Project measure / variable:   Auwerx2   fat_pct_HFD

ID, description, units MPD:114566   fat_pct_HFD   percentage fat tissue mass   [%]  HFD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 14wks
Procedure MRI
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  STRAIN COMPARISON PLOT
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Auwerx2 - percentage fat tissue mass HFD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means26.276   % 30.724   %
Median of the strain means22.298   % 32.642   %
SD of the strain means± 13.16 ± 12.919
Coefficient of variation (CV)0.5008 0.4205
Min–max range of strain means12.829   –   54.88   % 12.084   –   53.56   %
Mean sample size per strain4.9   mice 3.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 462.7793 462.7793 15.0218 0.0003
strain 7 4471.1746 638.7392 20.7335 < 0.0001
sex:strain 7 584.8148 83.545 2.7119 0.0171
Residuals 56 1725.201 30.8072


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 21.695 2.8941   5 1.2943 0.1334 17.5, 24.455 -0.35
129S1/SvImJ m 36.548 4.343   2   3.071 0.1188 33.477, 39.619 0.45
A/J f 22.463 5.8271   4 2.9135 0.2594 16.982, 30.68 -0.29
A/J m 28.771 2.5749   5 1.1515 0.0895 26.524, 33.201 -0.15
C57BL/6J f 18.957 2.8737   3 1.6591 0.1516 16.709, 22.195 -0.56
C57BL/6J m 32.642 6.5926   4 3.2963 0.202 25.074, 40.405 0.15
CAST/EiJ f 12.829 1.3857   5 0.61971 0.108 11.397, 14.624 -1.02
CAST/EiJ m 14.967 2.9465   2   2.0835 0.1969 12.884, 17.051 -1.22
DBA/2J f 36.467 4.317   5 1.9306 0.1184 30.115, 42.005 0.77
DBA/2J m 34.673 1.0894   5 0.48718 0.0314 33.614, 36.033 0.31
NOD/ShiLtJ f 22.298 11.241   10 3.5548 0.5041 7.8635, 41.167 -0.3
NOD/ShiLtJ m 22.707 1.8498   5 0.82725 0.0815 21.062, 25.43 -0.62
NZO/HlLtJ f 54.88 1.435   5 0.64177 0.0261 53.32, 57.16 2.17
NZO/HlLtJ m 53.56 0.0   1   0.0 0.0 53.56, 53.56 1.77
PWK/PhJ f 32.441 3.3815   4 1.6908 0.1042 29.188, 37.092 0.47
PWK/PhJ m 40.56 2.7184   5 1.2157 0.067 38.194, 45.263 0.76
WSB/EiJ f 14.455 6.0814   3 3.5111 0.4207 8.6999, 20.817 -0.9
WSB/EiJ m 12.084 1.8085   5 0.80878 0.1497 10.186, 14.47 -1.44


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 21.6954 2.4822231977 26.6678905829 16.7229094171
129S1/SvImJ m 36.548 3.9247394828 44.4101979428 28.6858020572
A/J f 22.4635 2.7752099027 28.0229134804 16.9040865196
A/J m 28.7712 2.4822231977 33.7436905829 23.7987094171
C57BL/6J f 18.9573333333 3.2045363687 25.3767910722 12.5378755945
C57BL/6J m 32.6415 2.7752099027 38.2009134804 27.0820865196
CAST/EiJ f 12.8286 2.4822231977 17.8010905829 7.8561094171
CAST/EiJ m 14.9675 3.9247394828 22.8296979428 7.1053020572
DBA/2J f 36.4674 2.4822231977 41.4398905829 31.4949094171
DBA/2J m 34.6732 2.4822231977 39.6456905829 29.7007094171
NOD/ShiLtJ f 22.29754 1.7551968555 25.8136218105 18.7814581895
NOD/ShiLtJ m 22.707 2.4822231977 27.6794905829 17.7345094171
PWK/PhJ f 32.44075 2.7752099027 38.0001634804 26.8813365196
PWK/PhJ m 40.56 2.4822231977 45.5324905829 35.5875094171
WSB/EiJ f 14.4546333333 3.2045363687 20.8740910722 8.0351755945
WSB/EiJ m 12.0842 2.4822231977 17.0566905829 7.1117094171


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 29.1217 2.3219071908 33.77303903 24.47036097
A/J both 25.61735 1.8616673983 29.3467179371 21.8879820629
C57BL/6J both 25.7994166667 2.1196015747 30.0454888489 21.5533444844
CAST/EiJ both 13.89805 2.3219071908 18.54938903 9.24671097
DBA/2J both 35.5703 1.7551968555 39.0863818105 32.0542181895
NOD/ShiLtJ both 22.50227 1.5200450655 25.5472861697 19.4572538303
PWK/PhJ both 36.500375 1.8616673983 40.2297429371 32.7710070629
WSB/EiJ both 13.2694166667 2.026726754 17.3294382263 9.2093951071




  GWAS USING LINEAR MIXED MODELS