeniUnc f 295.4 150.4   5 67.26 0.5091 118.2, 515.1 0.48
CC028/GeniUnc f 196.1 134.9   4 67.46 0.6881 111.8, 396.8 -0.52
CC030/GeniUnc f 249.0 164.7   5 73.66 0.6615 117.6, 447.0 0.01
CC032/GeniUnc f 163.3 67.63   5 30.246 0.4141 88.2, 230.1 -0.86
CC035/Unc f 189.1 111.4   5 49.818 0.5892 82.8, 378.3 -0.6
CC036/Unc f 147.6 68.39   5 30.586 0.4635 101.1, 266.2 -1.01
CC037/TauUnc f 143.6 44.117   5 19.73 0.3073 97.2, 194.7 -1.06
CC040/TauUnc f 396.4 208.1   5 93.08 0.5251 132.0, 647.7 1.5
CC041/TauUnc f 269.2 92.41   5 41.328 0.3433 207.4, 430.8 0.21
CC045/GeniUnc f 252.0 124.7   4 62.36 0.4949 157.8, 431.4 0.04
CC059/TauUnc f 365.3 319.1   5 142.7 0.8737 130.5, 905.1 1.19
CC063/Unc f 183.2 73.1   3 42.201 0.399 140.4, 267.6 -0.65
CC071/TauUnc f 227.6 155.5   5 69.55 0.6834 71.1, 459.9 -0.21


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
CC001/Unc f 354.74 71.3903461722 496.8389295468 212.6410704532
CC002/Unc f 261.58 71.3903461722 403.6789295468 119.4810704532
CC004/TauUnc f 391.98 71.3903461722 534.0789295468 249.8810704532
CC006/TauUnc f 497.175 79.8168334891 656.0464329983 338.3035670017
CC008/GeniUnc f 196.825 79.8168334891 355.6964329983 37.9535670017
CC011/Unc f 117.48 71.3903461722 259.5789295468 -24.6189295468
CC012/GeniUnc f 223.88 71.3903461722 365.9789295468 81.7810704532
CC019/TauUnc f 175.32 71.3903461722 317.4189295468 33.2210704532
CC024/GeniUnc f 158.25 112.878048426 382.9281352198 -66.4281352198
CC027/GeniUnc f 295.4 71.3903461722 437.4989295468 153.3010704532
CC028/GeniUnc f 196.075 79.8168334891 354.9464329983 37.2035670017
CC030/GeniUnc f 249.02 71.3903461722 391.1189295468 106.9210704532
CC032/GeniUnc f 163.32 71.3903461722 305.4189295468 21.2210704532
CC035/Unc f 189.06 71.3903461722 331.1589295468 46.9610704532
CC036/Unc f 147.56 71.3903461722 289.6589295468 5.4610704532
CC037/TauUnc f 143.58 71.3903461722 285.6789295468 1.4810704532
CC040/TauUnc f 396.4 71.3903461722 538.4989295468 254.3010704532
CC041/TauUnc f 269.22 71.3903461722 411.3189295468 127.1210704532
CC045/GeniUnc f 252.025 79.8168334891 410.8964329983 93.1535670017
CC059/TauUnc f 365.26 71.3903461722 507.3589295468 223.1610704532
CC063/Unc f 183.2 92.1645406016 366.6489292162 -0.2489292162
CC071/TauUnc f 227.58 71.3903461722 369.6789295468 85.4810704532




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA