Project measure / variable:   Auwerx2   horiz_act_night_HFD

ID, description, units MPD:114628   horiz_act_night_HFD   horizontal activity (beam breaks) at night, basal activity test, for 48h   [n/h]  HFD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 19wks
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  STRAIN COMPARISON PLOT
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Auwerx2 - horizontal activity (beam breaks) at night, basal activity test, for 48h HFD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains8 strains
Mean of the strain means58574.0   n/h 53544.0   n/h
Median of the strain means63499.0   n/h 52834.0   n/h
SD of the strain means± 27151.0 ± 22007.0
Coefficient of variation (CV)0.4635 0.411
Min–max range of strain means18130.0   –   98354.0   n/h 30782.0   –   99458.0   n/h
Mean sample size per strain3.8   mice 4.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 2549677825.4464 2549677825.4464 1.5252 0.2237
strain 6 10182163751.1606 1697027291.8601 1.0151 0.4287
sex:strain 6 8338568825.2252 1389761470.8709 0.8313 0.5525
Residuals 42 70212175063.15 1671718453.8845


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 55980.0 8654.0   5 3870.0 0.1546 49608.0, 71006.0 -0.1
129S1/SvImJ m 30782.0 18283.0   2   12928.0 0.5939 17854.0, 43710.0 -1.03
A/J f 63499.0 6342.0   4 3171.0 0.0999 58229.0, 71383.0 0.18
A/J m 50104.0 3681.0   5 1646.0 0.0735 47487.0, 56446.0 -0.16
C57BL/6J f 38240.0 9536.0   3 5506.0 0.2494 28174.0, 47139.0 -0.75
C57BL/6J m 55564.0 11644.0   4 5822.0 0.2096 41132.0, 69308.0 0.09
CAST/EiJ f 98354.0 116675.0   5 52179.0 1.1863 36632.0, 306794.0 1.47
CAST/EiJ m 32479.0 155.6   2   110.0 0.0048 32369.0, 32589.0 -0.96
DBA/2J f 68686.0 19940.0   5 8917.0 0.2903 36833.0, 89502.0 0.37
DBA/2J m 63785.0 11290.0   5 5049.0 0.177 50800.0, 78002.0 0.47
NOD/ShiLtJ f 80740.0 0.0   1   0.0 0.0 80740.0, 80740.0 0.82
NOD/ShiLtJ m 99458.0 29511.0   5 13198.0 0.2967 66801.0, 147707.0 2.09
NZO/HlLtJ f 23940.0 5059.0   5 2263.0 0.2113 18307.0, 30370.0 -1.28
PWK/PhJ f 18130.0 3475.0   3 2007.0 0.1917 15129.0, 21938.0 -1.49
PWK/PhJ m 39723.0 10241.0   5 4580.0 0.2578 26768.0, 54061.0 -0.63
WSB/EiJ f 79594.0 64669.0   3 37336.0 0.8125 37368.0, 154043.0 0.77
WSB/EiJ m 56456.0 29388.0   5 13143.0 0.5205 36483.0, 108169.0 0.13


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 55980.0 18285.0674260968 92880.7600074074 19079.2399925925
129S1/SvImJ m 30782.0 28911.2301181092 89127.2245073297 -27563.2245073296
A/J f 63498.75 20443.3268689597 104755.0538989843 22242.4461010157
A/J m 50103.8000000001 18285.0674260968 87004.5600074075 13203.0399925927
C57BL/6J f 38240.3333333333 23605.9205418508 85879.0096570285 -9398.3429903619
C57BL/6J m 55564.0 20443.3268689597 96820.3038989843 14307.6961010157
CAST/EiJ f 98354.0 18285.0674260968 135254.7600074075 61453.2399925926
CAST/EiJ m 32479.0000000001 28911.2301181091 90824.2245073297 -25866.2245073295
DBA/2J f 68686.0 18285.0674260968 105586.7600074075 31785.2399925926
DBA/2J m 63785.4 18285.0674260968 100686.1600074074 26884.6399925926
PWK/PhJ f 18130.3333333334 23605.9205418508 65769.0096570286 -29508.3429903618
PWK/PhJ m 39723.4000000001 18285.0674260968 76624.1600074075 2822.6399925926
WSB/EiJ f 79593.6666666667 23605.9205418508 127232.3429903619 31954.9903429715
WSB/EiJ m 56456.4 18285.0674260967 93357.1600074074 19555.6399925926


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 43381.0 17104.1144006286 77898.5003148221 8863.4996851779
A/J both 56801.275 13713.8005695726 84476.8450055556 29125.7049944445
C57BL/6J both 46902.1666666666 15613.8488056221 78412.1892518662 15392.1440814671
CAST/EiJ both 65416.5000000001 17104.1144006286 99934.0003148222 30898.999685178
DBA/2J both 66235.7 12929.4951714463 92328.4776321752 40142.9223678249
PWK/PhJ both 28926.8666666667 14929.6950354409 59056.2110463494 -1202.477713016
WSB/EiJ both 68025.0333333333 14929.6950354409 98154.3777130161 37895.6889536506




  GWAS USING LINEAR MIXED MODELS