Project measure / variable:   Auwerx2   heart_wt_CD

ID, description, units MPD:114655   heart_wt_CD   heart weight   [g]  CD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 21wks
Procedure organ weights
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  STRAIN COMPARISON PLOT
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Auwerx2 - heart weight CD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means0.12011   g 0.14484   g
Median of the strain means0.11262   g 0.1434   g
SD of the strain means± 0.04601 ± 0.04775
Coefficient of variation (CV)0.3831 0.3297
Min–max range of strain means0.07007   –   0.22793   g 0.08993   –   0.23618   g
Mean sample size per strain4.4   mice 4.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0148 0.0148 88.5436 < 0.0001
strain 7 0.128 0.0183 109.6338 < 0.0001
sex:strain 7 0.0058 0.0008 4.9946 0.0002
Residuals 63 0.0105 0.0002


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.1187 0.00899611   5 0.00402318 0.0758 0.1136, 0.1346 -0.03
129S1/SvImJ m 0.12466 0.01614   5 0.00721863 0.1295 0.1019, 0.1439 -0.42
A/J f 0.10542 0.00881062   5 0.00394023 0.0836 0.097, 0.1198 -0.32
A/J m 0.11474 0.00465757   5 0.00208293 0.0406 0.1081, 0.119 -0.63
C57BL/6J f 0.1154 0.00436348   5 0.00195141 0.0378 0.108, 0.1195 -0.1
C57BL/6J m 0.1434 0.0114   5 0.00509941 0.0795 0.128, 0.158 -0.03
CAST/EiJ f 0.0796 0.0   1   0.0 0.0 0.0796, 0.0796 -0.88
CAST/EiJ m 0.08993 0.0099143   3 0.00572402 0.1102 0.081, 0.1006 -1.15
DBA/2J f 0.14576 0.01229   5 0.00549787 0.0843 0.1318, 0.1618 0.56
DBA/2J m 0.2034 0.01759   5 0.00786492 0.0865 0.1836, 0.2239 1.23
NOD/ShiLtJ f 0.10553 0.01583   7 0.00598203 0.15 0.0726, 0.12 -0.32
NOD/ShiLtJ m 0.1487 0.00551317   5 0.00246556 0.0371 0.1413, 0.1547 0.08
NZO/HlLtJ f 0.22793 0.01149   4 0.00574708 0.0504 0.2128, 0.2407 2.34
NZO/HlLtJ m 0.23618 0.01325   5 0.00592768 0.0561 0.2187, 0.2543 1.91
PWK/PhJ f 0.11262 0.00892816   5 0.00399279 0.0793 0.0976, 0.1206 -0.16
PWK/PhJ m 0.14376 0.00522571   5 0.00233701 0.0364 0.1375, 0.1513 -0.02
WSB/EiJ f 0.07007 0.0075182   3 0.00434063 0.1073 0.0632, 0.0781 -1.09
WSB/EiJ m 0.0988 0.02756   5 0.01233 0.279 0.0703, 0.1438 -0.96


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.1187 0.0057748223 0.1302400616 0.1071599384
129S1/SvImJ m 0.12466 0.0057748223 0.1362000616 0.1131199384
A/J f 0.10542 0.0057748223 0.1169600616 0.0938799384
A/J m 0.11474 0.0057748223 0.1262800616 0.1031999384
C57BL/6J f 0.1154 0.0057748223 0.1269400616 0.1038599384
C57BL/6J m 0.1434 0.0057748223 0.1549400616 0.1318599384
DBA/2J f 0.14576 0.0057748223 0.1573000616 0.1342199384
DBA/2J m 0.2034 0.0057748223 0.2149400616 0.1918599384
NOD/ShiLtJ f 0.1055285714 0.0048806157 0.1152817036 0.0957754393
NOD/ShiLtJ m 0.1487 0.0057748223 0.1602400616 0.1371599384
NZO/HlLtJ f 0.227925 0.0064564476 0.2408271811 0.2150228189
NZO/HlLtJ m 0.23618 0.0057748223 0.2477200616 0.2246399384
PWK/PhJ f 0.11262 0.0057748223 0.1241600616 0.1010799384
PWK/PhJ m 0.14376 0.0057748223 0.1553000616 0.1322199384
WSB/EiJ f 0.0700666667 0.0074552636 0.0849648221 0.0551685112
WSB/EiJ m 0.0988 0.0057748223 0.1103400616 0.0872599384


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.12168 0.004083416 0.1298400558 0.1135199442
A/J both 0.11008 0.004083416 0.1182400558 0.1019199442
C57BL/6J both 0.1294 0.004083416 0.1375600558 0.1212399442
DBA/2J both 0.17458 0.004083416 0.1827400558 0.1664199442
NOD/ShiLtJ both 0.1271142857 0.0037805086 0.1346690294 0.119559542
NZO/HlLtJ both 0.2320525 0.0043311167 0.2407075462 0.2233974538
PWK/PhJ both 0.12819 0.004083416 0.1363500558 0.1200299442
WSB/EiJ both 0.0844333333 0.0047151227 0.0938557542 0.0750109125




  GWAS USING LINEAR MIXED MODELS