Project measure / variable:   Auwerx2   temp_t1_CD

ID, description, units MPD:114609   temp_t1_CD   body temperature (rectal) in cold (4°C) room, 1h exposed to cold   [°C]  CD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 18wks
Procedure body temperature
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  STRAIN COMPARISON PLOT
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Auwerx2 - body temperature (rectal) in cold (4°C) room, 1h exposed to cold CD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means35.76   °C 35.733   °C
Median of the strain means35.88   °C 35.7   °C
SD of the strain means± 0.68436 ± 0.71452
Coefficient of variation (CV)0.0191 0.02
Min–max range of strain means34.72   –   37.1   °C 34.733   –   37.06   °C
Mean sample size per strain4.3   mice 4.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1.8743 1.8743 5.7171 0.0198
strain 7 20.9031 2.9862 9.1085 < 0.0001
sex:strain 7 1.8432 0.2633 0.8032 0.5878
Residuals 62 20.3262 0.3278


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 36.0 0.45277   5 0.20248 0.0126 35.5, 36.5 0.35
129S1/SvImJ m 36.02 0.60581   5 0.27092 0.0168 35.4, 36.7 0.4
A/J f 34.72 0.54498   5 0.24372 0.0157 34.0, 35.5 -1.52
A/J m 35.04 0.57271   5 0.25612 0.0163 34.3, 35.9 -0.97
C57BL/6J f 35.12 0.49193   5 0.22 0.014 34.7, 35.7 -0.93
C57BL/6J m 35.34 0.73348   5 0.32802 0.0208 34.2, 35.9 -0.55
CAST/EiJ f 37.1 0.0   1   0.0 0.0 37.1, 37.1 1.96
CAST/EiJ m 34.733 0.51316   3 0.29627 0.0148 34.3, 35.3 -1.4
DBA/2J f 35.66 0.32863   5 0.14697 0.0092 35.2, 36.1 -0.15
DBA/2J m 35.78 0.59749   5 0.26721 0.0167 35.2, 36.7 0.07
NOD/ShiLtJ f 35.3 0.54406   6 0.22211 0.0154 34.6, 35.9 -0.67
NOD/ShiLtJ m 35.46 0.45056   5 0.20149 0.0127 34.7, 35.9 -0.38
NZO/HlLtJ f 35.925 0.51235   4 0.25617 0.0143 35.4, 36.5 0.24
NZO/HlLtJ m 35.7 0.86023   5 0.38471 0.0241 34.8, 37.0 -0.05
PWK/PhJ f 35.88 0.50695   5 0.22672 0.0141 35.2, 36.6 0.18
PWK/PhJ m 36.46 0.38471   5 0.17205 0.0106 36.0, 36.9 1.02
WSB/EiJ f 36.133 0.45092   3 0.26034 0.0125 35.7, 36.6 0.55
WSB/EiJ m 37.06 0.7893   5 0.35299 0.0213 36.1, 37.7 1.86


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 36.0 0.2560630383 36.5118627201 35.4881372799
129S1/SvImJ m 36.02 0.2560630383 36.5318627201 35.5081372799
A/J f 34.72 0.2560630383 35.2318627201 34.2081372799
A/J m 35.04 0.2560630383 35.5518627201 34.5281372799
C57BL/6J f 35.12 0.2560630383 35.6318627201 34.6081372799
C57BL/6J m 35.34 0.2560630383 35.8518627201 34.8281372799
DBA/2J f 35.66 0.2560630383 36.1718627201 35.1481372799
DBA/2J m 35.78 0.2560630383 36.2918627201 35.2681372799
NOD/ShiLtJ f 35.3 0.2337525037 35.7672645969 34.8327354031
NOD/ShiLtJ m 35.46 0.2560630383 35.9718627201 34.9481372799
NZO/HlLtJ f 35.925 0.2862871801 36.4972799186 35.3527200814
NZO/HlLtJ m 35.7 0.2560630383 36.2118627201 35.1881372799
PWK/PhJ f 35.88 0.2560630383 36.3918627201 35.3681372799
PWK/PhJ m 36.46 0.2560630383 36.9718627201 35.9481372799
WSB/EiJ f 36.1333333333 0.3305759609 36.7941452635 35.4725214032
WSB/EiJ m 37.06 0.2560630383 37.5718627201 36.5481372799


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 36.01 0.1810639108 36.3719416004 35.6480583996
A/J both 34.88 0.1810639108 35.2419416004 34.5180583996
C57BL/6J both 35.23 0.1810639108 35.5919416004 34.8680583996
DBA/2J both 35.72 0.1810639108 36.0819416004 35.3580583996
NOD/ShiLtJ both 35.38 0.1733554964 35.7265326996 35.0334673004
NZO/HlLtJ both 35.8125 0.1920472787 36.1963970401 35.4286029599
PWK/PhJ both 36.17 0.1810639108 36.5319416004 35.8080583996
WSB/EiJ both 36.5966666667 0.2090745953 37.0146008275 36.1787325058




  GWAS USING LINEAR MIXED MODELS