Project measure / variable:   Auwerx2   ogtt_ins_t15_CD

ID, description, units MPD:114603   ogtt_ins_t15_CD   insulin, glucose tolerance test (20% glucose oral gavage, overnight fast), after 15 min   [µg/L]  CD  
Data set, strains Auwerx2   inbred w/CC8   8 strains     sex: both     age: 16wks
Procedure hormone quantification
Ontology mappings

  STRAIN COMPARISON PLOT
Dimensions Width:   px    Height:   px
Download Plot   
Visualization Options

Auwerx2 - insulin, glucose tolerance test (20% glucose oral gavage, overnight fast), after 15 min CD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means0.71211   µg/L 0.90246   µg/L
Median of the strain means0.57135   µg/L 0.83167   µg/L
SD of the strain means± 0.49801 ± 0.44985
Coefficient of variation (CV)0.6993 0.4985
Min–max range of strain means0.3322   –   1.87   µg/L 0.3251   –   1.6167   µg/L
Mean sample size per strain4.4   mice 4.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1.8778 1.8778 7.1862 0.0097
strain 6 6.0321 1.0053 3.8474 0.0029
sex:strain 6 1.9707 0.3285 1.257 0.2927
Residuals 54 14.1105 0.2613


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.5208 0.17864   5 0.07989 0.343 0.254, 0.736 -0.38
129S1/SvImJ m 0.6716 0.19906   5 0.08902 0.2964 0.519, 1.014 -0.51
A/J f 0.4119 0.10604   5 0.04742 0.2574 0.336, 0.5935 -0.6
A/J m 0.3251 0.09304   5 0.04161 0.2862 0.2045, 0.431 -1.28
C57BL/6J f 0.3322 0.0485   5 0.02169 0.146 0.287, 0.3875 -0.76
C57BL/6J m 0.6038 0.4413   5 0.19735 0.7309 0.125, 1.2605 -0.66
CAST/EiJ f 1.87 0.0   1   0.0 0.0 1.87, 1.87 2.33
CAST/EiJ m 0.99175 0.24643   2   0.17425 0.2485 0.8175, 1.166 0.2
DBA/2J f 0.69837 0.28035   4 0.14018 0.4014 0.439, 1.073 -0.03
DBA/2J m 1.3713 0.45806   5 0.20485 0.334 0.964, 2.1125 1.04
NOD/ShiLtJ f 0.84371 0.83831   7 0.31685 0.9936 0.099, 2.628 0.26
NOD/ShiLtJ m 1.1272 0.92192   5 0.4123 0.8179 0.4125, 2.688 0.5
PWK/PhJ f 0.6219 0.34397   5 0.15383 0.5531 0.3395, 1.185 -0.18
PWK/PhJ m 1.6167 0.95157   5 0.42555 0.5886 0.983, 3.292 1.59
WSB/EiJ f 0.398 0.15612   3 0.09014 0.3923 0.29, 0.577 -0.63
WSB/EiJ m 0.51225 0.20084   4 0.10042 0.3921 0.318, 0.7565 -0.87


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.5208 0.2286065637 0.9791285648 0.0624714352
129S1/SvImJ m 0.6716 0.2286065637 1.1299285648 0.2132714352
A/J f 0.4119 0.2286065637 0.8702285648 -0.0464285648
A/J m 0.3251 0.2286065637 0.7834285648 -0.1332285648
C57BL/6J f 0.3322 0.2286065637 0.7905285648 -0.1261285648
C57BL/6J m 0.6038 0.2286065637 1.0621285648 0.1454714352
DBA/2J f 0.698375 0.2555899083 1.2108019134 0.1859480866
DBA/2J m 1.3713 0.2286065637 1.8296285648 0.9129714352
NOD/ShiLtJ f 0.8437142857 0.19320781 1.2310726223 0.4563559491
NOD/ShiLtJ m 1.1272 0.2286065637 1.5855285648 0.6688714352
PWK/PhJ f 0.6219 0.2286065637 1.0802285648 0.1635714352
PWK/PhJ m 1.6167 0.2286065637 2.0750285648 1.1583714352
WSB/EiJ f 0.398 0.2951298047 0.9896996328 -0.1936996328
WSB/EiJ m 0.51225 0.2555899083 1.0246769134 -0.0001769134


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.5962 0.1616492514 0.9202872362 0.2721127638
A/J both 0.3685 0.1616492514 0.6925872362 0.0444127638
C57BL/6J both 0.468 0.1616492514 0.7920872362 0.1439127638
DBA/2J both 1.0348375 0.1714549228 1.3785839236 0.6910910764
NOD/ShiLtJ both 0.9854571429 0.1496581261 1.2855036202 0.6854106655
PWK/PhJ both 1.1193 0.1616492514 1.4433872362 0.7952127638
WSB/EiJ both 0.455125 0.195210017 0.8464975198 0.0637524802




  GWAS USING LINEAR MIXED MODELS