Project measure / variable:   Auwerx2   chol_CD

ID, description, units MPD:114685   chol_CD   plasma cholesterol amount   [mmol/L]  CD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 21wks
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  STRAIN COMPARISON PLOT
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Auwerx2 - plasma cholesterol amount CD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means2.4481   mmol/L 3.163   mmol/L
Median of the strain means2.18   mmol/L 2.82   mmol/L
SD of the strain means± 1.2553 ± 1.4609
Coefficient of variation (CV)0.5127 0.4619
Min–max range of strain means1.3   –   5.5   mmol/L 1.4667   –   6.52   mmol/L
Mean sample size per strain4.4   mice 4.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 13.5658 13.5658 51.9394 < 0.0001
strain 7 107.7581 15.394 58.9391 < 0.0001
sex:strain 7 7.1992 1.0285 3.9376 0.0013
Residuals 63 16.4547 0.2612


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 2.9 0.14142   5 0.06325 0.0488 2.7, 3.1 0.36
129S1/SvImJ m 3.98 0.46583   5 0.20833 0.117 3.3, 4.5 0.56
A/J f 1.94 0.18166   5 0.08124 0.0936 1.7, 2.1 -0.4
A/J m 2.24 0.15166   5 0.06782 0.0677 2.0, 2.4 -0.63
C57BL/6J f 2.18 0.14832   5 0.06633 0.068 2.0, 2.4 -0.21
C57BL/6J m 3.32 0.17889   5 0.08 0.0539 3.1, 3.5 0.11
CAST/EiJ f 1.3 0.0   1   0.0 0.0 1.3, 1.3 -0.91
CAST/EiJ m 1.4667 0.37859   3 0.21858 0.2581 1.2, 1.9 -1.16
DBA/2J f 1.52 0.16432   5 0.07348 0.1081 1.4, 1.8 -0.74
DBA/2J m 3.36 0.27019   5 0.12083 0.0804 3.1, 3.8 0.13
NOD/ShiLtJ f 2.3 0.38297   7 0.14475 0.1665 2.0, 3.1 -0.12
NOD/ShiLtJ m 2.82 0.17889   5 0.08 0.0634 2.6, 3.0 -0.23
NZO/HlLtJ f 5.5 0.60553   4 0.30277 0.1101 4.6, 5.9 2.43
NZO/HlLtJ m 6.52 1.6223   5 0.72553 0.2488 4.5, 8.3 2.3
PWK/PhJ f 2.66 0.251   5 0.11225 0.0944 2.4, 2.9 0.17
PWK/PhJ m 2.36 0.21909   5 0.09798 0.0928 2.1, 2.7 -0.55
WSB/EiJ f 1.7333 0.25166   3 0.1453 0.1452 1.5, 2.0 -0.57
WSB/EiJ m 2.4 0.60415   5 0.27019 0.2517 1.6, 3.1 -0.52


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 2.9 0.2285542322 3.3567291883 2.4432708117
129S1/SvImJ m 3.98 0.2285542322 4.4367291883 3.5232708117
A/J f 1.94 0.2285542322 2.3967291883 1.4832708117
A/J m 2.24 0.2285542322 2.6967291883 1.7832708117
C57BL/6J f 2.18 0.2285542322 2.6367291883 1.7232708117
C57BL/6J m 3.32 0.2285542322 3.7767291883 2.8632708117
DBA/2J f 1.52 0.2285542322 1.9767291883 1.0632708117
DBA/2J m 3.36 0.2285542322 3.8167291883 2.9032708117
NOD/ShiLtJ f 2.3 0.1931635817 2.6860066167 1.9139933833
NOD/ShiLtJ m 2.82 0.2285542322 3.2767291883 2.3632708117
NZO/HlLtJ f 5.5 0.2555313998 6.0106387562 4.9893612438
NZO/HlLtJ m 6.52 0.2285542322 6.9767291883 6.0632708117
PWK/PhJ f 2.66 0.2285542322 3.1167291883 2.2032708117
PWK/PhJ m 2.36 0.2285542322 2.8167291883 1.9032708117
WSB/EiJ f 1.7333333333 0.295062245 2.32296818 1.1436984867
WSB/EiJ m 2.4 0.2285542322 2.8567291883 1.9432708117


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 3.44 0.1616122474 3.7629563062 3.1170436938
A/J both 2.09 0.1616122474 2.4129563062 1.7670436938
C57BL/6J both 2.75 0.1616122474 3.0729563062 2.4270436938
DBA/2J both 2.44 0.1616122474 2.7629563062 2.1170436938
NOD/ShiLtJ both 2.56 0.149623867 2.8589994396 2.2610005604
NZO/HlLtJ both 6.01 0.1714156741 6.3525468912 5.6674531088
PWK/PhJ both 2.51 0.1616122474 2.8329563062 2.1870436938
WSB/EiJ both 2.0666666667 0.1866137491 2.4395844873 1.693748846




  GWAS USING LINEAR MIXED MODELS