Project measure / variable:   Auwerx2   gastroc_wt_CD

ID, description, units MPD:114653   gastroc_wt_CD   gastrocnemius muscle weight   [g]  CD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 21wks
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  STRAIN COMPARISON PLOT
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Auwerx2 - gastrocnemius muscle weight CD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means0.2116   g 0.25073   g
Median of the strain means0.22142   g 0.25274   g
SD of the strain means± 0.04834 ± 0.05031
Coefficient of variation (CV)0.2285 0.2006
Min–max range of strain means0.12777   –   0.28407   g 0.19108   –   0.33122   g
Mean sample size per strain4.4   mice 4.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0268 0.0268 31.5761 < 0.0001
strain 7 0.1485 0.0212 25.0042 < 0.0001
sex:strain 7 0.0094 0.0013 1.585 0.1566
Residuals 62 0.0526 0.0008


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.22142 0.02831   5 0.01266 0.1279 0.1812, 0.2574 0.2
129S1/SvImJ m 0.22494 0.02392   5 0.0107 0.1063 0.1975, 0.2508 -0.51
A/J f 0.24472 0.01963   5 0.00877863 0.0802 0.2219, 0.2625 0.69
A/J m 0.26238 0.01627   4 0.00813371 0.062 0.2476, 0.2792 0.23
C57BL/6J f 0.22654 0.02009   5 0.00898613 0.0887 0.2022, 0.2543 0.31
C57BL/6J m 0.3001 0.02856   5 0.01277 0.0952 0.2669, 0.3324 0.98
CAST/EiJ f 0.1821 0.0   1   0.0 0.0 0.1821, 0.1821 -0.61
CAST/EiJ m 0.20323 0.00677225   3 0.00390996 0.0333 0.1968, 0.2103 -0.94
DBA/2J f 0.21806 0.00952171   5 0.00425824 0.0437 0.2033, 0.2283 0.13
DBA/2J m 0.25274 0.01382   5 0.00617945 0.0547 0.2396, 0.2738 0.04
NOD/ShiLtJ f 0.2435 0.04231   7 0.01599 0.1738 0.1518, 0.275 0.66
NOD/ShiLtJ m 0.2937 0.0131   5 0.00585747 0.0446 0.2758, 0.3062 0.85
NZO/HlLtJ f 0.28407 0.0163   4 0.00815101 0.0574 0.2695, 0.3072 1.5
NZO/HlLtJ m 0.33122 0.05727   5 0.02561 0.1729 0.2674, 0.4034 1.6
PWK/PhJ f 0.1562 0.03663   5 0.01638 0.2345 0.11, 0.2119 -1.15
PWK/PhJ m 0.19108 0.02965   5 0.01326 0.1551 0.1428, 0.219 -1.19
WSB/EiJ f 0.12777 0.00736637   3 0.00425297 0.0577 0.1207, 0.1354 -1.73
WSB/EiJ m 0.19722 0.03333   5 0.0149 0.169 0.1512, 0.2381 -1.06


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.22142 0.0130276665 0.2474619344 0.1953780656
129S1/SvImJ m 0.22494 0.0130276665 0.2509819344 0.1988980656
A/J f 0.24472 0.0130276665 0.2707619344 0.2186780656
A/J m 0.262375 0.014565374 0.2914907678 0.2332592322
C57BL/6J f 0.22654 0.0130276665 0.2525819344 0.2004980656
C57BL/6J m 0.3001 0.0130276665 0.3261419344 0.2740580656
DBA/2J f 0.21806 0.0130276665 0.2441019344 0.1920180656
DBA/2J m 0.25274 0.0130276665 0.2787819344 0.2266980656
NOD/ShiLtJ f 0.2435 0.0110103878 0.2655094516 0.2214905484
NOD/ShiLtJ m 0.2937 0.0130276665 0.3197419344 0.2676580656
NZO/HlLtJ f 0.284075 0.014565374 0.3131907678 0.2549592322
NZO/HlLtJ m 0.33122 0.0130276665 0.3572619344 0.3051780656
PWK/PhJ f 0.1562 0.0130276665 0.1822419344 0.1301580656
PWK/PhJ m 0.19108 0.0130276665 0.2171219344 0.1650380656
WSB/EiJ f 0.1277666667 0.0168186452 0.1613866594 0.094146674
WSB/EiJ m 0.19722 0.0130276665 0.2232619344 0.1711780656


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.22318 0.0092119514 0.2415944284 0.2047655716
A/J both 0.2535475 0.0097707499 0.2730789508 0.2340160492
C57BL/6J both 0.26332 0.0092119514 0.2817344284 0.2449055716
DBA/2J both 0.2354 0.0092119514 0.2538144284 0.2169855716
NOD/ShiLtJ both 0.2686 0.0085286097 0.2856484479 0.2515515521
NZO/HlLtJ both 0.3076475 0.0097707499 0.3271789508 0.2881160492
PWK/PhJ both 0.17364 0.0092119514 0.1920544284 0.1552255716
WSB/EiJ both 0.1624933333 0.0106370452 0.1837564837 0.141230183




  GWAS USING LINEAR MIXED MODELS