Project measure / variable:   Auwerx2   liver_wt_HFD

ID, description, units MPD:114662   liver_wt_HFD   liver weight   [g]  HFD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 21wks
Procedure organ weights
Ontology mappings

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  STRAIN COMPARISON PLOT
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Auwerx2 - liver weight HFD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means1.2096   g 1.2971   g
Median of the strain means0.95297   g 1.0029   g
SD of the strain means± 0.96186 ± 0.84378
Coefficient of variation (CV)0.7952 0.6505
Min–max range of strain means0.3632   –   3.5971   g 0.48618   –   3.1736   g
Mean sample size per strain4.3   mice 3.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.2984 0.2984 5.3901 0.0243
strain 7 9.4375 1.3482 24.3533 < 0.0001
sex:strain 7 2.2584 0.3226 5.8279 < 0.0001
Residuals 51 2.8234 0.0554


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.86822 0.15253   5 0.06821 0.1757 0.6891, 1.0292 -0.35
129S1/SvImJ m 1.0029 0.06364   2   0.045 0.0635 0.9579, 1.0479 -0.35
A/J f 0.94738 0.17384   4 0.08692 0.1835 0.7697, 1.184 -0.27
A/J m 0.75724 0.04689   5 0.02097 0.0619 0.695, 0.8108 -0.64
C57BL/6J f 0.95297 0.12383   3 0.07149 0.1299 0.826, 1.0734 -0.27
C57BL/6J m 1.6625 0.42606   4 0.21303 0.2563 1.0838, 2.0278 0.43
CAST/EiJ f 0.41922 0.05933   5 0.02653 0.1415 0.3621, 0.5049 -0.82
CAST/EiJ m 0.63805 0.00982878   2   0.00695 0.0154 0.6311, 0.645 -0.78
DBA/2J f 1.5098 0.36082   5 0.16136 0.239 1.0401, 1.912 0.31
DBA/2J m 1.4925 0.16746   5 0.07489 0.1122 1.3782, 1.7826 0.23
NOD/ShiLtJ f 1.0945 0.22592   6 0.09223 0.2064 0.8923, 1.4997 -0.12
NOD/ShiLtJ m 1.7422 0.34069   5 0.15236 0.1956 1.2819, 2.075 0.53
NZO/HlLtJ f 3.5971 0.61383   5 0.27451 0.1706 2.6365, 4.2773 2.48
NZO/HlLtJ m 3.1736 0.0   1   0.0 0.0 3.1736, 3.1736 2.22
PWK/PhJ f 1.1344 0.13999   4 0.07 0.1234 0.9285, 1.2418 -0.08
PWK/PhJ m 0.71858 0.36268   5 0.1622 0.5047 0.1405, 1.1393 -0.69
WSB/EiJ f 0.3632 0.08683   2   0.0614 0.2391 0.3018, 0.4246 -0.88
WSB/EiJ m 0.48618 0.15208   5 0.06801 0.3128 0.2412, 0.6213 -0.96


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.86822 0.1052239879 1.0794659704 0.6569740296
129S1/SvImJ m 1.0029 0.1663737332 1.3369092065 0.6688907935
A/J f 0.947375 0.1176439949 1.1835551749 0.7111948251
A/J m 0.75724 0.1052239879 0.9684859704 0.5459940296
C57BL/6J f 0.9529666667 0.1358435843 1.2256840418 0.6802492915
C57BL/6J m 1.6625 0.1176439949 1.8986801749 1.4263198251
CAST/EiJ f 0.41922 0.1052239879 0.6304659704 0.2079740296
CAST/EiJ m 0.63805 0.1663737332 0.9720592065 0.3040407935
DBA/2J f 1.50978 0.1052239879 1.7210259704 1.2985340296
DBA/2J m 1.49254 0.1052239879 1.7037859704 1.2812940296
NOD/ShiLtJ f 1.0944833333 0.0960559196 1.2873236386 0.901643028
NOD/ShiLtJ m 1.74218 0.1052239879 1.9534259704 1.5309340296
PWK/PhJ f 1.134375 0.1176439949 1.3705551749 0.8981948251
PWK/PhJ m 0.71858 0.1052239879 0.9298259704 0.5073340296
WSB/EiJ f 0.3632 0.1663737332 0.6972092065 0.0291907935
WSB/EiJ m 0.48618 0.1052239879 0.6974259704 0.2749340296


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.93556 0.0984280279 1.1331625114 0.7379574886
A/J both 0.8523075 0.0789179909 1.0107419778 0.6938730222
C57BL/6J both 1.3077333333 0.0898520853 1.4881189215 1.1273477451
CAST/EiJ both 0.528635 0.0984280279 0.7262375114 0.3310324886
DBA/2J both 1.50116 0.0744045954 1.6505334582 1.3517865418
NOD/ShiLtJ both 1.4183316667 0.0712369766 1.5613458647 1.2753174686
PWK/PhJ both 0.9264775 0.0789179909 1.0849119778 0.7680430222
WSB/EiJ both 0.42469 0.0984280279 0.6222925114 0.2270874886




  GWAS USING LINEAR MIXED MODELS