Project measure / variable:   Auwerx2   temp_t5_HFD

ID, description, units MPD:114618   temp_t5_HFD   body temperature (rectal) in cold (4°C) room, 5h exposed to cold   [°C]  HFD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 18wks
Procedure body temperature
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  STRAIN COMPARISON PLOT
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Auwerx2 - body temperature (rectal) in cold (4°C) room, 5h exposed to cold HFD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means34.733   °C 34.406   °C
Median of the strain means34.833   °C 34.72   °C
SD of the strain means± 1.0189 ± 1.4584
Coefficient of variation (CV)0.0293 0.0424
Min–max range of strain means32.6   –   36.3   °C 32.02   –   36.82   °C
Mean sample size per strain4.2   mice 3.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 2.4415 2.4415 5.4608 0.0233
strain 7 59.7981 8.5426 19.1066 < 0.0001
sex:strain 7 23.4235 3.3462 7.4842 < 0.0001
Residuals 52 23.2493 0.4471


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 34.9 0.78422   5 0.35071 0.0225 33.7, 35.7 0.16
129S1/SvImJ m 34.55 0.07071   2   0.05 0.002 34.5, 34.6 0.1
A/J f 34.425 0.87321   4 0.43661 0.0254 33.2, 35.1 -0.3
A/J m 35.24 0.32863   5 0.14697 0.0093 34.8, 35.7 0.57
C57BL/6J f 34.367 0.20817   3 0.12019 0.0061 34.2, 34.6 -0.36
C57BL/6J m 32.995 0.71654   4 0.35827 0.0217 32.3, 33.98 -0.97
CAST/EiJ f 34.48 1.0616   5 0.47476 0.0308 33.1, 35.6 -0.25
CAST/EiJ m 35.05 0.35355   2   0.25 0.0101 34.8, 35.3 0.44
DBA/2J f 35.02 0.30332   5 0.13565 0.0087 34.6, 35.4 0.28
DBA/2J m 34.72 0.68337   5 0.30561 0.0197 34.0, 35.8 0.22
NOD/ShiLtJ f 34.833 0.53914   6 0.2201 0.0155 34.1, 35.4 0.1
NOD/ShiLtJ m 32.02 0.94446   5 0.42237 0.0295 30.8, 32.8 -1.64
NZO/HlLtJ f 32.6 0.26458   3 0.15275 0.0081 32.4, 32.9 -2.09
NZO/HlLtJ m 33.1 0.0   1   0.0 0.0 33.1, 33.1 -0.9
PWK/PhJ f 35.675 0.60759   4 0.3038 0.017 34.8, 36.2 0.92
PWK/PhJ m 35.16 0.16733   5 0.07483 0.0048 35.0, 35.4 0.52
WSB/EiJ f 36.3 0.95394   3 0.55076 0.0263 35.7, 37.4 1.54
WSB/EiJ m 36.82 0.614   5 0.27459 0.0167 36.2, 37.7 1.66


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 34.9 0.299032414 35.5000524381 34.2999475619
129S1/SvImJ m 34.55 0.4728117612 35.49876621 33.60123379
A/J f 34.425 0.3343284026 35.0958790209 33.7541209791
A/J m 35.24 0.299032414 35.8400524381 34.6399475619
C57BL/6J f 34.3666666667 0.3860491865 35.1413310333 33.5920023001
C57BL/6J m 32.995 0.3343284026 33.6658790209 32.3241209791
CAST/EiJ f 34.48 0.299032414 35.0800524381 33.8799475619
CAST/EiJ m 35.05 0.4728117612 35.99876621 34.10123379
DBA/2J f 35.02 0.299032414 35.6200524381 34.4199475619
DBA/2J m 34.72 0.299032414 35.3200524381 34.1199475619
NOD/ShiLtJ f 34.8333333333 0.2729779976 35.3811037601 34.2855629066
NOD/ShiLtJ m 32.02 0.299032414 32.6200524381 31.4199475619
PWK/PhJ f 35.675 0.3343284026 36.3458790209 35.0041209791
PWK/PhJ m 35.16 0.299032414 35.7600524381 34.5599475619
WSB/EiJ f 36.3 0.3860491865 37.0746643666 35.5253356334
WSB/EiJ m 36.82 0.299032414 37.4200524381 36.2199475619


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 34.725 0.2797192102 35.2862976594 34.1637023406
A/J both 34.8325 0.2242743105 35.2825393286 34.3824606714
C57BL/6J both 33.6808333333 0.2553475353 34.1932256492 33.1684410175
CAST/EiJ both 34.765 0.2797192102 35.3262976594 34.2037023406
DBA/2J both 34.87 0.2114478477 35.2943011481 34.4456988519
NOD/ShiLtJ both 33.4266666667 0.2024459013 33.8329040877 33.0204292456
PWK/PhJ both 35.4175 0.2242743105 35.8675393286 34.9674606714
WSB/EiJ both 36.56 0.2441589436 37.0499407641 36.0700592359




  GWAS USING LINEAR MIXED MODELS