Project measure / variable:   Auwerx2   eWAT_HFD

ID, description, units MPD:114666   eWAT_HFD   gonadal fat pad weight   [g]  HFD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 21wks
Procedure organ weights
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  STRAIN COMPARISON PLOT
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Auwerx2 - gonadal fat pad weight HFD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means1.9308   g 1.826   g
Median of the strain means0.9533   g 1.3822   g
SD of the strain means± 2.6998 ± 1.708
Coefficient of variation (CV)1.3983 0.9354
Min–max range of strain means0.05393   –   8.6491   g 0.09202   –   5.8722   g
Mean sample size per strain4.4   mice 3.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.4388 0.4388 2.3635 0.1303
strain 7 38.5454 5.5065 29.6599 < 0.0001
sex:strain 7 15.7855 2.2551 12.1466 < 0.0001
Residuals 52 9.654 0.1857


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.63244 0.18019   5 0.08058 0.2849 0.4771, 0.917 -0.48
129S1/SvImJ m 1.7851 0.20697   2   0.14635 0.1159 1.6387, 1.9314 -0.02
A/J f 0.804 0.34726   4 0.17363 0.4319 0.4286, 1.2557 -0.42
A/J m 1.1958 0.34974   5 0.15641 0.2925 0.8198, 1.6502 -0.37
C57BL/6J f 1.3534 0.89445   3 0.51641 0.6609 0.6055, 2.3442 -0.21
C57BL/6J m 2.7778 0.2262   4 0.1131 0.0814 2.4818, 2.9669 0.56
CAST/EiJ f 0.05878 0.01747   5 0.00781399 0.2973 0.0334, 0.0814 -0.69
CAST/EiJ m 0.3429 0.18144   2   0.1283 0.5291 0.2146, 0.4712 -0.87
DBA/2J f 3.2712 0.82313   5 0.36812 0.2516 2.3025, 4.2992 0.5
DBA/2J m 1.3822 0.24344   5 0.10887 0.1761 0.9892, 1.6563 -0.26
NOD/ShiLtJ f 1.6007 0.72894   6 0.29759 0.4554 1.1634, 3.0666 -0.12
NOD/ShiLtJ m 1.3565 0.16433   5 0.07349 0.1211 1.2531, 1.6468 -0.27
NZO/HlLtJ f 8.6491 0.42716   5 0.19103 0.0494 8.2838, 9.2392 2.49
NZO/HlLtJ m 5.8722 0.0   1   0.0 0.0 5.8722, 5.8722 2.37
PWK/PhJ f 0.9533 0.16944   4 0.08472 0.1777 0.7288, 1.1116 -0.36
PWK/PhJ m 1.6296 0.51001   5 0.22808 0.313 1.1213, 2.3344 -0.11
WSB/EiJ f 0.05393 0.03225   3 0.01862 0.598 0.0207, 0.0851 -0.7
WSB/EiJ m 0.09202 0.02161   5 0.00966651 0.2349 0.0709, 0.1201 -1.02


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.63244 0.1926937118 1.0191082211 0.2457717789
129S1/SvImJ m 1.78505 0.30467551 2.3964261387 1.1736738613
A/J f 0.804 0.2154381192 1.2363082136 0.3716917864
A/J m 1.19576 0.1926937118 1.5824282211 0.8090917789
C57BL/6J f 1.3533666667 0.2487665122 1.8525531936 0.8541801397
C57BL/6J m 2.777775 0.2154381192 3.2100832136 2.3454667864
CAST/EiJ f 0.05878 0.1926937118 0.4454482211 -0.3278882211
CAST/EiJ m 0.3429 0.30467551 0.9542761387 -0.2684761387
DBA/2J f 3.27122 0.1926937118 3.6578882211 2.8845517789
DBA/2J m 1.38224 0.1926937118 1.7689082211 0.9955717789
NOD/ShiLtJ f 1.6007 0.1759044877 1.9536781783 1.2477218217
NOD/ShiLtJ m 1.35654 0.1926937118 1.7432082211 0.9698717789
PWK/PhJ f 0.9533 0.2154381192 1.3856082136 0.5209917864
PWK/PhJ m 1.62958 0.1926937118 2.0162482211 1.2429117789
WSB/EiJ f 0.0539333333 0.2487665122 0.5531198603 -0.4452531936
WSB/EiJ m 0.09202 0.1926937118 0.4786882211 -0.2946482211


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 1.208745 0.1802484625 1.5704400014 0.8470499986
A/J both 0.99988 0.1445202838 1.2898811658 0.7098788342
C57BL/6J both 2.0655708333 0.1645435815 2.3957516854 1.7353899813
CAST/EiJ both 0.20084 0.1802484625 0.5625350014 -0.1608550014
DBA/2J both 2.32673 0.1362550303 2.6001457212 2.0533142788
NOD/ShiLtJ both 1.47862 0.1304542596 1.7403956232 1.2168443768
PWK/PhJ both 1.29144 0.1445202838 1.5814411658 1.0014388342
WSB/EiJ both 0.0729766667 0.1573337568 0.3886899472 -0.2427366138




  GWAS USING LINEAR MIXED MODELS