Project measure / variable:   Auwerx2   LDH_CD

ID, description, units MPD:114679   LDH_CD   plasma lactate dehydrogenase amount (LDH)   [U/L]  CD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 21wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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Auwerx2 - plasma lactate dehydrogenase amount (LDH) CD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means312.4   U/L 261.5   U/L
Median of the strain means269.8   U/L 262.0   U/L
SD of the strain means± 171.4 ± 83.52
Coefficient of variation (CV)0.5484 0.3194
Min–max range of strain means122.0   –   624.2   U/L 143.8   –   430.0   U/L
Mean sample size per strain4.3   mice 4.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 96700.7547 96700.7547 2.1326 0.1492
strain 7 441249.6329 63035.6618 1.3902 0.2255
sex:strain 7 402042.8199 57434.6886 1.2667 0.2816
Residuals 62 2811311.6643 45343.7365


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 269.8 86.45   5 38.663 0.3204 182.0, 398.0 -0.25
129S1/SvImJ m 262.0 296.2   5 132.5 1.1306 98.0, 790.0 0.01
A/J f 333.8 107.6   5 48.104 0.3222 226.0, 484.0 0.12
A/J m 281.4 167.6   5 74.95 0.5956 147.0, 564.0 0.24
C57BL/6J f 170.8 39.06   5 17.468 0.2287 118.0, 226.0 -0.83
C57BL/6J m 192.4 78.86   5 35.266 0.4099 120.0, 323.0 -0.83
CAST/EiJ f 122.0 0.0   1   0.0 0.0 122.0, 122.0 -1.11
CAST/EiJ m 430.0 335.2   3 193.5 0.7794 235.0, 817.0 2.02
DBA/2J f 198.2 51.83   5 23.178 0.2615 154.0, 286.0 -0.67
DBA/2J m 214.2 98.74   5 44.157 0.461 126.0, 326.0 -0.57
NOD/ShiLtJ f 321.4 102.7   7 38.825 0.3196 186.0, 441.0 0.05
NOD/ShiLtJ m 216.6 16.95   5 7.5802 0.0783 195.0, 233.0 -0.54
NZO/HlLtJ f 624.2 786.8   4 393.4 1.2604 119.0, 1794.0 1.82
NZO/HlLtJ m 313.0 52.41   5 23.437 0.1674 235.0, 359.0 0.62
PWK/PhJ f 219.8 70.02   5 31.314 0.3186 164.0, 337.0 -0.54
PWK/PhJ m 300.0 196.8   5 87.99 0.6558 159.0, 619.0 0.46
WSB/EiJ f 552.0 234.8   2   166.0 0.4253 386.0, 718.0 1.4
WSB/EiJ m 143.8 84.97   5 37.998 0.5909 47.0, 245.0 -1.41


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 269.8 95.2299706193 460.1619988359 79.4380011641
129S1/SvImJ m 262.0 95.2299706193 452.3619988359 71.6380011641
A/J f 333.8 95.2299706193 524.1619988359 143.4380011641
A/J m 281.4 95.2299706193 471.7619988359 91.0380011641
C57BL/6J f 170.8 95.2299706193 361.1619988359 -19.5619988359
C57BL/6J m 192.4 95.2299706193 382.7619988359 2.0380011641
DBA/2J f 198.2 95.2299706193 388.5619988359 7.8380011641
DBA/2J m 214.2 95.2299706193 404.5619988359 23.8380011641
NOD/ShiLtJ f 321.4285714286 80.4840148465 482.3138246833 160.5433181738
NOD/ShiLtJ m 216.6 95.2299706193 406.9619988359 26.2380011641
NZO/HlLtJ f 624.25 106.4703439 837.0811848648 411.4188151352
NZO/HlLtJ m 313.0 95.2299706193 503.3619988359 122.6380011641
PWK/PhJ f 219.8 95.2299706193 410.1619988359 29.4380011641
PWK/PhJ m 300.0 95.2299706193 490.3619988359 109.6380011641
WSB/EiJ f 552.0 150.5718043339 852.9887481318 251.0112518682
WSB/EiJ m 143.8 95.2299706193 334.1619988359 -46.5619988359


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 265.9 67.3377579971 400.5062602571 131.2937397429
A/J both 307.6 67.3377579971 442.2062602571 172.9937397429
C57BL/6J both 181.6 67.3377579971 316.2062602571 46.9937397429
DBA/2J both 206.2 67.3377579971 340.8062602571 71.5937397429
NOD/ShiLtJ both 269.0142857143 62.3426498273 393.6354670155 144.3931044131
NZO/HlLtJ both 468.625 71.4224779645 611.3964991269 325.8535008731
PWK/PhJ both 259.9 67.3377579971 394.5062602571 125.2937397429
WSB/EiJ both 347.9 89.0794807525 525.9673447763 169.8326552237




  GWAS USING LINEAR MIXED MODELS