Project measure / variable:   Auwerx2   temp_t2_HFD

ID, description, units MPD:114612   temp_t2_HFD   body temperature (rectal) in cold (4°C) room, 2h exposed to cold   [°C]  HFD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 18wks
Procedure body temperature
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  STRAIN COMPARISON PLOT
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Auwerx2 - body temperature (rectal) in cold (4°C) room, 2h exposed to cold HFD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means35.493   °C 35.228   °C
Median of the strain means35.425   °C 35.24   °C
SD of the strain means± 0.84491 ± 1.1344
Coefficient of variation (CV)0.0238 0.0322
Min–max range of strain means33.825   –   37.1   °C 33.675   –   36.94   °C
Mean sample size per strain4.3   mice 3.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 2.2685 2.2685 6.7717 0.012
strain 7 34.9552 4.9936 14.9063 < 0.0001
sex:strain 7 11.7426 1.6775 5.0075 0.0002
Residuals 52 17.42 0.335


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 35.66 0.55498   5 0.24819 0.0156 34.9, 36.2 0.2
129S1/SvImJ m 36.05 0.35355   2   0.25 0.0098 35.8, 36.3 0.72
A/J f 35.425 0.3304   4 0.1652 0.0093 35.1, 35.8 -0.08
A/J m 35.06 1.23   5 0.55009 0.0351 33.2, 36.3 -0.15
C57BL/6J f 35.6 0.60828   3 0.35119 0.0171 34.9, 36.0 0.13
C57BL/6J m 33.675 0.22174   4 0.11087 0.0066 33.5, 34.0 -1.37
CAST/EiJ f 35.16 0.30496   5 0.13638 0.0087 34.7, 35.4 -0.39
CAST/EiJ m 36.35 0.91924   2   0.65 0.0253 35.7, 37.0 0.99
DBA/2J f 35.42 0.64187   5 0.28705 0.0181 34.5, 36.2 -0.09
DBA/2J m 35.24 0.38471   5 0.17205 0.0109 34.9, 35.9 0.01
NOD/ShiLtJ f 35.35 0.52058   6 0.21252 0.0147 34.4, 36.0 -0.17
NOD/ShiLtJ m 33.9 0.52915   5 0.23664 0.0156 33.4, 34.8 -1.17
NZO/HlLtJ f 33.825 1.2712   4 0.63558 0.0376 32.0, 34.9 -1.97
NZO/HlLtJ m 34.2 0.0   1   0.0 0.0 34.2, 34.2 -0.91
PWK/PhJ f 35.9 0.52915   4 0.26458 0.0147 35.4, 36.6 0.48
PWK/PhJ m 35.64 0.50299   5 0.22494 0.0141 34.9, 36.2 0.36
WSB/EiJ f 37.1 0.52915   3 0.30551 0.0143 36.5, 37.5 1.9
WSB/EiJ m 36.94 0.33615   5 0.15033 0.0091 36.7, 37.4 1.51


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 35.66 0.2588435821 36.1794076471 35.1405923529
129S1/SvImJ m 36.05 0.4092676386 36.8712555994 35.2287444006
A/J f 35.425 0.2893959226 36.0057154034 34.8442845966
A/J m 35.06 0.2588435821 35.5794076471 34.5405923529
C57BL/6J f 35.6 0.3341656276 36.270552389 34.929447611
C57BL/6J m 33.675 0.2893959226 34.2557154034 33.0942845966
CAST/EiJ f 35.16 0.2588435821 35.6794076471 34.6405923529
CAST/EiJ m 36.35 0.4092676386 37.1712555994 35.5287444006
DBA/2J f 35.42 0.2588435821 35.9394076471 34.9005923529
DBA/2J m 35.24 0.2588435821 35.7594076471 34.7205923529
NOD/ShiLtJ f 35.35 0.2362907813 35.8241521414 34.8758478586
NOD/ShiLtJ m 33.9 0.2588435821 34.4194076471 33.3805923529
PWK/PhJ f 35.9 0.2893959226 36.4807154034 35.3192845966
PWK/PhJ m 35.64 0.2588435821 36.1594076471 35.1205923529
WSB/EiJ f 37.1 0.3341656276 37.770552389 36.429447611
WSB/EiJ m 36.94 0.2588435821 37.4594076471 36.4205923529


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 35.855 0.2421260003 36.3408613648 35.3691386352
A/J both 35.2425 0.1941326866 35.6320557353 34.8529442647
C57BL/6J both 34.6375 0.2210297868 35.0810287156 34.1939712844
CAST/EiJ both 35.755 0.2421260003 36.2408613648 35.2691386352
DBA/2J both 35.33 0.1830300522 35.6972766694 34.9627233306
NOD/ShiLtJ both 34.625 0.1752379335 34.9766406394 34.2733593606
PWK/PhJ both 35.77 0.1941326866 36.1595557353 35.3804442647
WSB/EiJ both 37.02 0.2113448998 37.4440945679 36.5959054321




  GWAS USING LINEAR MIXED MODELS