Project measure / variable:   Auwerx2   urea_CD

ID, description, units MPD:114683   urea_CD   plasma urea nitrogen amount   [mmol/L]  CD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 21wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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Auwerx2 - plasma urea nitrogen amount CD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means9.2218   mmol/L 8.7584   mmol/L
Median of the strain means8.992   mmol/L 8.73   mmol/L
SD of the strain means± 2.6457 ± 1.602
Coefficient of variation (CV)0.2869 0.1829
Min–max range of strain means6.33   –   13.278   mmol/L 6.6733   –   11.342   mmol/L
Mean sample size per strain4.4   mice 4.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 11.1296 11.1296 1.1133 0.2954
strain 7 256.3587 36.6227 3.6635 0.0022
sex:strain 7 65.7691 9.3956 0.9399 0.4826
Residuals 63 629.788 9.9966


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 8.992 1.2265   5 0.54852 0.1364 6.82, 9.79 -0.09
129S1/SvImJ m 11.342 2.2161   5 0.99108 0.1954 9.98, 15.2 1.61
A/J f 7.534 0.1997   5 0.08931 0.0265 7.28, 7.77 -0.64
A/J m 8.008 1.3315   5 0.59544 0.1663 6.27, 9.76 -0.47
C57BL/6J f 13.278 1.1903   5 0.53233 0.0896 11.53, 14.77 1.53
C57BL/6J m 10.876 1.8698   5 0.83621 0.1719 8.38, 13.11 1.32
CAST/EiJ f 6.33 0.0   1   0.0 0.0 6.33, 6.33 -1.09
CAST/EiJ m 6.6733 1.7727   3 1.0235 0.2656 5.32, 8.68 -1.3
DBA/2J f 6.636 1.2902   5 0.57698 0.1944 5.56, 8.05 -0.98
DBA/2J m 7.114 0.89083   5 0.39839 0.1252 6.12, 8.24 -1.03
NOD/ShiLtJ f 12.904 9.0958   7 3.4379 0.7049 8.35, 33.44 1.39
NOD/ShiLtJ m 9.57 1.6742   5 0.74874 0.1749 7.25, 11.34 0.51
NZO/HlLtJ f 6.845 0.87119   4 0.43559 0.1273 6.29, 8.13 -0.9
NZO/HlLtJ m 7.712 1.4021   5 0.62702 0.1818 5.89, 9.46 -0.65
PWK/PhJ f 9.84 2.6896   5 1.2028 0.2733 7.04, 13.32 0.23
PWK/PhJ m 8.73 0.92431   5 0.41336 0.1059 7.54, 10.13 -0.02
WSB/EiJ f 10.637 0.34122   3 0.19701 0.0321 10.42, 11.03 0.53
WSB/EiJ m 8.8 2.0648   5 0.92341 0.2346 7.3, 12.27 0.03


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 8.992 1.4139756156 11.8176047988 6.1663952012
129S1/SvImJ m 11.342 1.4139756156 14.1676047988 8.5163952012
A/J f 7.534 1.4139756156 10.3596047988 4.7083952012
A/J m 8.008 1.4139756156 10.8336047988 5.1823952012
C57BL/6J f 13.278 1.4139756156 16.1036047988 10.4523952012
C57BL/6J m 10.876 1.4139756156 13.7016047988 8.0503952012
DBA/2J f 6.636 1.4139756156 9.4616047988 3.8103952012
DBA/2J m 7.114 1.4139756156 9.9396047988 4.2883952012
NOD/ShiLtJ f 12.9042857143 1.1950275076 15.2923576322 10.5162137964
NOD/ShiLtJ m 9.57 1.4139756156 12.3956047988 6.7443952012
NZO/HlLtJ f 6.845 1.5808727975 10.0041222039 3.6858777961
NZO/HlLtJ m 7.712 1.4139756156 10.5376047988 4.8863952012
PWK/PhJ f 9.84 1.4139756156 12.6656047988 7.0143952012
PWK/PhJ m 8.73 1.4139756156 11.5556047988 5.9043952012
WSB/EiJ f 10.6366666667 1.8254346704 14.2845067763 6.9888265571
WSB/EiJ m 8.8 1.4139756156 11.6256047988 5.9743952012


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 10.167 0.9998317462 12.1650043142 8.1689956858
A/J both 7.771 0.9998317462 9.7690043142 5.7729956858
C57BL/6J both 12.077 0.9998317462 14.0750043142 10.0789956858
DBA/2J both 6.875 0.9998317462 8.8730043142 4.8769956858
NOD/ShiLtJ both 11.2371428571 0.9256643271 13.0869354107 9.3873503036
NZO/HlLtJ both 7.2785 1.0604817117 9.3977035991 5.1592964009
PWK/PhJ both 9.285 0.9998317462 11.2830043142 7.2869956858
WSB/EiJ both 9.7183333333 1.1545062557 12.0254299906 7.411236676




  GWAS USING LINEAR MIXED MODELS