Project measure / variable:   Auwerx2   temp_t3_CD

ID, description, units MPD:114613   temp_t3_CD   body temperature (rectal) in cold (4°C) room, 3h exposed to cold   [°C]  CD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 18wks
Procedure body temperature
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  STRAIN COMPARISON PLOT
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Auwerx2 - body temperature (rectal) in cold (4°C) room, 3h exposed to cold CD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means34.913   °C 34.696   °C
Median of the strain means34.94   °C 34.68   °C
SD of the strain means± 0.62856 ± 1.0094
Coefficient of variation (CV)0.018 0.0291
Min–max range of strain means33.86   –   36.16   °C 32.9   –   36.1   °C
Mean sample size per strain4.3   mice 4.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.3129 0.3129 0.7925 0.3768
strain 7 41.3363 5.9052 14.9584 < 0.0001
sex:strain 7 13.8609 1.9801 5.0159 0.0002
Residuals 62 24.476 0.3948


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 34.94 0.34351   5 0.15362 0.0098 34.4, 35.2 0.04
129S1/SvImJ m 34.68 0.57619   5 0.25768 0.0166 34.1, 35.3 -0.02
A/J f 34.64 0.82037   5 0.36688 0.0237 33.6, 35.3 -0.43
A/J m 35.14 0.11402   5 0.05099 0.0032 35.0, 35.3 0.44
C57BL/6J f 33.86 0.78294   5 0.35014 0.0231 33.1, 35.1 -1.67
C57BL/6J m 33.56 0.68044   5 0.3043 0.0203 32.5, 34.2 -1.12
CAST/EiJ f 35.4 0.0   1   0.0 0.0 35.4, 35.4 0.78
CAST/EiJ m 34.6 0.96437   3 0.55678 0.0279 33.5, 35.3 -0.09
DBA/2J f 34.68 0.60581   5 0.27092 0.0175 33.8, 35.2 -0.37
DBA/2J m 34.42 0.28636   5 0.12806 0.0083 34.0, 34.8 -0.27
NOD/ShiLtJ f 34.567 1.2565   6 0.51294 0.0363 33.0, 36.1 -0.55
NOD/ShiLtJ m 35.04 0.39115   5 0.17493 0.0112 34.6, 35.5 0.34
NZO/HlLtJ f 35.0 0.3559   4 0.17795 0.0102 34.5, 35.3 0.14
NZO/HlLtJ m 32.9 0.33912   5 0.15166 0.0103 32.4, 33.3 -1.78
PWK/PhJ f 36.16 0.40988   5 0.1833 0.0113 35.7, 36.7 1.98
PWK/PhJ m 35.82 0.46583   5 0.20833 0.013 35.0, 36.1 1.11
WSB/EiJ f 34.967 0.76376   3 0.44096 0.0218 34.3, 35.8 0.09
WSB/EiJ m 36.1 0.66708   5 0.29833 0.0185 35.3, 37.0 1.39


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 34.94 0.2809890366 35.5016890808 34.3783109192
129S1/SvImJ m 34.68 0.2809890366 35.2416890808 34.1183109192
A/J f 34.64 0.2809890366 35.2016890808 34.0783109192
A/J m 35.14 0.2809890366 35.7016890808 34.5783109192
C57BL/6J f 33.86 0.2809890366 34.4216890808 33.2983109192
C57BL/6J m 33.56 0.2809890366 34.1216890808 32.9983109192
DBA/2J f 34.68 0.2809890366 35.2416890808 34.1183109192
DBA/2J m 34.42 0.2809890366 34.9816890808 33.8583109192
NOD/ShiLtJ f 34.5666666667 0.256506723 35.0794162998 34.0539170335
NOD/ShiLtJ m 35.04 0.2809890366 35.6016890808 34.4783109192
NZO/HlLtJ f 35.0 0.3141552934 35.6279874835 34.3720125165
NZO/HlLtJ m 32.9 0.2809890366 33.4616890808 32.3383109192
PWK/PhJ f 36.16 0.2809890366 36.7216890808 35.5983109192
PWK/PhJ m 35.82 0.2809890366 36.3816890808 35.2583109192
WSB/EiJ f 34.9666666667 0.3627552865 35.6918041519 34.2415291814
WSB/EiJ m 36.1 0.2809890366 36.6616890808 35.5383109192


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 34.81 0.1986892532 35.207174158 34.412825842
A/J both 34.89 0.1986892532 35.287174158 34.492825842
C57BL/6J both 33.71 0.1986892532 34.107174158 33.312825842
DBA/2J both 34.55 0.1986892532 34.947174158 34.152825842
NOD/ShiLtJ both 34.8033333333 0.1902304771 35.1835986387 34.423068028
NZO/HlLtJ both 33.95 0.2107417775 34.3712668106 33.5287331894
PWK/PhJ both 35.99 0.1986892532 36.387174158 35.592825842
WSB/EiJ both 35.5333333333 0.2294265877 35.9919505474 35.0747161193




  GWAS USING LINEAR MIXED MODELS