Project measure / variable:   Auwerx2   heart_wt_HFD

ID, description, units MPD:114656   heart_wt_HFD   heart weight   [g]  HFD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 21wks
Procedure organ weights
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  STRAIN COMPARISON PLOT
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Auwerx2 - heart weight HFD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means0.12812   g 0.14712   g
Median of the strain means0.11832   g 0.1246   g
SD of the strain means± 0.04604 ± 0.05126
Coefficient of variation (CV)0.3594 0.3484
Min–max range of strain means0.07856   –   0.23474   g 0.09572   –   0.2438   g
Mean sample size per strain4.4   mice 3.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0085 0.0085 55.7097 < 0.0001
strain 7 0.0577 0.0082 54.2916 < 0.0001
sex:strain 7 0.0087 0.0012 8.1932 < 0.0001
Residuals 52 0.0079 0.0002


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.11832 0.0116   5 0.00518733 0.098 0.1095, 0.1385 -0.21
129S1/SvImJ m 0.1246 0.0164   2   0.0116 0.1317 0.113, 0.1362 -0.44
A/J f 0.10995 0.01836   4 0.00917901 0.167 0.09, 0.1344 -0.39
A/J m 0.10682 0.00634366   5 0.00283697 0.0594 0.0994, 0.1156 -0.79
C57BL/6J f 0.12747 0.01025   3 0.00591674 0.0804 0.1161, 0.136 -0.01
C57BL/6J m 0.16795 0.00586828   4 0.00293414 0.0349 0.1614, 0.175 0.41
CAST/EiJ f 0.07856 0.00346309   5 0.00154874 0.0441 0.075, 0.0829 -1.08
CAST/EiJ m 0.10505 0.00898026   2   0.00635 0.0855 0.0987, 0.1114 -0.82
DBA/2J f 0.1512 0.01147   5 0.00512757 0.0758 0.134, 0.1634 0.5
DBA/2J m 0.21166 0.01594   5 0.00712668 0.0753 0.1878, 0.2258 1.26
NOD/ShiLtJ f 0.11457 0.01214   6 0.00495706 0.106 0.0956, 0.1276 -0.29
NOD/ShiLtJ m 0.14428 0.01244   5 0.00556394 0.0862 0.1304, 0.1567 -0.06
NZO/HlLtJ f 0.23474 0.01813   5 0.00810615 0.0772 0.2114, 0.2559 2.32
NZO/HlLtJ m 0.2438 0.0   1   0.0 0.0 0.2438, 0.2438 1.89
PWK/PhJ f 0.1343 0.00738512   4 0.00369256 0.055 0.1259, 0.1408 0.13
PWK/PhJ m 0.1242 0.02343   5 0.01048 0.1886 0.088, 0.1513 -0.45
WSB/EiJ f 0.08393 0.0042004   3 0.0024251 0.05 0.0797, 0.0881 -0.96
WSB/EiJ m 0.09572 0.00668596   5 0.00299005 0.0698 0.0887, 0.1031 -1.0


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.11832 0.0055096865 0.1293759947 0.1072640053
129S1/SvImJ m 0.1246 0.0087115792 0.1420810626 0.1071189374
A/J f 0.10995 0.0061600167 0.1223109779 0.0975890221
A/J m 0.10682 0.0055096865 0.1178759947 0.0957640053
C57BL/6J f 0.1274666667 0.0071129746 0.1417398945 0.1131934388
C57BL/6J m 0.16795 0.0061600167 0.1803109779 0.1555890221
CAST/EiJ f 0.07856 0.0055096865 0.0896159947 0.0675040053
CAST/EiJ m 0.10505 0.0087115792 0.1225310626 0.0875689374
DBA/2J f 0.1512 0.0055096865 0.1622559947 0.1401440053
DBA/2J m 0.21166 0.0055096865 0.2227159947 0.2006040053
NOD/ShiLtJ f 0.1145666667 0.0050296326 0.1246593628 0.1044739705
NOD/ShiLtJ m 0.14428 0.0055096865 0.1553359947 0.1332240053
PWK/PhJ f 0.1343 0.0061600167 0.1466609779 0.1219390221
PWK/PhJ m 0.1242 0.0055096865 0.1352559947 0.1131440053
WSB/EiJ f 0.0839333333 0.0071129746 0.0982065612 0.0696601055
WSB/EiJ m 0.09572 0.0055096865 0.1067759947 0.0846640053


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.12146 0.0051538398 0.1318019361 0.1111180639
A/J both 0.108385 0.0041322648 0.116676996 0.100093004
C57BL/6J both 0.1477083333 0.0047047905 0.1571491861 0.1382674805
CAST/EiJ both 0.091805 0.0051538398 0.1021469361 0.0814630639
DBA/2J both 0.18143 0.0038959367 0.1892477688 0.1736122312
NOD/ShiLtJ both 0.1294233333 0.0037300754 0.1369082771 0.1219383895
PWK/PhJ both 0.12925 0.0041322648 0.137541996 0.120958004
WSB/EiJ both 0.0898266667 0.0044986402 0.0988538486 0.0807994848




  GWAS USING LINEAR MIXED MODELS