Project measure / variable:   Bennett4   ALT_base_HFHS

ID, description, units MPD:114734   ALT_base_HFHS   plasma alanine aminotransferase (ALT) amount, baseline   [U/L]  HFHS group  
various diets 2 study
Data set, strains Bennett4   CC   22 strains     sex: f     age: 8-11wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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Bennett4 - plasma alanine aminotransferase (ALT) amount, baseline HFHS group



  MEASURE SUMMARY
Measure Summary Female
Number of strains tested22 strains
Mean of the strain means91.19   U/L
Median of the strain means76.21   U/L
SD of the strain means± 57.3
Coefficient of variation (CV)0.6283
Min–max range of strain means25.81   –   266.9   U/L
Mean sample size per strain4.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 21 284038.6419 13525.6496 2.2488 0.0053
Residuals 79 475153.011 6014.5951


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
CC001/Unc f 108.3 33.104   5 14.805 0.3057 67.5, 153.9 0.3
CC002/Unc f 67.24 34.305   5 15.342 0.5102 20.4, 98.1 -0.42
CC004/TauUnc f 95.04 72.75   5 32.534 0.7655 43.5, 219.6 0.07
CC006/TauUnc f 266.9 225.4   4 112.7 0.8442 46.5, 474.6 3.07
CC008/GeniUnc f 88.66 29.096   4 14.548 0.3282 68.7, 131.9 -0.04
CC011/Unc f 57.45 25.87   5 11.569 0.4503 36.75, 95.7 -0.59
CC012/GeniUnc f 63.36 19.089   5 8.5368 0.3013 42.0, 93.9 -0.49
CC019/TauUnc f 38.52 20.447   5 9.144 0.5308 22.2, 73.65 -0.92
CC024/GeniUnc f 44.775 10.076   2   7.125 0.225 37.65, 51.9 -0.81
CC027/GeniUnc f 68.75 50.15   5 22.429 0.7295 34.8, 151.6 -0.39
CC028/GeniUnc f 88.2 30.533   4 15.267 0.3462 57.3, 126.3 -0.05
CC030/GeniUnc f 25.81 4.0565   5 1.8141 0.1572 21.2, 31.2 -1.14
CC032/GeniUnc f 56.22 34.151   5 15.273 0.6075 29.4, 111.9 -0.61
CC035/Unc f 54.3 20.109   5 8.993 0.3703 26.4, 80.4 -0.64
CC036/Unc f 48.835 13.486   5 6.0313 0.2762 32.7, 67.8 -0.74
CC037/TauUnc f 34.203 11.606   5 5.1902 0.3393 21.0, 45.465 -0.99
CC040/TauUnc f 150.8 134.5   5 60.13 0.8914 21.6, 364.5 1.04
CC041/TauUnc f 125.7 78.65   5 35.175 0.6258 58.95, 261.1 0.6
CC045/GeniUnc f 112.0 16.656   4 8.3281 0.1488 96.0, 131.1 0.36
CC059/TauUnc f 130.9 120.1   5 53.71 0.9177 45.9, 340.2 0.69
CC063/Unc f 196.6 200.7   3 115.9 1.021 55.95, 426.5 1.84
CC071/TauUnc f 83.67 82.84   5 37.047 0.9901 29.1, 228.9 -0.13


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
CC001/Unc f 108.3 34.6831229155 177.3350292986 39.2649707014
CC002/Unc f 67.24 34.6831229155 136.2750292986 -1.7950292986
CC004/TauUnc f 95.04 34.6831229155 164.0750292986 26.0049707014
CC006/TauUnc f 266.925 38.7769102555 344.1085091701 189.7414908299
CC008/GeniUnc f 88.6625 38.7769102555 165.8460091701 11.4789908299
CC011/Unc f 57.45 34.6831229155 126.4850292986 -11.5850292986
CC012/GeniUnc f 63.36 34.6831229155 132.3950292986 -5.6750292986
CC019/TauUnc f 38.52 34.6831229155 107.5550292986 -30.5150292986
CC024/GeniUnc f 44.775 54.8388323903 153.92896546 -64.37896546
CC027/GeniUnc f 68.75 34.6831229155 137.7850292986 -0.2850292986
CC028/GeniUnc f 88.2 38.7769102555 165.3835091701 11.0164908299
CC030/GeniUnc f 25.81 34.6831229155 94.8450292986 -43.2250292986
CC032/GeniUnc f 56.22 34.6831229155 125.2550292986 -12.8150292986
CC035/Unc f 54.3 34.6831229155 123.3350292986 -14.7350292986
CC036/Unc f 48.8348 34.6831229155 117.8698292986 -20.2002292986
CC037/TauUnc f 34.203 34.6831229155 103.2380292986 -34.8320292986
CC040/TauUnc f 150.84 34.6831229155 219.8750292986 81.8049707014
CC041/TauUnc f 125.69 34.6831229155 194.7250292986 56.6549707014
CC045/GeniUnc f 111.95 38.7769102555 189.1335091701 34.7664908299
CC059/TauUnc f 130.86 34.6831229155 199.8950292986 61.8249707014
CC063/Unc f 196.6166666667 44.7757191487 285.7405062594 107.4928270739
CC071/TauUnc f 83.67 34.6831229155 152.7050292986 14.6349707014




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA