Project measure / variable:   Auwerx2   fatty_acids_HFD

ID, description, units MPD:114694   fatty_acids_HFD   plasma free fatty acids amount   [mmol/L]  HFD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 21wks
Procedure lipid profile
Ontology mappings

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  STRAIN COMPARISON PLOT
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Auwerx2 - plasma free fatty acids amount HFD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means1.0426   mmol/L 1.1743   mmol/L
Median of the strain means1.11   mmol/L 1.158   mmol/L
SD of the strain means± 0.24415 ± 0.47027
Coefficient of variation (CV)0.2342 0.4005
Min–max range of strain means0.71   –   1.344   mmol/L 0.585   –   2.218   mmol/L
Mean sample size per strain4.9   mice 3.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.5938 0.5938 2.3486 0.131
strain 7 5.9934 0.8562 3.3865 0.0044
sex:strain 7 2.7739 0.3963 1.5674 0.1643
Residuals 56 14.1583 0.2528


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.806 0.27208   5 0.12168 0.3376 0.53, 1.17 -0.97
129S1/SvImJ m 0.585 0.2192   2   0.155 0.3747 0.43, 0.74 -1.25
A/J f 1.2 0.08679   4 0.0434 0.0723 1.12, 1.28 0.64
A/J m 1.158 0.0712   5 0.03184 0.0615 1.07, 1.25 -0.03
C57BL/6J f 1.11 0.25534   3 0.14742 0.23 0.89, 1.39 0.28
C57BL/6J m 1.385 0.20696   4 0.10348 0.1494 1.15, 1.62 0.45
CAST/EiJ f 1.344 0.23158   5 0.10357 0.1723 1.16, 1.64 1.23
CAST/EiJ m 1.315 0.03536   2   0.025 0.0269 1.29, 1.34 0.3
DBA/2J f 0.744 0.06387   5 0.02857 0.0859 0.67, 0.82 -1.22
DBA/2J m 1.222 0.32089   5 0.14351 0.2626 0.71, 1.55 0.1
NOD/ShiLtJ f 1.294 1.1179   10 0.35351 0.8639 0.5, 3.57 1.03
NOD/ShiLtJ m 2.218 0.37593   5 0.16812 0.1695 1.62, 2.55 2.22
NZO/HlLtJ f 0.958 0.10941   5 0.04893 0.1142 0.82, 1.09 -0.35
NZO/HlLtJ m 0.75 0.0   1   0.0 0.0 0.75, 0.75 -0.9
PWK/PhJ f 1.2175 0.1898   4 0.0949 0.1559 0.94, 1.34 0.72
PWK/PhJ m 0.988 0.13664   5 0.06111 0.1383 0.76, 1.08 -0.4
WSB/EiJ f 0.71 0.38743   3 0.22368 0.5457 0.27, 1.0 -1.36
WSB/EiJ m 0.948 0.37851   5 0.16927 0.3993 0.54, 1.45 -0.48


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.806 0.2248672227 1.2564631769 0.3555368231
129S1/SvImJ m 0.585 0.3555462975 1.2972448205 -0.1272448205
A/J f 1.2 0.251409198 1.7036331425 0.6963668575
A/J m 1.158 0.2248672227 1.6084631769 0.7075368231
C57BL/6J f 1.11 0.2903023362 1.6915454607 0.5284545393
C57BL/6J m 1.385 0.251409198 1.8886331425 0.8813668575
CAST/EiJ f 1.344 0.2248672227 1.7944631769 0.8935368231
CAST/EiJ m 1.315 0.3555462975 2.0272448205 0.6027551795
DBA/2J f 0.744 0.2248672227 1.1944631769 0.2935368231
DBA/2J m 1.222 0.2248672227 1.6724631769 0.7715368231
NOD/ShiLtJ f 1.294 0.1590051381 1.6125255671 0.9754744329
NOD/ShiLtJ m 2.218 0.2248672227 2.6684631769 1.7675368231
PWK/PhJ f 1.2175 0.251409198 1.7211331425 0.7138668575
PWK/PhJ m 0.988 0.2248672227 1.4384631769 0.5375368231
WSB/EiJ f 0.71 0.2903023362 1.2915454607 0.1284545393
WSB/EiJ m 0.948 0.2248672227 1.3984631769 0.4975368231


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.6955 0.2103440262 1.1168697183 0.2741302817
A/J both 1.179 0.168650417 1.5168473827 0.8411526173
C57BL/6J both 1.2475 0.1920169467 1.6321561663 0.8628438337
CAST/EiJ both 1.3295 0.2103440262 1.7508697183 0.9081302817
DBA/2J both 0.983 0.1590051381 1.3015255671 0.6644744329
NOD/ShiLtJ both 1.756 0.1377024889 2.0318512328 1.4801487672
PWK/PhJ both 1.10275 0.168650417 1.4405973827 0.7649026173
WSB/EiJ both 0.829 0.1836033185 1.1968016438 0.4611983562




  GWAS USING LINEAR MIXED MODELS