Project measure / variable:   Auwerx2   fat_CD

ID, description, units MPD:114561   fat_CD   fat tissue mass   [g]  CD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 14wks
Procedure MRI
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  STRAIN COMPARISON PLOT
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Auwerx2 - fat tissue mass CD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means5.0108   g 5.9346   g
Median of the strain means2.9578   g 3.8508   g
SD of the strain means± 6.7751 ± 5.3381
Coefficient of variation (CV)1.3521 0.8995
Min–max range of strain means0.899   –   22.646   g 1.6626   –   19.005   g
Mean sample size per strain4.0   mice 4.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 16.2704 16.2704 13.3114 0.0006
strain 7 2354.1889 336.3127 275.1503 < 0.0001
sex:strain 7 97.7353 13.9622 11.423 < 0.0001
Residuals 59 72.115 1.2223


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 3.476 1.1406   5 0.51008 0.3281 2.692, 5.461 -0.23
129S1/SvImJ m 3.8508 1.6306   5 0.72921 0.4234 2.542, 6.545 -0.39
A/J f 5.8058 0.46814   5 0.20936 0.0806 5.248, 6.402 0.12
A/J m 5.9048 0.52865   5 0.23642 0.0895 5.255, 6.558 -0.01
C57BL/6J f 2.0414 0.50435   5 0.22555 0.2471 1.375, 2.709 -0.44
C57BL/6J m 3.438 0.78149   5 0.34949 0.2273 2.696, 4.649 -0.47
CAST/EiJ f 0.899 0.0   1   0.0 0.0 0.899, 0.899 -0.61
CAST/EiJ m 2.216 0.66377   3 0.38323 0.2995 1.45, 2.622 -0.7
DBA/2J f 3.7488 0.81734   5 0.36552 0.218 2.563, 4.659 -0.19
DBA/2J m 7.2852 1.4509   5 0.64884 0.1992 6.005, 9.647 0.25
NOD/ShiLtJ f 2.298 0.17903   3 0.10337 0.0779 2.134, 2.489 -0.4
NOD/ShiLtJ m 2.6802 0.60926   5 0.27247 0.2273 2.05, 3.567 -0.61
NZO/HlLtJ f 22.646 2.1591   4 1.0795 0.0953 20.667, 24.79 2.6
NZO/HlLtJ m 19.005 1.7205   5 0.76944 0.0905 17.192, 21.145 2.45
PWK/PhJ f 2.9578 1.2629   5 0.56479 0.427 1.561, 5.024 -0.3
PWK/PhJ m 7.3684 1.1392   5 0.50948 0.1546 6.031, 9.179 0.27
WSB/EiJ f 1.224 0.44487   3 0.25684 0.3635 0.72, 1.562 -0.56
WSB/EiJ m 1.6626 0.3114   5 0.13926 0.1873 1.362, 2.151 -0.8


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 3.476 0.4944264102 4.4653449616 2.4866550384
129S1/SvImJ m 3.8508 0.4944264102 4.8401449616 2.8614550384
A/J f 5.8058 0.4944264102 6.7951449616 4.8164550384
A/J m 5.9048 0.4944264102 6.8941449616 4.9154550384
C57BL/6J f 2.0414 0.4944264102 3.0307449616 1.0520550384
C57BL/6J m 3.438 0.4944264102 4.4273449616 2.4486550384
DBA/2J f 3.7488 0.4944264102 4.7381449616 2.7594550384
DBA/2J m 7.2852 0.4944264102 8.2745449616 6.2958550384
NOD/ShiLtJ f 2.298 0.6383017509 3.5752388533 1.0207611467
NOD/ShiLtJ m 2.6802 0.4944264102 3.6695449616 1.6908550384
NZO/HlLtJ f 22.64625 0.5527855315 23.7523712936 21.5401287064
NZO/HlLtJ m 19.0046 0.4944264102 19.9939449616 18.0152550384
PWK/PhJ f 2.9578 0.4944264102 3.9471449616 1.9684550384
PWK/PhJ m 7.3684 0.4944264102 8.3577449616 6.3790550384
WSB/EiJ f 1.224 0.6383017509 2.5012388533 -0.0532388533
WSB/EiJ m 1.6626 0.4944264102 2.6519449616 0.6732550384


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 3.6634 0.3496122674 4.3629725313 2.9638274687
A/J both 5.8553 0.3496122674 6.5548725313 5.1557274687
C57BL/6J both 2.7397 0.3496122674 3.4392725313 2.0401274687
DBA/2J both 5.517 0.3496122674 6.2165725313 4.8174274687
NOD/ShiLtJ both 2.4891 0.4036974734 3.2968967785 1.6813032215
NZO/HlLtJ both 20.825425 0.3708198076 21.5674337212 20.0834162788
PWK/PhJ both 5.1631 0.3496122674 5.8626725313 4.4635274687
WSB/EiJ both 1.4433 0.4036974734 2.2510967785 0.6355032215




  GWAS USING LINEAR MIXED MODELS