Project measure / variable:   Auwerx2   spleen_wt_HFD

ID, description, units MPD:114664   spleen_wt_HFD   spleen weight   [g]  HFD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 21wks
Procedure organ weights
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  STRAIN COMPARISON PLOT
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Auwerx2 - spleen weight HFD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means0.08014   g 0.05804   g
Median of the strain means0.0751   g 0.0497   g
SD of the strain means± 0.04741 ± 0.02657
Coefficient of variation (CV)0.5917 0.4578
Min–max range of strain means0.01727   –   0.16382   g 0.0192   –   0.09396   g
Mean sample size per strain4.4   mice 3.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0031 0.0031 16.6764 0.0002
strain 7 0.0493 0.007 38.1611 < 0.0001
sex:strain 7 0.0115 0.0016 8.9378 < 0.0001
Residuals 52 0.0096 0.0002


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.05626 0.00505994   5 0.00226287 0.0899 0.0488, 0.0619 -0.5
129S1/SvImJ m 0.0497 0.01174   2   0.0083 0.2362 0.0414, 0.058 -0.31
A/J f 0.06265 0.00443959   4 0.0022198 0.0709 0.0566, 0.0671 -0.37
A/J m 0.04958 0.00360652   5 0.00161289 0.0727 0.0461, 0.0542 -0.32
C57BL/6J f 0.09183 0.01085   3 0.00626534 0.1182 0.0811, 0.1028 0.25
C57BL/6J m 0.08595 0.00702116   4 0.00351058 0.0817 0.0774, 0.0929 1.05
CAST/EiJ f 0.02418 0.00320578   5 0.00143367 0.1326 0.0212, 0.0283 -1.18
CAST/EiJ m 0.02655 0.00601041   2   0.00425 0.2264 0.0223, 0.0308 -1.19
DBA/2J f 0.10056 0.00885257   5 0.00395899 0.088 0.0923, 0.1133 0.43
DBA/2J m 0.09396 0.01194   5 0.00534178 0.1271 0.0787, 0.106 1.35
NOD/ShiLtJ f 0.0751 0.00966933   6 0.00394749 0.1288 0.0622, 0.087 -0.11
NOD/ShiLtJ m 0.0645 0.00530707   5 0.00237339 0.0823 0.0572, 0.0703 0.24
NZO/HlLtJ f 0.16382 0.02103   5 0.00940396 0.1284 0.132, 0.1854 1.76
NZO/HlLtJ m 0.0859 0.0   1   0.0 0.0 0.0859, 0.0859 1.05
PWK/PhJ f 0.12957 0.04783   4 0.02392 0.3691 0.1021, 0.2012 1.04
PWK/PhJ m 0.04704 0.00953247   5 0.00426305 0.2026 0.0336, 0.0554 -0.41
WSB/EiJ f 0.01727 0.00493592   3 0.00284976 0.2859 0.0137, 0.0229 -1.33
WSB/EiJ m 0.0192 0.00297825   5 0.00133192 0.1551 0.0171, 0.0243 -1.46


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.05626 0.0060724883 0.0684453393 0.0440746607
129S1/SvImJ m 0.0497 0.0096014471 0.0689667132 0.0304332868
A/J f 0.06265 0.0067892484 0.0762736236 0.0490263764
A/J m 0.04958 0.0060724883 0.0617653393 0.0373946607
C57BL/6J f 0.0918333333 0.0078395487 0.1075645388 0.0761021279
C57BL/6J m 0.08595 0.0067892484 0.0995736236 0.0723263764
CAST/EiJ f 0.02418 0.0060724883 0.0363653393 0.0119946607
CAST/EiJ m 0.02655 0.0096014471 0.0458167132 0.0072832868
DBA/2J f 0.10056 0.0060724883 0.1127453393 0.0883746607
DBA/2J m 0.09396 0.0060724883 0.1061453393 0.0817746607
NOD/ShiLtJ f 0.0751 0.0055433981 0.086223642 0.063976358
NOD/ShiLtJ m 0.0645 0.0060724883 0.0766853393 0.0523146607
PWK/PhJ f 0.129575 0.0067892484 0.1431986236 0.1159513764
PWK/PhJ m 0.04704 0.0060724883 0.0592253393 0.0348546607
WSB/EiJ f 0.0172666667 0.0078395487 0.0329978721 0.0015354612
WSB/EiJ m 0.0192 0.0060724883 0.0313853393 0.0070146607


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.05298 0.0056802927 0.0643783412 0.0415816588
A/J both 0.056115 0.0045543663 0.0652540045 0.0469759955
C57BL/6J both 0.0888916667 0.0051853741 0.099296881 0.0784864523
CAST/EiJ both 0.025365 0.0056802927 0.0367633412 0.0139666588
DBA/2J both 0.09726 0.0042938977 0.1058763361 0.0886436639
NOD/ShiLtJ both 0.0698 0.004111094 0.0780495137 0.0615504863
PWK/PhJ both 0.0883075 0.0045543663 0.0974465045 0.0791684955
WSB/EiJ both 0.0182333333 0.004958166 0.0281826212 0.0082840454




  GWAS USING LINEAR MIXED MODELS