Project measure / variable:   Auwerx2   ltm_pct_CD

ID, description, units MPD:114567   ltm_pct_CD   percentage lean tissue mass   [%]  CD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 14wks
Procedure MRI
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  STRAIN COMPARISON PLOT
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Auwerx2 - percentage lean tissue mass CD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means81.82   % 80.78   %
Median of the strain means83.97   % 83.26   %
SD of the strain means± 10.771 ± 9.0431
Coefficient of variation (CV)0.1316 0.112
Min–max range of strain means56.38   –   92.56   % 63.47   –   90.47   %
Mean sample size per strain4.0   mice 4.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1.1653 1.1653 0.081 0.777
strain 7 5655.5849 807.9407 56.1241 < 0.0001
sex:strain 7 515.5609 73.6516 5.1163 0.0001
Residuals 59 849.3408 14.3956


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 81.75 3.9972   5 1.7876 0.0489 74.87, 84.36 -0.01
129S1/SvImJ m 83.26 5.1405   5 2.2989 0.0617 75.02, 88.82 0.27
A/J f 75.64 2.5618   5 1.1457 0.0339 73.48, 80.06 -0.57
A/J m 78.06 1.7142   5 0.76662 0.022 76.12, 80.53 -0.3
C57BL/6J f 86.97 1.6354   5 0.73136 0.0188 84.97, 89.08 0.48
C57BL/6J m 88.68 2.3311   5 1.0425 0.0263 85.33, 91.06 0.87
CAST/EiJ f 92.56 0.0   1   0.0 0.0 92.56, 92.56 1.0
CAST/EiJ m 87.23 4.2545   3 2.4563 0.0488 84.3, 92.11 0.71
DBA/2J f 83.97 3.1182   5 1.3945 0.0371 80.96, 89.01 0.2
DBA/2J m 77.86 8.4632   5 3.7848 0.1087 65.85, 89.4 -0.32
NOD/ShiLtJ f 89.04 0.1222   3 0.07055 0.0014 88.91, 89.15 0.67
NOD/ShiLtJ m 90.47 1.8116   5 0.81015 0.02 88.09, 92.36 1.07
NZO/HlLtJ f 56.38 1.9826   4 0.9913 0.0352 53.62, 57.9 -2.36
NZO/HlLtJ m 63.47 3.5941   5 1.6073 0.0566 58.33, 68.22 -1.91
PWK/PhJ f 81.61 5.1111   5 2.2857 0.0626 73.01, 86.69 -0.02
PWK/PhJ m 70.98 3.6318   5 1.6242 0.0512 66.04, 76.13 -1.08
WSB/EiJ f 88.46 4.5416   3 2.6221 0.0513 84.69, 93.5 0.62
WSB/EiJ m 86.99 1.4812   5 0.66242 0.017 84.9, 88.7 0.69


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 81.754 1.6967973555 85.1492836659 78.3587163341
129S1/SvImJ m 83.258 1.6967973555 86.6532836659 79.8627163341
A/J f 75.64 1.6967973555 79.0352836659 72.2447163341
A/J m 78.062 1.6967973555 81.4572836659 74.6667163341
C57BL/6J f 86.966 1.6967973555 90.3612836659 83.5707163341
C57BL/6J m 88.68 1.6967973555 92.0752836659 85.2847163341
DBA/2J f 83.972 1.6967973555 87.3672836659 80.5767163341
DBA/2J m 77.858 1.6967973555 81.2532836659 74.4627163341
NOD/ShiLtJ f 89.0433333333 2.1905559665 93.4266256978 84.6600409688
NOD/ShiLtJ m 90.466 1.6967973555 93.8612836659 87.0707163341
NZO/HlLtJ f 56.38 1.8970771154 60.1760425399 52.5839574601
NZO/HlLtJ m 63.474 1.6967973555 66.8692836659 60.0787163341
PWK/PhJ f 81.61 1.6967973555 85.0052836659 78.2147163341
PWK/PhJ m 70.976 1.6967973555 74.3712836659 67.5807163341
WSB/EiJ f 88.4566666667 2.1905559665 92.8399590312 84.0733743022
WSB/EiJ m 86.994 1.6967973555 90.3892836659 83.5987163341


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 82.506 1.1998169164 84.9068281042 80.1051718958
A/J both 76.851 1.1998169164 79.2518281042 74.4501718958
C57BL/6J both 87.823 1.1998169164 90.2238281042 85.4221718958
DBA/2J both 80.915 1.1998169164 83.3158281042 78.5141718958
NOD/ShiLtJ both 89.7546666667 1.3854292393 92.5269041711 86.9824291622
NZO/HlLtJ both 59.927 1.2725980166 62.4734627494 57.3805372506
PWK/PhJ both 76.293 1.1998169164 78.6938281042 73.8921718958
WSB/EiJ both 87.7253333333 1.3854292393 90.4975708378 84.9530958289




  GWAS USING LINEAR MIXED MODELS