Project measure / variable:   Auwerx2   ogtt_gluc_t0_CD

ID, description, units MPD:114583   ogtt_gluc_t0_CD   glucose baseline, glucose tolerance test (pregavage, overnight fast)   [mg/dL]  CD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 16wks
Procedure glucose tolerance
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  STRAIN COMPARISON PLOT
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Auwerx2 - glucose baseline, glucose tolerance test (pregavage, overnight fast) CD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains9 strains
Mean of the strain means77.9   mg/dL 99.69   mg/dL
Median of the strain means75.7   mg/dL 92.6   mg/dL
SD of the strain means± 15.224 ± 36.497
Coefficient of variation (CV)0.1954 0.3661
Min–max range of strain means55.0   –   101.0   mg/dL 68.2   –   192.8   mg/dL
Mean sample size per strain4.0   mice 4.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 655.6333 655.6333 8.952 0.0042
strain 6 6869.8097 1144.9683 15.6334 < 0.0001
sex:strain 6 1345.6115 224.2686 3.0622 0.0122
Residuals 52 3808.4 73.2385


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 68.6 6.9138   5 3.0919 0.1008 60.0, 76.0 -0.61
129S1/SvImJ m 68.2 6.6483   5 2.9732 0.0975 64.0, 80.0 -0.86
A/J f 79.2 6.1806   5 2.7641 0.078 73.0, 87.0 0.09
A/J m 74.8 3.0332   5 1.3565 0.0406 70.0, 78.0 -0.68
C57BL/6J f 95.6 10.31   5 4.6109 0.1078 82.0, 109.0 1.16
C57BL/6J m 100.2 9.9348   5 4.443 0.0991 90.0, 114.0 0.01
CAST/EiJ f 55.0 0.0   1   0.0 0.0 55.0, 55.0 -1.5
CAST/EiJ m 95.0 13.0   3 7.5056 0.1368 82.0, 108.0 -0.13
DBA/2J f 83.6 14.1   5 6.3056 0.1687 61.0, 96.0 0.37
DBA/2J m 87.8 7.2938   5 3.2619 0.0831 76.0, 96.0 -0.33
NOD/ShiLtJ f 68.0 10.536   3 6.0828 0.1549 57.0, 78.0 -0.65
NOD/ShiLtJ m 87.0 4.5826   5 2.0494 0.0527 80.0, 92.0 -0.35
NZO/HlLtJ m 192.8 124.6   5 55.72 0.6462 114.0, 414.0 2.55
PWK/PhJ f 72.2 7.9812   5 3.5693 0.1105 67.0, 86.0 -0.37
PWK/PhJ m 92.6 8.0187   5 3.5861 0.0866 84.0, 103.0 -0.19
WSB/EiJ f 101.0 9.8489   3 5.6862 0.0975 93.0, 112.0 1.52
WSB/EiJ m 98.8 10.134   5 4.5321 0.1026 84.0, 110.0 -0.02


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 68.6 3.8272303703 76.2798995949 60.9201004051
129S1/SvImJ m 68.2 3.8272303703 75.8798995949 60.5201004051
A/J f 79.2 3.8272303703 86.8798995949 71.5201004051
A/J m 74.8 3.8272303703 82.4798995949 67.1201004051
C57BL/6J f 95.6 3.8272303703 103.2798995949 87.9201004051
C57BL/6J m 100.2 3.8272303703 107.8798995949 92.5201004051
DBA/2J f 83.6 3.8272303703 91.2798995949 75.9201004051
DBA/2J m 87.8 3.8272303703 95.4798995949 80.1201004051
NOD/ShiLtJ f 68.0 4.9409331621 77.9147077438 58.0852922562
NOD/ShiLtJ m 87.0 3.8272303703 94.6798995949 79.3201004051
PWK/PhJ f 72.2 3.8272303703 79.8798995949 64.5201004051
PWK/PhJ m 92.6 3.8272303703 100.2798995949 84.9201004051
WSB/EiJ f 101.0 4.9409331621 110.9147077438 91.0852922562
WSB/EiJ m 98.8 3.8272303703 106.4798995949 91.1201004051


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 68.4 2.706260548 73.8305090824 62.9694909176
A/J both 77.0 2.706260548 82.4305090824 71.5694909176
C57BL/6J both 97.9 2.706260548 103.3305090824 92.4694909176
DBA/2J both 85.7 2.706260548 91.1305090824 80.2694909176
NOD/ShiLtJ both 77.5 3.1249205118 83.7706117611 71.2293882389
PWK/PhJ both 82.4 2.706260548 87.8305090824 76.9694909176
WSB/EiJ both 99.9 3.1249205118 106.1706117611 93.6293882389




  GWAS USING LINEAR MIXED MODELS