Project measure / variable:   Auwerx2   ogtt_gluc_t120_CD

ID, description, units MPD:114595   ogtt_gluc_t120_CD   glucose, glucose tolerance test (20% glucose oral gavage, overnight fast), after 120 min   [mg/dL]  CD  
Data set, strains Auwerx2   inbred w/CC8   8 strains     sex: both     age: 16wks
Procedure glucose tolerance
Ontology mappings

  STRAIN COMPARISON PLOT
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Auwerx2 - glucose, glucose tolerance test (20% glucose oral gavage, overnight fast), after 120 min CD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means102.9   mg/dL 133.5   mg/dL
Median of the strain means93.2   mg/dL 128.1   mg/dL
SD of the strain means± 27.782 ± 31.579
Coefficient of variation (CV)0.2699 0.2365
Min–max range of strain means65.0   –   145.8   mg/dL 84.0   –   172.4   mg/dL
Mean sample size per strain4.0   mice 4.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 6490.5807 6490.5807 14.7226 0.0003
strain 6 24865.8867 4144.3145 9.4005 < 0.0001
sex:strain 6 18819.4872 3136.5812 7.1147 < 0.0001
Residuals 52 22924.6667 440.859


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 93.2 10.895   5 4.8724 0.1169 80.0, 109.0 -0.35
129S1/SvImJ m 126.4 23.234   5 10.39 0.1838 108.0, 167.0 -0.23
A/J f 93.2 14.55   5 6.5069 0.1561 75.0, 106.0 -0.35
A/J m 159.2 33.848   5 15.137 0.2126 116.0, 193.0 0.81
C57BL/6J f 124.2 9.3648   5 4.1881 0.0754 115.0, 135.0 0.77
C57BL/6J m 172.4 13.939   5 6.2338 0.0809 156.0, 194.0 1.23
CAST/EiJ f 65.0 0.0   1   0.0 0.0 65.0, 65.0 -1.37
CAST/EiJ m 170.3 45.347   3 26.181 0.2662 118.0, 198.0 1.16
DBA/2J f 145.8 34.774   5 15.551 0.2385 95.0, 189.0 1.54
DBA/2J m 106.0 21.436   5 9.5864 0.2022 69.0, 124.0 -0.87
NOD/ShiLtJ f 84.33 24.028   3 13.872 0.2849 61.0, 109.0 -0.67
NOD/ShiLtJ m 84.0 21.817   5 9.757 0.2597 47.0, 105.0 -1.57
PWK/PhJ f 85.8 6.3797   5 2.8531 0.0744 77.0, 94.0 -0.62
PWK/PhJ m 120.0 14.595   5 6.5269 0.1216 96.0, 135.0 -0.43
WSB/EiJ f 132.0 19.975   3 11.533 0.1513 109.0, 145.0 1.05
WSB/EiJ m 129.8 23.382   5 10.457 0.1801 106.0, 165.0 -0.12


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 93.2 9.3899837525 112.0423808965 74.3576191035
129S1/SvImJ m 126.4 9.3899837525 145.2423808965 107.5576191035
A/J f 93.2 9.3899837525 112.0423808965 74.3576191035
A/J m 159.2 9.3899837525 178.0423808965 140.3576191035
C57BL/6J f 124.2 9.3899837525 143.0423808965 105.3576191035
C57BL/6J m 172.4 9.3899837525 191.2423808965 153.5576191035
DBA/2J f 145.8 9.3899837525 164.6423808965 126.9576191035
DBA/2J m 106.0 9.3899837525 124.8423808965 87.1576191035
NOD/ShiLtJ f 84.3333333333 12.1224168982 108.6587424717 60.007924195
NOD/ShiLtJ m 84.0 9.3899837525 102.8423808965 65.1576191035
PWK/PhJ f 85.8 9.3899837525 104.6423808965 66.9576191035
PWK/PhJ m 120.0 9.3899837525 138.8423808965 101.1576191035
WSB/EiJ f 132.0 12.1224168982 156.3254091383 107.6745908617
WSB/EiJ m 129.8 9.3899837525 148.6423808965 110.9576191035


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 109.8 6.6397211866 123.1235753056 96.4764246944
A/J both 126.2 6.6397211866 139.5235753056 112.8764246944
C57BL/6J both 148.3 6.6397211866 161.6235753056 134.9764246944
DBA/2J both 125.9 6.6397211866 139.2235753056 112.5764246944
NOD/ShiLtJ both 84.1666666667 7.6668896289 99.5514062452 68.7819270881
PWK/PhJ both 102.9 6.6397211866 116.2235753056 89.5764246944
WSB/EiJ both 130.9 7.6668896289 146.2847395785 115.5152604215




  GWAS USING LINEAR MIXED MODELS