Project measure / variable:   Auwerx2   ldl_CD

ID, description, units MPD:114689   ldl_CD   plasma LDL amount   [mmol/L]  CD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 21wks
Procedure lipid profile
Ontology mappings

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  STRAIN COMPARISON PLOT
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Auwerx2 - plasma LDL amount CD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means0.15574   mmol/L 0.13311   mmol/L
Median of the strain means0.094   mmol/L 0.064   mmol/L
SD of the strain means± 0.19403 ± 0.225
Coefficient of variation (CV)1.2458 1.6903
Min–max range of strain means0.03333   –   0.6675   mmol/L 0.03   –   0.732   mmol/L
Mean sample size per strain4.4   mice 4.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0021 0.0021 0.3153 0.5765
strain 7 3.1204 0.4458 65.6707 < 0.0001
sex:strain 7 0.0338 0.0048 0.7113 0.6625
Residuals 63 0.4276 0.0068


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.094 0.01517   5 0.00678233 0.1613 0.08, 0.11 -0.32
129S1/SvImJ m 0.064 0.02966   5 0.01327 0.4635 0.03, 0.11 -0.31
A/J f 0.072 0.03033   5 0.01356 0.4213 0.04, 0.12 -0.43
A/J m 0.042 0.01643   5 0.00734847 0.3912 0.03, 0.07 -0.4
C57BL/6J f 0.118 0.01643   5 0.00734847 0.1393 0.1, 0.14 -0.19
C57BL/6J m 0.07 0.00707107   5 0.00316228 0.101 0.06, 0.08 -0.28
CAST/EiJ f 0.08 0.0   1   0.0 0.0 0.08, 0.08 -0.39
CAST/EiJ m 0.03 0.03464   3 0.02 1.1547 0.01, 0.07 -0.46
DBA/2J f 0.094 0.01817   5 0.00812404 0.1933 0.07, 0.12 -0.32
DBA/2J m 0.066 0.01342   5 0.006 0.2033 0.05, 0.08 -0.3
NOD/ShiLtJ f 0.11286 0.04231   7 0.01599 0.3749 0.04, 0.17 -0.22
NOD/ShiLtJ m 0.062 0.03347   5 0.01497 0.5398 0.02, 0.1 -0.32
NZO/HlLtJ f 0.6675 0.07365   4 0.03683 0.1103 0.58, 0.76 2.64
NZO/HlLtJ m 0.732 0.3045   5 0.13618 0.416 0.24, 0.95 2.66
PWK/PhJ f 0.13 0.03464   5 0.01549 0.2665 0.08, 0.16 -0.13
PWK/PhJ m 0.06 0.01732   5 0.00774597 0.2887 0.05, 0.09 -0.32
WSB/EiJ f 0.03333 0.01528   3 0.00881917 0.4583 0.02, 0.05 -0.63
WSB/EiJ m 0.072 0.03962   5 0.01772 0.5503 0.03, 0.13 -0.27


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.094 0.0368456465 0.1676301491 0.0203698509
129S1/SvImJ m 0.064 0.0368456465 0.1376301491 -0.0096301491
A/J f 0.072 0.0368456465 0.1456301491 -0.0016301491
A/J m 0.042 0.0368456465 0.1156301491 -0.0316301491
C57BL/6J f 0.118 0.0368456465 0.1916301491 0.0443698509
C57BL/6J m 0.07 0.0368456465 0.1436301491 -0.0036301491
DBA/2J f 0.094 0.0368456465 0.1676301491 0.0203698509
DBA/2J m 0.066 0.0368456465 0.1396301491 -0.0076301491
NOD/ShiLtJ f 0.1128571429 0.0311402549 0.1750859767 0.050628309
NOD/ShiLtJ m 0.062 0.0368456465 0.1356301491 -0.0116301491
NZO/HlLtJ f 0.6675 0.0411946851 0.7498210093 0.5851789907
NZO/HlLtJ m 0.732 0.0368456465 0.8056301491 0.6583698509
PWK/PhJ f 0.13 0.0368456465 0.2036301491 0.0563698509
PWK/PhJ m 0.06 0.0368456465 0.1336301491 -0.0136301491
WSB/EiJ f 0.0333333333 0.047567525 0.1283894471 -0.0617227805
WSB/EiJ m 0.072 0.0368456465 0.1456301491 -0.0016301491


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.079 0.0260538065 0.1310643778 0.0269356222
A/J both 0.057 0.0260538065 0.1090643778 0.0049356222
C57BL/6J both 0.094 0.0260538065 0.1460643778 0.0419356222
DBA/2J both 0.08 0.0260538065 0.1320643778 0.0279356222
NOD/ShiLtJ both 0.0874285714 0.0241211377 0.1356308188 0.039226324
NZO/HlLtJ both 0.69975 0.0276342348 0.7549726118 0.6445273882
PWK/PhJ both 0.095 0.0260538065 0.1470643778 0.0429356222
WSB/EiJ both 0.0526666667 0.0300843444 0.1127854317 -0.0074520984




  GWAS USING LINEAR MIXED MODELS