Project measure / variable:   Auwerx2   dist_treadmill_HFD

ID, description, units MPD:114648   dist_treadmill_HFD   distance traveled, treadmill test   [m]  HFD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 19wks
Procedure treadmill endurance test
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  STRAIN COMPARISON PLOT
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Auwerx2 - distance traveled, treadmill test HFD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains8 strains
Mean of the strain means468.4   m 433.0   m
Median of the strain means346.7   m 453.5   m
SD of the strain means± 412.2 ± 234.7
Coefficient of variation (CV)0.8799 0.5419
Min–max range of strain means36.34   –   1313.0   m 108.6   –   871.7   m
Mean sample size per strain4.1   mice 3.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 85760.6478 85760.6478 6.1276 0.0171
strain 7 4780621.2881 682945.8983 48.7966 < 0.0001
sex:strain 7 785439.058 112205.5797 8.0171 < 0.0001
Residuals 46 643804.8558 13995.7577


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 293.1 159.0   5 71.1 0.5423 73.0, 422.0 -0.43
129S1/SvImJ m 195.7 128.2   2   90.65 0.6552 105.0, 286.3 -1.01
A/J f 107.0 47.3   4 23.65 0.4422 38.3, 144.4 -0.88
A/J m 108.6 45.136   5 20.186 0.4155 60.5, 166.4 -1.38
C57BL/6J f 346.7 92.0   3 53.12 0.2654 255.0, 439.0 -0.3
C57BL/6J m 328.9 37.545   3 21.677 0.1142 294.6, 369.0 -0.44
CAST/EiJ f 964.6 184.3   5 82.44 0.1911 716.0, 1138.0 1.2
CAST/EiJ m 478.0 147.1   2   104.0 0.3077 374.0, 582.0 0.19
DBA/2J f 309.9 107.6   5 48.121 0.3472 163.4, 439.0 -0.38
DBA/2J m 501.0 93.3   5 41.725 0.1862 372.0, 616.0 0.29
NOD/ShiLtJ f 483.3 32.655   3 18.853 0.0676 449.0, 514.0 0.04
NOD/ShiLtJ m 429.0 114.1   5 51.02 0.2659 321.0, 582.0 -0.02
NZO/HlLtJ f 36.34 15.331   5 6.8564 0.4219 15.0, 52.7 -1.05
PWK/PhJ f 361.8 45.213   4 22.607 0.125 324.0, 420.0 -0.26
PWK/PhJ m 551.5 184.7   5 82.6 0.3349 308.0, 808.0 0.5
WSB/EiJ f 1313.0 146.0   3 84.3 0.1112 1168.0, 1460.0 2.05
WSB/EiJ m 871.7 82.23   3 47.477 0.0943 778.0, 932.0 1.87


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 293.14 52.9070084875 399.6362845366 186.6437154634
129S1/SvImJ m 195.65 83.6533255033 364.0354107405 27.2645892595
A/J f 106.975 59.1518337322 226.0414657875 -12.0914657875
A/J m 108.62 52.9070084875 215.1162845366 2.1237154634
C57BL/6J f 346.6666666667 68.3026542566 484.1527788144 209.180554519
C57BL/6J m 328.8666666667 68.3026542566 466.3527788144 191.380554519
CAST/EiJ f 964.6 52.9070084875 1071.0962845366 858.1037154634
CAST/EiJ m 478.0 83.6533255033 646.3854107405 309.6145892595
DBA/2J f 309.92 52.9070084875 416.4162845366 203.4237154634
DBA/2J m 501.0 52.9070084875 607.4962845366 394.5037154634
NOD/ShiLtJ f 483.3333333333 68.3026542566 620.819445481 345.8472211856
NOD/ShiLtJ m 429.0 52.9070084875 535.4962845366 322.5037154634
PWK/PhJ f 361.75 59.1518337322 480.8164657875 242.6835342125
PWK/PhJ m 551.54 52.9070084875 658.0362845366 445.0437154634
WSB/EiJ f 1312.6666666667 68.3026542566 1450.1527788144 1175.180554519
WSB/EiJ m 871.6666666667 68.3026542566 1009.1527788144 734.180554519


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 244.395 49.4899747799 344.0131524251 144.7768475749
A/J both 107.7975 39.6802563657 187.6697134024 27.9252865976
C57BL/6J both 337.7666666667 48.2972699979 434.9840288853 240.549304448
CAST/EiJ both 721.3 49.4899747799 820.9181524251 621.6818475749
DBA/2J both 405.46 37.4109044738 480.764244967 330.155755033
NOD/ShiLtJ both 456.1666666667 43.1983915372 543.1205188723 369.212814461
PWK/PhJ both 456.645 39.6802563657 536.5172134024 376.7727865976
WSB/EiJ both 1092.1666666667 48.2972699979 1189.3840288853 994.949304448




  GWAS USING LINEAR MIXED MODELS