Project measure / variable:   Auwerx2   liver_wt_CD

ID, description, units MPD:114661   liver_wt_CD   liver weight   [g]  CD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 21wks
Procedure organ weights
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  STRAIN COMPARISON PLOT
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Auwerx2 - liver weight CD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means0.98103   g 1.1298   g
Median of the strain means0.90844   g 1.0679   g
SD of the strain means± 0.53616 ± 0.58819
Coefficient of variation (CV)0.5465 0.5206
Min–max range of strain means0.4532   –   2.2461   g 0.44797   –   2.3225   g
Mean sample size per strain4.4   mice 4.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.5509 0.5509 10.3467 0.002
strain 7 18.4651 2.6379 49.5401 < 0.0001
sex:strain 7 0.5612 0.0802 1.5057 0.1817
Residuals 63 3.3546 0.0532


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.7125 0.05894   5 0.02636 0.0827 0.649, 0.7799 -0.5
129S1/SvImJ m 0.7857 0.1516   5 0.0678 0.1929 0.6675, 1.0491 -0.59
A/J f 0.96388 0.20717   5 0.09265 0.2149 0.7112, 1.2366 -0.03
A/J m 0.86828 0.12356   5 0.05526 0.1423 0.79, 1.086 -0.44
C57BL/6J f 0.83234 0.05975   5 0.02672 0.0718 0.7625, 0.9154 -0.28
C57BL/6J m 1.1499 0.15912   5 0.07116 0.1384 0.9324, 1.3817 0.03
CAST/EiJ f 0.4532 0.0   1   0.0 0.0 0.4532, 0.4532 -0.98
CAST/EiJ m 0.44797 0.1978   3 0.1142 0.4416 0.2212, 0.585 -1.16
DBA/2J f 1.1769 0.15598   5 0.06976 0.1325 1.0478, 1.4287 0.37
DBA/2J m 1.6577 0.27852   5 0.12456 0.168 1.1996, 1.9166 0.9
NOD/ShiLtJ f 1.0776 0.23649   7 0.08939 0.2195 0.746, 1.4265 0.18
NOD/ShiLtJ m 1.3429 0.25413   5 0.11365 0.1892 1.0685, 1.6132 0.36
NZO/HlLtJ f 2.2461 0.62763   4 0.31381 0.2794 1.4644, 2.878 2.36
NZO/HlLtJ m 2.3225 0.23699   5 0.10599 0.102 2.166, 2.7171 2.03
PWK/PhJ f 0.90844 0.24632   5 0.11016 0.2711 0.6735, 1.2404 -0.14
PWK/PhJ m 1.0679 0.18834   5 0.08423 0.1764 0.9555, 1.4019 -0.11
WSB/EiJ f 0.45827 0.14059   3 0.08117 0.3068 0.3722, 0.6205 -0.97
WSB/EiJ m 0.52552 0.13079   5 0.05849 0.2489 0.3718, 0.7317 -1.03


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.7125 0.1031960429 0.9187208364 0.5062791636
129S1/SvImJ m 0.7857 0.1031960429 0.9919208364 0.5794791636
A/J f 0.96388 0.1031960429 1.1701008364 0.7576591636
A/J m 0.86828 0.1031960429 1.0745008364 0.6620591636
C57BL/6J f 0.83234 0.1031960429 1.0385608364 0.6261191636
C57BL/6J m 1.14988 0.1031960429 1.3561008364 0.9436591636
DBA/2J f 1.17694 0.1031960429 1.3831608364 0.9707191636
DBA/2J m 1.6577 0.1031960429 1.8639208364 1.4514791636
NOD/ShiLtJ f 1.0776142857 0.0872165747 1.251902703 0.9033258684
NOD/ShiLtJ m 1.34292 0.1031960429 1.5491408364 1.1366991636
NZO/HlLtJ f 2.2461 0.1153766835 2.4766619043 2.0155380957
NZO/HlLtJ m 2.32254 0.1031960429 2.5287608364 2.1163191636
PWK/PhJ f 0.90844 0.1031960429 1.1146608364 0.7022191636
PWK/PhJ m 1.06792 0.1031960429 1.2741408364 0.8616991636
WSB/EiJ f 0.4582666667 0.1332255185 0.7244966217 0.1920367117
WSB/EiJ m 0.52552 0.1031960429 0.7317408364 0.3192991636


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.7491 0.0729706217 0.8949201518 0.6032798482
A/J both 0.91608 0.0729706217 1.0619001518 0.7702598482
C57BL/6J both 0.99111 0.0729706217 1.1369301518 0.8452898482
DBA/2J both 1.41732 0.0729706217 1.5631401518 1.2714998482
NOD/ShiLtJ both 1.2102671429 0.0675576683 1.3452703704 1.0752639153
NZO/HlLtJ both 2.28432 0.0773970322 2.4389856273 2.1296543727
PWK/PhJ both 0.98818 0.0729706217 1.1340001518 0.8423598482
WSB/EiJ both 0.4918933333 0.0842592162 0.6602719412 0.3235147255




  GWAS USING LINEAR MIXED MODELS