Project measure / variable:   Auwerx2   dist_treadmill_CD

ID, description, units MPD:114647   dist_treadmill_CD   distance traveled, treadmill test   [m]  CD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 19wks
Procedure treadmill endurance test
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  STRAIN COMPARISON PLOT
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Auwerx2 - distance traveled, treadmill test CD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means489.7   m 400.4   m
Median of the strain means550.5   m 403.0   m
SD of the strain means± 298.5 ± 219.0
Coefficient of variation (CV)0.6096 0.5468
Min–max range of strain means103.2   –   1060.0   m 81.22   –   719.4   m
Mean sample size per strain4.1   mice 4.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 25121.5794 25121.5794 1.2398 0.2702
strain 7 2371935.7831 338847.969 16.7234 < 0.0001
sex:strain 7 252912.8752 36130.4107 1.7832 0.1085
Residuals 57 1154928.9015 20261.9106


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 301.0 164.7   5 73.64 0.5471 67.7, 435.8 -0.63
129S1/SvImJ m 346.8 103.6   5 46.325 0.2987 210.4, 450.2 -0.24
A/J f 111.0 55.58   4 27.791 0.5007 38.0, 160.0 -1.27
A/J m 112.5 27.818   3 16.061 0.2473 81.2, 134.4 -1.31
C57BL/6J f 621.8 136.0   5 60.83 0.2188 477.4, 794.0 0.44
C57BL/6J m 352.8 52.91   5 23.663 0.15 277.0, 426.0 -0.22
CAST/EiJ f 1060.0 0.0   1   0.0 0.0 1060.0, 1060.0 1.91
CAST/EiJ m 696.7 134.3   3 77.55 0.1928 542.0, 784.0 1.35
DBA/2J f 422.4 280.9   5 125.6 0.665 149.0, 802.0 -0.23
DBA/2J m 447.5 209.4   5 93.66 0.468 241.1, 736.4 0.21
NOD/ShiLtJ f 550.5 119.6   6 48.817 0.2172 423.0, 760.0 0.2
NOD/ShiLtJ m 443.9 34.948   5 15.629 0.0787 405.0, 479.6 0.2
NZO/HlLtJ f 103.2 47.759   4 23.879 0.4626 62.0, 171.0 -1.29
NZO/HlLtJ m 81.22 54.35   4 27.173 0.6691 39.0, 161.0 -1.46
PWK/PhJ f 606.8 84.39   5 37.74 0.1391 512.0, 720.0 0.39
PWK/PhJ m 403.0 83.24   5 37.224 0.2066 329.0, 538.0 0.01
WSB/EiJ f 630.5 94.05   2   66.5 0.1492 564.0, 697.0 0.47
WSB/EiJ m 719.4 254.6   5 113.9 0.3539 460.0, 1137.0 1.46


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 300.96 63.6583231834 428.4335933712 173.4864066288
129S1/SvImJ m 346.82 63.6583231834 474.2935933712 219.3464066288
A/J f 111.0 71.1721689859 253.5198100571 -31.5198100571
A/J m 112.5 82.1825418456 277.0677014026 -52.0677014026
C57BL/6J f 621.78 63.6583231834 749.2535933712 494.3064066288
C57BL/6J m 352.8 63.6583231834 480.2735933712 225.3264066288
DBA/2J f 422.4 63.6583231834 549.8735933712 294.9264066288
DBA/2J m 447.5 63.6583231834 574.9735933712 320.0264066288
NOD/ShiLtJ f 550.5 58.1118326342 666.8669376261 434.1330623739
NOD/ShiLtJ m 443.92 63.6583231834 571.3935933712 316.4464066288
NZO/HlLtJ f 103.25 71.1721689859 245.7698100571 -39.2698100571
NZO/HlLtJ m 81.225 71.1721689859 223.7448100571 -61.2948100571
PWK/PhJ f 606.8 63.6583231834 734.2735933712 479.3264066288
PWK/PhJ m 402.98 63.6583231834 530.4535933712 275.5064066288
WSB/EiJ f 630.5 100.6526466434 832.0534482896 428.9465517104
WSB/EiJ m 719.4 63.6583231834 846.8735933712 591.9264066288


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 323.89 45.013232002 414.027442295 233.752557705
A/J both 111.75 54.3586419587 220.6013029362 2.8986970638
C57BL/6J both 487.29 45.013232002 577.427442295 397.152557705
DBA/2J both 434.95 45.013232002 525.087442295 344.812557705
NOD/ShiLtJ both 497.21 43.0968885264 583.5100306771 410.9099693229
NZO/HlLtJ both 92.2375 50.3263233217 193.0142241448 -8.5392241448
PWK/PhJ both 504.89 45.013232002 595.027442295 414.752557705
WSB/EiJ both 674.95 59.5469087922 794.190628064 555.709371936




  GWAS USING LINEAR MIXED MODELS