Project measure / variable:   Auwerx2   temp_t4_CD

ID, description, units MPD:114615   temp_t4_CD   body temperature (rectal) in cold (4°C) room, 4h exposed to cold   [°C]  CD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 18wks
Procedure body temperature
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  STRAIN COMPARISON PLOT
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Auwerx2 - body temperature (rectal) in cold (4°C) room, 4h exposed to cold CD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means34.686   °C 34.33   °C
Median of the strain means34.65   °C 34.58   °C
SD of the strain means± 1.0523 ± 1.3704
Coefficient of variation (CV)0.0303 0.0399
Min–max range of strain means32.58   –   36.16   °C 31.38   –   35.72   °C
Mean sample size per strain4.3   mice 4.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.9185 0.9185 1.2075 0.2761
strain 7 82.857 11.8367 15.5607 < 0.0001
sex:strain 7 25.8237 3.6891 4.8497 0.0002
Residuals 62 47.162 0.7607


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 34.56 0.54589   5 0.24413 0.0158 34.1, 35.5 -0.12
129S1/SvImJ m 34.58 0.35637   5 0.15937 0.0103 34.2, 35.1 0.18
A/J f 34.52 0.85849   5 0.38393 0.0249 33.6, 35.9 -0.16
A/J m 34.54 0.61482   5 0.27495 0.0178 33.9, 35.2 0.15
C57BL/6J f 32.58 1.4601   5 0.65299 0.0448 30.8, 34.4 -2.0
C57BL/6J m 33.02 1.0183   5 0.45541 0.0308 31.5, 34.2 -0.96
CAST/EiJ f 36.0 0.0   1   0.0 0.0 36.0, 36.0 1.25
CAST/EiJ m 34.767 0.56862   3 0.3283 0.0164 34.3, 35.4 0.32
DBA/2J f 34.9 0.6   5 0.26833 0.0172 34.4, 35.8 0.2
DBA/2J m 35.16 0.84143   5 0.3763 0.0239 34.4, 36.5 0.61
NOD/ShiLtJ f 34.033 1.6836   6 0.68735 0.0495 32.1, 36.1 -0.62
NOD/ShiLtJ m 34.18 1.0208   5 0.45651 0.0299 33.0, 35.2 -0.11
NZO/HlLtJ f 34.65 0.36968   4 0.18484 0.0107 34.3, 35.1 -0.03
NZO/HlLtJ m 31.38 0.55857   5 0.2498 0.0178 30.4, 31.8 -2.15
PWK/PhJ f 36.16 0.39115   5 0.17493 0.0108 35.8, 36.7 1.4
PWK/PhJ m 35.62 0.70143   5 0.31369 0.0197 34.5, 36.3 0.94
WSB/EiJ f 34.767 0.72342   3 0.41767 0.0208 34.3, 35.6 0.08
WSB/EiJ m 35.72 0.32711   5 0.14629 0.0092 35.2, 36.0 1.01


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 34.56 0.3900454895 35.3396898238 33.7803101762
129S1/SvImJ m 34.58 0.3900454895 35.3596898238 33.8003101762
A/J f 34.52 0.3900454895 35.2996898238 33.7403101762
A/J m 34.54 0.3900454895 35.3196898238 33.7603101762
C57BL/6J f 32.58 0.3900454895 33.3596898238 31.8003101762
C57BL/6J m 33.02 0.3900454895 33.7996898238 32.2403101762
DBA/2J f 34.9 0.3900454895 35.6796898238 34.1203101762
DBA/2J m 35.16 0.3900454895 35.9396898238 34.3803101762
NOD/ShiLtJ f 34.0333333333 0.3560611884 34.7450895073 33.3215771594
NOD/ShiLtJ m 34.18 0.3900454895 34.9596898238 33.4003101762
NZO/HlLtJ f 34.65 0.4360841144 35.5217197237 33.7782802763
NZO/HlLtJ m 31.38 0.3900454895 32.1596898238 30.6003101762
PWK/PhJ f 36.16 0.3900454895 36.9396898238 35.3803101762
PWK/PhJ m 35.62 0.3900454895 36.3996898238 34.8403101762
WSB/EiJ f 34.7666666667 0.5035465617 35.773241901 33.7600914324
WSB/EiJ m 35.72 0.3900454895 36.4996898238 34.9403101762


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 34.57 0.2758038106 35.1213239617 34.0186760383
A/J both 34.53 0.2758038106 35.0813239617 33.9786760383
C57BL/6J both 32.8 0.2758038106 33.3513239617 32.2486760383
DBA/2J both 35.03 0.2758038106 35.5813239617 34.4786760383
NOD/ShiLtJ both 34.1066666667 0.2640620447 34.6345191727 33.5788141606
NZO/HlLtJ both 33.015 0.2925341171 33.5997673679 32.4302326321
PWK/PhJ both 35.89 0.2758038106 36.4413239617 35.3386760383
WSB/EiJ both 35.2433333333 0.3184708086 35.8799474087 34.606719258




  GWAS USING LINEAR MIXED MODELS