Project measure / variable:   Auwerx2   ogtt_gluc_t90_CD

ID, description, units MPD:114593   ogtt_gluc_t90_CD   glucose, glucose tolerance test (20% glucose oral gavage, overnight fast), after 90 min   [mg/dL]  CD  
Data set, strains Auwerx2   inbred w/CC8   8 strains     sex: both     age: 16wks
Procedure glucose tolerance
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  STRAIN COMPARISON PLOT
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Auwerx2 - glucose, glucose tolerance test (20% glucose oral gavage, overnight fast), after 90 min CD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means126.1   mg/dL 169.4   mg/dL
Median of the strain means118.0   mg/dL 168.2   mg/dL
SD of the strain means± 37.438 ± 47.904
Coefficient of variation (CV)0.297 0.2828
Min–max range of strain means71.0   –   174.4   mg/dL 107.8   –   254.8   mg/dL
Mean sample size per strain4.0   mice 4.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 17026.4869 17026.4869 16.6607 0.0002
strain 6 69378.1564 11563.0261 11.3146 < 0.0001
sex:strain 6 33765.6962 5627.616 5.5067 0.0002
Residuals 52 53141.6 1021.9538


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 123.0 23.875   5 10.677 0.1941 101.0, 161.0 -0.08
129S1/SvImJ m 153.8 20.584   5 9.2054 0.1338 141.0, 190.0 -0.33
A/J f 108.0 33.971   5 15.192 0.3145 70.0, 148.0 -0.48
A/J m 182.6 48.118   5 21.519 0.2635 110.0, 224.0 0.28
C57BL/6J f 155.0 24.362   5 10.895 0.1572 115.0, 181.0 0.77
C57BL/6J m 254.8 34.974   5 15.641 0.1373 203.0, 288.0 1.78
CAST/EiJ f 71.0 0.0   1   0.0 0.0 71.0, 71.0 -1.47
CAST/EiJ m 199.7 46.479   3 26.835 0.2328 146.0, 227.0 0.63
DBA/2J f 174.4 40.389   5 18.063 0.2316 108.0, 214.0 1.29
DBA/2J m 129.2 10.803   5 4.8311 0.0836 118.0, 143.0 -0.84
NOD/ShiLtJ f 113.0 47.508   3 27.429 0.4204 66.0, 161.0 -0.35
NOD/ShiLtJ m 107.8 29.064   5 12.998 0.2696 61.0, 137.0 -1.29
PWK/PhJ f 93.2 22.928   5 10.254 0.246 58.0, 114.0 -0.88
PWK/PhJ m 132.4 15.453   5 6.9109 0.1167 107.0, 148.0 -0.77
WSB/EiJ f 171.0 10.149   3 5.8595 0.0594 162.0, 182.0 1.2
WSB/EiJ m 195.0 49.684   5 22.219 0.2548 126.0, 247.0 0.53


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 123.0 14.2965299717 151.6880861911 94.3119138089
129S1/SvImJ m 153.8 14.2965299717 182.4880861911 125.1119138089
A/J f 108.0 14.2965299717 136.6880861911 79.3119138089
A/J m 182.6 14.2965299717 211.2880861911 153.9119138089
C57BL/6J f 155.0 14.2965299717 183.6880861911 126.3119138089
C57BL/6J m 254.8 14.2965299717 283.4880861911 226.1119138089
DBA/2J f 174.4 14.2965299717 203.0880861911 145.7119138089
DBA/2J m 129.2 14.2965299717 157.8880861911 100.5119138089
NOD/ShiLtJ f 113.0 18.4567408296 150.0361600176 75.9638399824
NOD/ShiLtJ m 107.8 14.2965299717 136.4880861911 79.1119138089
PWK/PhJ f 93.2 14.2965299717 121.8880861911 64.5119138089
PWK/PhJ m 132.4 14.2965299717 161.0880861911 103.7119138089
WSB/EiJ f 171.0 18.4567408296 208.0361600176 133.9638399824
WSB/EiJ m 195.0 14.2965299717 223.6880861911 166.3119138089


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 138.4 10.1091732904 158.685540285 118.114459715
A/J both 145.3 10.1091732904 165.585540285 125.014459715
C57BL/6J both 204.9 10.1091732904 225.185540285 184.614459715
DBA/2J both 151.8 10.1091732904 172.085540285 131.514459715
NOD/ShiLtJ both 110.4 11.673067841 133.8237242884 86.9762757116
PWK/PhJ both 112.8 10.1091732904 133.085540285 92.514459715
WSB/EiJ both 183.0 11.673067841 206.4237242884 159.5762757116




  GWAS USING LINEAR MIXED MODELS